Crinetics Pharmaceuticals Executive and Leadership Team

September, 2026

Leadership Overview

Crinetics Pharmaceuticals has 6 executives leading key functions including financial strategy, human resources, operational management, medical affairs, and legal compliance.

Focused on advancing endocrine health, Crinetics Pharmaceuticals delivers transformative therapies through innovative drug discovery while maintaining a commitment to patient-centric disease control and long-term value creation for stakeholders.

Leadership Roles at Crinetics Pharmaceuticals

  • Chief Financial Officer - Tobin Schilke
  • Chief of Staff To the Chief Operating Officer and Head of Alliance Management - Niccole Le
  • Executive Assistant To the Chief Human Resources Officer - Natalie Berwald
  • Chief Human Resources Officer - Adriana Cabre
  • Affairs Operations Senior Director, Medical & Chief of Staff - Rafael Marino
  • Chief Legal Officer - Garlan Adams
  • Tobin Schilke - Chief Financial Officer

    Tobin Schilke, the Chief Financial Officer at Crinetics Pharmaceuticals, directs all fiscal planning and capital allocation strategies. Managing the financial health of the organization, the Chief Financial Officer oversees investor relations and ensures the availability of resources for the in-house R&D team. This leadership role involves rigorous oversight of budgetary frameworks to support the development of novel molecules targeting G protein-coupled receptors. By optimizing capital structure, Tobin Schilke directly impacts the ability of the company to advance its pipeline of endocrine therapies. Schilke maintains alignment with the board regarding long-term growth objectives and market expansion. Through precise financial modeling and risk assessment, the Chief Financial Officer secures the necessary funding to sustain drug discovery efforts. Ultimately, Schilke drives the fiscal discipline required to transform scientific innovation into tangible market value for shareholders and patients alike.
    Tobin Schilke

    Niccole Le - Chief of Staff To the Chief Operating Officer and Head of Alliance Management

    Niccole Le, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management at Crinetics Pharmaceuticals, manages cross-functional operations and external partnerships. Overseeing the integration of alliance activities, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management ensures that collaborative efforts with healthcare practitioners remain aligned with the core mission of endocrine disease control. This role involves architecting communication channels between the operations team and external stakeholders to accelerate the development of novel molecules. By facilitating strategic alignment, Niccole Le directly impacts the efficiency of the drug discovery pipeline. Le monitors project timelines and resource allocation to ensure operational excellence across all research phases. Through the management of complex alliances, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management secures the partnerships required to bring innovative therapies to market, ultimately supporting the company's goal of providing effective disease control for patients.

    Natalie Berwald - Executive Assistant To the Chief Human Resources Officer

    Natalie Berwald, the Executive Assistant To the Chief Human Resources Officer at Crinetics Pharmaceuticals, coordinates administrative workflows and operational support for the human capital division. Facilitating communication between the Chief Human Resources Officer and internal departments, the Executive Assistant To the Chief Human Resources Officer ensures the seamless execution of talent acquisition and organizational development initiatives. This role involves managing complex scheduling, preparing documentation for executive meetings, and tracking key performance indicators related to employee engagement. By streamlining daily operations, Natalie Berwald enables the leadership team to focus on building a high-performing culture dedicated to endocrine research. Berwald maintains strict confidentiality while managing sensitive personnel data and corporate records. Through proactive project management, the Executive Assistant To the Chief Human Resources Officer supports the broader mission of attracting top-tier scientific talent to the company, thereby strengthening the internal R&D capabilities necessary for developing transformative endocrine therapies.

    Adriana Cabre - Chief Human Resources Officer

    Adriana Cabre, the Chief Human Resources Officer at Crinetics Pharmaceuticals, designs and executes strategies for talent management and organizational culture. Leading the human resources department, the Chief Human Resources Officer ensures the company attracts and retains the specialized scientific talent required for G protein-coupled receptor research. This role involves developing compensation structures, performance management systems, and professional development programs that align with the company's R&D objectives. By fostering an environment of innovation, Adriana Cabre directly impacts the productivity of the drug discovery teams. Cabre collaborates with the executive leadership to ensure that organizational growth matches the pace of the clinical pipeline. Through the implementation of robust HR policies, the Chief Human Resources Officer supports the overall mission of delivering endocrine therapies to patients. Ultimately, Cabre drives the cultural initiatives that sustain the company's competitive advantage in the pharmaceutical industry, ensuring that every team member contributes effectively to the development of transformative molecules.
    Adriana Cabre

    Rafael Marino - Affairs Operations Senior Director, Medical & Chief of Staff

    Rafael Marino, the Affairs Operations Senior Director, Medical & Chief of Staff at Crinetics Pharmaceuticals, manages the operational infrastructure of the medical affairs department. Coordinating the flow of clinical data and medical insights, the Affairs Operations Senior Director, Medical & Chief of Staff ensures that the company maintains strong relationships with healthcare practitioners. This role involves overseeing the logistical aspects of medical communications and ensuring that scientific data regarding endocrine therapies reaches the medical community effectively. By streamlining these operations, Rafael Marino directly impacts the company's ability to address real-world clinical problems. Marino works closely with the R&D team to translate complex scientific findings into actionable medical information. Through the management of internal and external medical affairs workflows, the Affairs Operations Senior Director, Medical & Chief of Staff supports the broader goal of providing effective disease control. Ultimately, Marino ensures that the medical operations team functions with the precision required to advance the company's innovative pipeline.
    Garlan Adams, the Chief Legal Officer at Crinetics Pharmaceuticals, directs all legal strategy, intellectual property protection, and corporate compliance. Safeguarding the company's innovative drug discovery assets, the Chief Legal Officer manages the patent portfolio related to G protein-coupled receptors and novel endocrine molecules. This role involves navigating complex regulatory landscapes and ensuring that all clinical development activities adhere to global standards. By mitigating legal risks, Garlan Adams directly impacts the stability and growth of the company's pipeline. Adams collaborates with the executive team to structure partnerships and licensing agreements that expand the reach of the company's therapies. Through rigorous oversight of corporate governance, the Chief Legal Officer ensures that all business practices align with ethical and legal requirements. Ultimately, Adams secures the intellectual property and contractual foundations necessary for the company to deliver transformative therapies to patients, providing the legal framework that supports long-term market success.
    Garlan Adams

    Explore Leadership Teams in Business Services

    Frequently Asked Questions Regarding Crinetics Pharmaceuticals Top Executives and Leadership Team

    Who leads Crinetics Pharmaceuticals?
    Crinetics Pharmaceuticals is led by Tobin Schilke (Chief Financial Officer), along with executives such as Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management) and Natalie Berwald (Executive Assistant To the Chief Human Resources Officer).
    Who is part of Crinetics Pharmaceuticals’s executive team?
    The executive team of Crinetics Pharmaceuticals includes leaders such as Tobin Schilke (Chief Financial Officer), Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management), Natalie Berwald (Executive Assistant To the Chief Human Resources Officer) and other senior executives.
    How many executives does Crinetics Pharmaceuticals have?
    Crinetics Pharmaceuticals has 6 executives leading key business areas.
    What roles are included in Crinetics Pharmaceuticals’s leadership team?
    The leadership team of Crinetics Pharmaceuticals includes roles such as Chief Financial Officer, