Karmanos Executive and Leadership Team

September, 2026

Leadership Overview

Karmanos has 10 executives leading key functions including strategy, clinical operations, financial oversight, and technological infrastructure.

Dedicated to advancing oncology through rigorous scientific investigation, Karmanos maintains a commitment to comprehensive cancer care and the expansion of life-saving clinical trials across the North American medical landscape.

Leadership Roles at Karmanos

  • President & Chief Executive Officer - Bepler Gerold
  • President & Chief Executive Officer - Boris Pasche MD PhD
  • Vice President & Chief Financial Officer - Regina Doxtader
  • Chief Operating Officer - William Bennett
  • Clinical Research Coordinator III & Chief Technology Officer, Monitor - Supraja Chalasani
  • Office Manager, Chief Technology Officer - Lydia Jakovski
  • Chief Technology Officer, Bmt & Tumor Registrar - Yolanda Clay
  • Chief Technology Officer, Operations & Manager - Leah Dunham
  • Office Manager Chief Technology Officer - Donna Dexter
  • BMT-CTO, Oncologist Data Specialist, Chief Technology Officer Operations - Mayan Ajamoughli
  • Bepler Gerold - President & Chief Executive Officer

    Bepler Gerold, the President & Chief Executive Officer at Karmanos, directs the overarching strategic vision for cancer care and research initiatives. Overseeing the integration of scientific investigation programs with patient treatment protocols, the President & Chief Executive Officer ensures alignment with the mission of providing comprehensive oncology services. This leadership role involves managing high-level partnerships with academic institutions and clinical research networks to accelerate the development of novel therapies. By prioritizing patient outcomes and institutional growth, Bepler Gerold directly impacts the efficacy of cancer treatment delivery. The President & Chief Executive Officer maintains rigorous standards for clinical excellence, ensuring that the organization remains at the forefront of medical innovation while expanding the reach of specialized care across the region.
    Bepler Gerold

    Boris Pasche MD PhD - President & Chief Executive Officer

    Boris Pasche MD PhD, the President & Chief Executive Officer at Karmanos, architects the long-term operational framework for clinical trials and research-driven patient care. Focusing on the expansion of oncology-specific scientific investigation, the President & Chief Executive Officer drives the implementation of advanced diagnostic tools and therapeutic methodologies. This role requires constant collaboration with the Board to secure funding and resources for large-scale research projects. By optimizing the clinical trial pipeline, Boris Pasche MD PhD enhances the ability of the institution to offer cutting-edge treatments to a diverse patient population. The President & Chief Executive Officer manages the strategic deployment of medical assets, ensuring that research findings translate into improved clinical outcomes. Pasche maintains a focus on sustainable growth, positioning the organization as a leader in the competitive landscape of cancer research.
    Boris Pasche MD PhD

    Regina Doxtader - Vice President & Chief Financial Officer

    Regina Doxtader, the Vice President & Chief Financial Officer at Karmanos, directs the financial strategy and fiscal health of the organization. Overseeing the budgeting process, revenue cycle management, and capital investments, the Vice President & Chief Financial Officer ensures that resources support the mission of providing comprehensive cancer care. This role involves analyzing financial performance to identify opportunities for growth and operational efficiency. By managing the financial risks associated with clinical trials and research programs, Regina Doxtader secures the long-term stability of the institution. The Vice President & Chief Financial Officer collaborates with the executive team to align financial planning with strategic objectives. Doxtader drives the implementation of cost-saving measures, ensuring that the organization remains financially robust while continuing to invest in the latest medical technologies and scientific investigation programs.
    Regina Doxtader

    William Bennett - Chief Operating Officer

    William Bennett, the Chief Operating Officer at Karmanos, manages the daily administrative and clinical workflows that support cancer care delivery. Overseeing the efficiency of hospital operations, the Chief Operating Officer ensures that resources align with the needs of patients and medical staff. This leadership role involves streamlining internal processes to improve service delivery and patient throughput. By coordinating across departments, William Bennett facilitates a cohesive environment where clinical trials and standard treatments function in tandem. The Chief Operating Officer monitors performance metrics to identify areas for operational improvement, ensuring that the facility maintains high standards of care. Bennett drives the execution of organizational policies, supporting the broader mission of providing accessible and effective cancer treatment while maintaining fiscal responsibility and operational excellence throughout the entire clinical network.
    William Bennett

    Supraja Chalasani - Clinical Research Coordinator III & Chief Technology Officer, Monitor

    Supraja Chalasani, the Clinical Research Coordinator III & Chief Technology Officer, Monitor at Karmanos, architects the digital infrastructure required for monitoring complex clinical trials. Overseeing the integrity of research data, the Chief Technology Officer, Monitor ensures compliance with regulatory standards and internal quality protocols. This role involves integrating advanced software solutions to track patient progress and treatment efficacy. By managing the technological aspects of research, Supraja Chalasani supports the scientific investigation programs that define the organization. The Chief Technology Officer, Monitor collaborates with clinical teams to ensure that data collection remains accurate and accessible for ongoing studies. Chalasani drives the adoption of new monitoring technologies, enhancing the precision of research outcomes and supporting the overall mission of advancing cancer care through data-driven insights and rigorous scientific methodology.

