Tempus Executive and Leadership Team

October, 2026

Leadership Overview

Tempus has 6 executives leading key functions including information technology, software engineering, marketing, operational data, business development, and diagnostic innovation.

Committed to advancing precision medicine through data-driven insights, Tempus transforms healthcare by integrating clinical and molecular datasets to enable highly personalized therapeutic interventions for patients worldwide.

Leadership Roles at Tempus

  • Chief Operating Officer, Data & Apps - Max Banaszak
  • Chief Information Officer - Natasha Esprey
  • Chief Technology Officer - Shane Colley
  • Chief Marketing Officer - Patricia Spiller
  • Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data - Janelle Okrzesik
  • Chief Technology Officer, Diagnostics - Donavan Cheng
  • Max Banaszak - Chief Operating Officer, Data & Apps

    Max Banaszak, the Chief Operating Officer, Data & Apps at Tempus, manages the operational efficiency of the company's data ingestion and application deployment pipelines. Overseeing the normalization of vast amounts of unstructured text from electronic health records, the Chief Operating Officer, Data & Apps ensures that the data engine functions with maximum precision. Banaszak coordinates the internal processes that unify disparate patient history fragments, allowing for the creation of comprehensive, multimodal profiles. By streamlining the application development lifecycle, the Chief Operating Officer, Data & Apps supports the rapid deployment of predictive modeling tools to clinical practitioners. Max Banaszak maintains the operational scale required to process deep molecular sequencing data gathered from internal laboratory facilities. This leadership role involves optimizing the workflow between data science teams and software developers to ensure consistent product performance. Through meticulous management of data operations, Banaszak enables the organization to deliver actionable insights that help doctors uncover hidden diagnostic risks and forecast therapeutic reactions.

    Natasha Esprey - Chief Information Officer

    Natasha Esprey, the Chief Information Officer at Tempus, directs the enterprise-wide data architecture and information security frameworks. Overseeing the integrity of massive clinical and molecular datasets, the Chief Information Officer ensures that internal systems remain compliant with global healthcare regulations while supporting high-speed computational analysis. Esprey manages the digital infrastructure that allows medical practitioners to access normalized patient records seamlessly. By optimizing the flow of unstructured text from electronic health records into the proprietary data engine, the Chief Information Officer facilitates the generation of comprehensive, multimodal patient profiles. This leadership role involves constant collaboration with engineering teams to refine the neural networks that identify therapeutic correlations. Natasha Esprey maintains the technological backbone necessary for precision medicine, ensuring that the organization scales its diagnostic capabilities across diverse medical specialties. Through rigorous oversight of information systems, Esprey secures the foundation for advanced predictive modeling and long-term clinical research success.
    Natasha Esprey

    Shane Colley - Chief Technology Officer

    Shane Colley, the Chief Technology Officer at Tempus, architects the core artificial intelligence and machine learning platforms that define the company's market position. Managing the development of advanced algorithms, the Chief Technology Officer drives the evolution of the proprietary data engine used to analyze complex genomic and clinical information. Colley oversees the technical roadmap for software products that assist oncologists and cardiologists in selecting targeted therapeutics. By integrating deep molecular sequencing data with clinical history, the Chief Technology Officer enables the identification of invisible genetic patterns that influence patient outcomes. Shane Colley coordinates with cross-functional teams to ensure that predictive data modeling remains at the cutting edge of the healthcare industry. This leadership role focuses on expanding the computational capacity of the platform to handle increasing volumes of unstructured medical data. Through continuous innovation in software engineering, Colley supports the transition toward a precision-based therapeutic model, ultimately enhancing the diagnostic accuracy of the entire organization.
    Shane Colley

    Patricia Spiller - Chief Marketing Officer

    Patricia Spiller, the Chief Marketing Officer at Tempus, executes the global brand strategy and market positioning for the company's precision medicine platform. Overseeing the communication of complex diagnostic value propositions, the Chief Marketing Officer ensures that medical institutions and clinical practitioners understand the benefits of integrating algorithmic analysis into standard care. Spiller manages the outreach initiatives that highlight the organization's role in transforming oncology and neuropsychiatry through data-driven insights. By aligning marketing efforts with the company's mission to move away from one-size-fits-all treatments, the Chief Marketing Officer drives adoption of the proprietary software platform across diverse healthcare markets. Patricia Spiller collaborates with product teams to translate technical breakthroughs into compelling narratives for the medical community. This leadership role involves analyzing market trends to identify new opportunities for growth in the precision-based therapeutic sector. Through strategic brand management, Spiller strengthens the company's reputation as a leader in clinical data science and advanced genomic diagnostics.
    Patricia Spiller

    Janelle Okrzesik - Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data

    Janelle Okrzesik, the Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data at Tempus, drives revenue growth through strategic partnerships in the oncology and real-world data sectors. Overseeing the expansion of the Tempus Compass program, the Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data secures collaborations with pharmaceutical companies and research institutions. Okrzesik manages the commercialization of AI-driven insights to accelerate clinical trials and improve patient recruitment strategies. By identifying new market opportunities for real-world data applications, the Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data ensures the financial sustainability of the company's precision medicine initiatives. Janelle Okrzesik coordinates with the executive team to align revenue targets with the organization's broader mission of transforming healthcare. This leadership role involves navigating complex regulatory environments to expand the reach of diagnostic services. Through proactive business development, Okrzesik secures the resources necessary to advance the company's technological capabilities and clinical impact.

    Donavan Cheng - Chief Technology Officer, Diagnostics

    Donavan Cheng, the Chief Technology Officer, Diagnostics at Tempus, leads the technological advancement of the company's state-of-the-art laboratory facilities and genomic sequencing capabilities. Overseeing the integration of molecular data into the broader diagnostic platform, the Chief Technology Officer, Diagnostics ensures that laboratory processes meet the highest standards of accuracy and speed. Cheng manages the technical teams responsible for the sequencing and analysis of patient samples, which form the basis of the company's multimodal profiles. By refining the diagnostic pipeline, the Chief Technology Officer, Diagnostics enables the identification of specific genetic patterns that guide targeted therapeutics. Donavan Cheng collaborates with the broader technology leadership to ensure that laboratory data flows seamlessly into the predictive modeling engine. This leadership role focuses on scaling diagnostic operations to support the company's mission of precision medicine. Through continuous improvement of sequencing technologies, Cheng provides the essential molecular insights that allow medical practitioners to make informed, data-backed decisions for complex pathologies.
    Donavan Cheng

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    Frequently Asked Questions Regarding Tempus Top Executives and Leadership Team

    Who leads Tempus?
    Tempus is led by Max Banaszak (Chief Operating Officer, Data & Apps), along with executives such as Natasha Esprey (Chief Information Officer) and Shane Colley (Chief Technology Officer).
    Who is part of Tempus’s executive team?
    The executive team of Tempus includes leaders such as Max Banaszak (Chief Operating Officer, Data & Apps), Natasha Esprey (Chief Information Officer), Shane Colley (Chief Technology Officer) and other senior executives.
    How many executives does Tempus have?
    Tempus has 6 executives leading key business areas.
    What roles are included in Tempus’s leadership team?
    The leadership team of Tempus includes roles such as Chief Operating Officer, Data & Apps, Chief Information Officer, Chief Technology Officer, Chief Marketing Officer, Business Development Director, Tempus Compass & Chief Revenue Officer, Oncology Trials, Ai & Real-World Data.