Crinetics Pharmaceuticals Executive and Leadership Team

October, 2026

Leadership Overview

Crinetics Pharmaceuticals has 6 executives leading key functions including financial strategy, operational alliance management, human capital development, administrative support, medical affairs, and legal governance.

Focused on advancing endocrine health, Crinetics Pharmaceuticals delivers transformative therapies by targeting G protein-coupled receptors to address significant unmet patient needs through rigorous in-house drug discovery.

Leadership Roles at Crinetics Pharmaceuticals

  • Chief Financial Officer - Tobin Schilke
  • Chief of Staff To the Chief Operating Officer and Head of Alliance Management - Niccole Le
  • Chief Human Resources Officer - Adriana Cabre
  • Executive Assistant To the Chief Human Resources Officer - Natalie Berwald
  • Affairs Operations Senior Director, Medical & Chief of Staff - Rafael Marino
  • Chief Legal Officer - Garlan Adams
  • Tobin Schilke - Chief Financial Officer

    Tobin Schilke, the Chief Financial Officer at Crinetics Pharmaceuticals, directs all fiscal planning and capital allocation strategies. Overseeing the financial health of the organization, the Chief Financial Officer ensures alignment between R&D investment and long-term market value. This leadership role involves managing investor relations and securing the necessary funding to support the development of novel molecules targeting endocrine diseases. By optimizing the capital structure, Tobin Schilke directly impacts the ability of the company to scale its pipeline. Schilke maintains rigorous oversight of budgetary controls, ensuring that resources flow efficiently toward high-impact drug discovery programs. Through precise financial forecasting and risk management, the Chief Financial Officer supports the broader mission of delivering effective disease control to patients globally. Ultimately, Schilke secures the financial stability required for sustained innovation within the competitive pharmaceutical landscape.
    Tobin Schilke

    Niccole Le - Chief of Staff To the Chief Operating Officer and Head of Alliance Management

    Niccole Le, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management at Crinetics Pharmaceuticals, coordinates cross-functional operations and manages external partnerships. Overseeing the integration of strategic alliances, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management ensures that collaborative efforts with healthcare practitioners remain productive and focused on solving real clinical problems. This leadership role involves streamlining internal processes to enhance operational efficiency across the R&D pipeline. By facilitating communication between the executive team and external stakeholders, Niccole Le directly impacts the speed and efficacy of drug development initiatives. Le maintains a clear view of operational bottlenecks, implementing solutions that allow the company to focus on endocrine system breakthroughs. Through proactive management of complex partnerships, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management drives the organizational agility necessary for market success.

    Adriana Cabre - Chief Human Resources Officer

    Adriana Cabre, the Chief Human Resources Officer at Crinetics Pharmaceuticals, architects the talent acquisition and organizational culture strategies. Overseeing the recruitment of top-tier drug discovery scientists, the Chief Human Resources Officer ensures that the company maintains the specialized expertise required to develop transformative molecules. This leadership role involves fostering an environment of innovation that attracts professionals dedicated to endocrine disease research. By aligning human capital initiatives with the broader corporate mission, Adriana Cabre directly impacts the retention of high-performing teams. Cabre manages performance development programs that empower staff to push the boundaries of GPCR research. Through the implementation of robust talent management frameworks, the Chief Human Resources Officer supports the growth of the R&D team. Ultimately, Cabre builds the internal foundation necessary for the company to deliver innovative therapies to patients seeking effective disease control.
    Adriana Cabre

    Natalie Berwald - Executive Assistant To the Chief Human Resources Officer

    Natalie Berwald, the Executive Assistant To the Chief Human Resources Officer at Crinetics Pharmaceuticals, manages the administrative infrastructure supporting human capital operations. Overseeing the scheduling and logistical coordination for the HR department, the Executive Assistant To the Chief Human Resources Officer ensures that leadership can focus on strategic talent initiatives. This leadership role involves organizing critical documentation and facilitating communication between the HR team and other departments. By maintaining efficient workflows, Natalie Berwald directly impacts the productivity of the human resources function. Berwald handles complex administrative tasks that allow the Chief Human Resources Officer to dedicate time to high-level organizational planning and culture building. Through meticulous attention to detail and process management, the Executive Assistant To the Chief Human Resources Officer supports the smooth operation of the company. Ultimately, Berwald provides the essential support required for the HR team to attract and retain the talent necessary for drug discovery.

    Rafael Marino - Affairs Operations Senior Director, Medical & Chief of Staff

    Rafael Marino, the Affairs Operations Senior Director, Medical & Chief of Staff at Crinetics Pharmaceuticals, directs the operational execution of medical affairs and internal strategic alignment. Overseeing the integration of clinical insights into the R&D process, the Affairs Operations Senior Director, Medical & Chief of Staff ensures that the company remains responsive to the needs of healthcare practitioners. This leadership role involves managing the flow of medical information and coordinating internal efforts to support the development of therapies for endocrine diseases. By bridging the gap between clinical research and operational execution, Rafael Marino directly impacts the success of the pipeline. Marino maintains oversight of medical operations, ensuring that all activities align with the goal of providing effective disease control. Through strategic coordination and operational rigor, the Affairs Operations Senior Director, Medical & Chief of Staff supports the company's mission to solve real problems for patients and practitioners.
    Garlan Adams, the Chief Legal Officer at Crinetics Pharmaceuticals, directs all legal strategy, intellectual property protection, and corporate governance. Overseeing the legal framework for drug discovery, the Chief Legal Officer ensures that the company secures its innovative molecules and maintains compliance with regulatory standards. This leadership role involves managing complex contracts and mitigating risks associated with the development of therapies for endocrine diseases. By protecting the intellectual property that forms the core of the business, Garlan Adams directly impacts the long-term value for investors. Adams maintains a focus on legal excellence, ensuring that all partnerships and research activities operate within a secure framework. Through proactive legal guidance and strategic oversight, the Chief Legal Officer supports the company's ability to bring transformative therapies to market. Ultimately, Adams provides the legal foundation necessary for the organization to pursue its mission of improving patient lives.
    Garlan Adams

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    Frequently Asked Questions Regarding Crinetics Pharmaceuticals Top Executives and Leadership Team

    Who leads Crinetics Pharmaceuticals?
    Crinetics Pharmaceuticals is led by Tobin Schilke (Chief Financial Officer), along with executives such as Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management) and Adriana Cabre (Chief Human Resources Officer).
    Who is part of Crinetics Pharmaceuticals’s executive team?
    The executive team of Crinetics Pharmaceuticals includes leaders such as Tobin Schilke (Chief Financial Officer), Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management), Adriana Cabre (Chief Human Resources Officer) and other senior executives.
    How many executives does Crinetics Pharmaceuticals have?
    Crinetics Pharmaceuticals has 6 executives leading key business areas.
    What roles are included in Crinetics Pharmaceuticals’s leadership team?
    The leadership team of Crinetics Pharmaceuticals includes roles such as Chief Financial Officer, Chief of Staff To the Chief Operating Officer and Head of Alliance Management, Chief Human Resources Officer, Executive Assistant To the Chief Human Resources Officer, Affairs Operations Senior Director, Medical & Chief of Staff.