Harbor City Unlimited Executive and Leadership Team

September, 2026

Leadership Overview

Harbor City Unlimited has 6 executives leading key functions including strategy, technology, operations, finance, marketing, and external affairs.

Committed to advancing academic medicine, Harbor City Unlimited delivers specialized trauma, cancer, and transplant care while fostering innovation through its partnership with the University of Maryland School of Medicine.

Leadership Roles at Harbor City Unlimited

  • Chief Executive Officer - Whye DePriest
  • MS Senior VP & Chief Financial Officer - S Michelle Lee
  • Senior Vice President and Chief Operating Officer - Trent Smith
  • Chief Technology Officer - Charlene Smith
  • Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center - Stephen Smith
  • Chief of Staff & Senior VP, External Affairs - Kristin Bryce
  • Whye DePriest - Chief Executive Officer

    Whye DePriest, the Chief Executive Officer at Harbor City Unlimited, directs the overarching strategic vision for the academic medical center. DePriest manages the integration of clinical excellence with research initiatives across the downtown and midtown campuses. By aligning the medical staff with the University of Maryland School of Medicine, the Chief Executive Officer ensures high-quality patient outcomes in complex specialties like neurosciences and orthopedics. Whye DePriest oversees the expansion of trauma services at the R Adams Cowley Shock Trauma Center to maintain regional leadership in critical care. This executive role involves constant collaboration with the Board to secure long-term financial health and operational sustainability. Through rigorous oversight of the 789-bed downtown facility, the Chief Executive Officer drives the mission of providing advanced healthcare solutions. Ultimately, DePriest secures the institution's reputation as a premier academic medical center within the competitive healthcare landscape.

    S Michelle Lee - MS Senior VP & Chief Financial Officer

    S Michelle Lee, the MS Senior VP & Chief Financial Officer at Harbor City Unlimited, directs the fiscal strategy and capital allocation for the entire medical center. Lee manages the budgeting process to support the high costs associated with trauma services and specialized transplant medicine. By analyzing financial performance, the MS Senior VP & Chief Financial Officer ensures the institution maintains the resources needed for academic research and clinical expansion. S Michelle Lee oversees the financial planning for the Marlene and Stewart Greenebaum Comprehensive Cancer Center to sustain long-term growth. This leadership role involves constant interaction with the Board to report on revenue cycles and cost-containment initiatives. Through prudent fiscal management, the MS Senior VP & Chief Financial Officer supports the overall sustainability of the hospital's mission. Ultimately, Lee secures the financial health necessary to provide world-class healthcare services to the community.

    Trent Smith - Senior Vice President and Chief Operating Officer

    Trent Smith, the Senior Vice President and Chief Operating Officer at Harbor City Unlimited, manages the daily logistical functions of the 789-bed downtown and 177-bed midtown campuses. Smith directs the allocation of resources to ensure optimal patient flow and facility readiness for trauma and transplant services. By streamlining operational processes, the Senior Vice President and Chief Operating Officer maintains high standards of care delivery across all specialized units. Trent Smith oversees the coordination between administrative staff and clinical departments to maximize hospital capacity and service efficiency. This leadership role involves constant monitoring of operational metrics to identify areas for improvement in patient throughput. Through effective management of hospital infrastructure, the Senior Vice President and Chief Operating Officer supports the broader mission of providing comprehensive medical care. Ultimately, Smith secures the operational stability required for the medical center to function effectively in a high-demand environment.

    Charlene Smith - Chief Technology Officer

    Charlene Smith, the Chief Technology Officer at Harbor City Unlimited, architects the digital infrastructure supporting advanced clinical operations. Smith manages the implementation of electronic health records and data analytics platforms to improve patient care efficiency across all medical departments. By modernizing the technological framework, the Chief Technology Officer enables seamless communication between faculty physicians and residents. Charlene Smith drives the adoption of cutting-edge diagnostic tools within the Marlene and Stewart Greenebaum Comprehensive Cancer Center to enhance treatment precision. This leadership role requires constant coordination with the C-suite to ensure cybersecurity and data integrity across the entire hospital network. By optimizing digital workflows, the Chief Technology Officer directly impacts the speed and accuracy of medical interventions. Ultimately, Smith secures the technological foundation necessary for the institution to remain at the forefront of medical innovation and patient-centered service delivery.

    Stephen Smith - Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center

    Stephen Smith, the Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center at Harbor City Unlimited, directs the brand strategy and community outreach efforts. Smith manages the communication channels that connect the medical center with patients seeking specialized care in orthopedics and neurosciences. By promoting the institution's academic partnership, the Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center enhances the visibility of the hospital's unique clinical offerings. Stephen Smith oversees the development of marketing campaigns that highlight the expertise of faculty physicians and the success of the trauma center. This leadership role involves constant engagement with regional stakeholders to build trust and expand the patient base. Through strategic messaging, the Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center drives awareness of the center's comprehensive health services. Ultimately, Smith secures the brand reputation required for continued market growth.

    Kristin Bryce - Chief of Staff & Senior VP, External Affairs

    Kristin Bryce, the Chief of Staff & Senior VP, External Affairs at Harbor City Unlimited, directs the institutional relationships and government affairs strategy. Bryce manages the interactions between the medical center and external partners, including the University of Maryland School of Medicine. By fostering these critical alliances, the Chief of Staff & Senior VP, External Affairs ensures alignment with broader academic and public health goals. Kristin Bryce oversees the advocacy efforts that support the funding and regulatory needs of the trauma and transplant programs. This leadership role involves constant coordination with the executive team to manage high-level institutional priorities and public policy initiatives. Through effective external engagement, the Chief of Staff & Senior VP, External Affairs strengthens the hospital's position within the regional healthcare ecosystem. Ultimately, Bryce secures the collaborative environment necessary for the institution to achieve its long-term strategic objectives.

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    Frequently Asked Questions Regarding Harbor City Unlimited Top Executives and Leadership Team

    Who leads Harbor City Unlimited?
    Harbor City Unlimited is led by Whye DePriest (Chief Executive Officer), along with executives such as S Michelle Lee (MS Senior VP & Chief Financial Officer) and Trent Smith (Senior Vice President and Chief Operating Officer).
    Who is part of Harbor City Unlimited’s executive team?
    The executive team of Harbor City Unlimited includes leaders such as Whye DePriest (Chief Executive Officer), S Michelle Lee (MS Senior VP & Chief Financial Officer), Trent Smith (Senior Vice President and Chief Operating Officer) and other senior executives.
    How many executives does Harbor City Unlimited have?
    Harbor City Unlimited has 6 executives leading key business areas.
    What roles are included in Harbor City Unlimited’s leadership team?
    The leadership team of Harbor City Unlimited includes roles such as Chief Executive Officer, MS Senior VP & Chief Financial Officer, Senior Vice President and Chief Operating Officer, Chief Technology Officer, Senior Vice President and Chief Marketing Officer, Charles Regional Medical Center.