    Lydia Jakovski - Office Manager, Chief Technology Officer

    Lydia Jakovski, the Office Manager, Chief Technology Officer at Karmanos, directs the administrative and technological systems that support daily clinical operations. Overseeing the maintenance of office infrastructure and digital platforms, the Chief Technology Officer ensures that staff members possess the tools necessary for efficient patient care. This role involves managing the procurement of technology and the optimization of internal communication systems. By streamlining administrative workflows, Lydia Jakovski enhances the productivity of the oncology teams. The Chief Technology Officer coordinates with department heads to align technological capabilities with the evolving needs of the cancer care environment. Jakovski drives the implementation of secure data management practices, ensuring that patient information remains protected while facilitating seamless access for authorized medical personnel. This leadership role supports the operational stability required for high-quality cancer treatment.

    Yolanda Clay - Chief Technology Officer, Bmt & Tumor Registrar

    Yolanda Clay, the Chief Technology Officer, Bmt & Tumor Registrar at Karmanos, architects the specialized data systems used for bone marrow transplant tracking and tumor registry management. Overseeing the accuracy of oncology records, the Chief Technology Officer, Bmt & Tumor Registrar ensures that critical patient data remains available for research and clinical decision-making. This role involves managing the digital databases that track long-term patient outcomes and treatment success rates. By maintaining these registries, Yolanda Clay supports the scientific investigation programs that characterize the institution. The Chief Technology Officer, Bmt & Tumor Registrar collaborates with oncologists to ensure that data reflects the latest clinical findings. Clay drives the integration of new registry software, enhancing the ability of the organization to analyze trends in cancer care and improve patient survival rates through precise data management.

    Leah Dunham - Chief Technology Officer, Operations & Manager

    Leah Dunham, the Chief Technology Officer, Operations & Manager at Karmanos, directs the technological systems that underpin clinical operations and facility management. Overseeing the deployment of software solutions, the Chief Technology Officer, Operations & Manager ensures that operational workflows remain efficient and scalable. This role involves managing the intersection of technology and patient care delivery, ensuring that systems support the needs of the oncology staff. By optimizing operational processes, Leah Dunham facilitates a smoother experience for both patients and providers. The Chief Technology Officer, Operations & Manager collaborates with leadership to align technological investments with the strategic goals of the organization. Dunham drives the adoption of new operational tools, enhancing the overall capacity of the facility to provide comprehensive cancer care while maintaining high standards of service and efficiency.
    Leah Dunham

    Donna Dexter - Office Manager Chief Technology Officer

    Donna Dexter, the Office Manager Chief Technology Officer at Karmanos, manages the administrative and technological functions that support the oncology department. Overseeing the daily operations of the office, the Chief Technology Officer ensures that digital systems remain functional and secure. This role involves coordinating with clinical staff to address technological needs and improve administrative efficiency. By managing the flow of information and resources, Donna Dexter supports the delivery of high-quality cancer care. The Chief Technology Officer implements strategies to streamline office processes, reducing the burden on medical personnel. Dexter drives the integration of new office technologies, ensuring that the facility remains equipped to handle the demands of modern cancer treatment. This leadership role is essential for maintaining the operational continuity required to support the mission of the organization.

    Mayan Ajamoughli - BMT-CTO, Oncologist Data Specialist, Chief Technology Officer Operations

    Mayan Ajamoughli, the BMT-CTO, Oncologist Data Specialist, Chief Technology Officer Operations at Karmanos, architects the data systems used for bone marrow transplant operations and oncology research. Overseeing the analysis of clinical data, the Chief Technology Officer Operations ensures that oncologists have access to accurate information for patient treatment. This role involves managing the technological infrastructure that supports complex transplant procedures and data-heavy research studies. By optimizing data management, Mayan Ajamoughli enhances the ability of the organization to conduct high-impact scientific investigations. The Chief Technology Officer Operations collaborates with clinical teams to ensure that data systems meet the specific needs of the oncology department. Ajamoughli drives the implementation of advanced data analytics, supporting the mission of improving cancer care through precise, evidence-based decision-making and technological innovation.
    Mayan Ajamoughli

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    Frequently Asked Questions Regarding Karmanos Top Executives and Leadership Team

    Who leads Karmanos?
    Karmanos is led by Bepler Gerold (President & Chief Executive Officer), along with executives such as Boris Pasche MD PhD (President & Chief Executive Officer) and Regina Doxtader (Vice President & Chief Financial Officer).
    Who is part of Karmanos’s executive team?
    The executive team of Karmanos includes leaders such as Bepler Gerold (President & Chief Executive Officer), Boris Pasche MD PhD (President & Chief Executive Officer), Regina Doxtader (Vice President & Chief Financial Officer) and other senior executives.
    How many executives does Karmanos have?
    Karmanos has 10 executives leading key business areas.
    What roles are included in Karmanos’s leadership team?
    The leadership team of Karmanos includes roles such as President & Chief Executive Officer, President & Chief Executive Officer, Vice President & Chief Financial Officer, Chief Operating Officer, Clinical Research Coordinator III & Chief Technology Officer, Monitor.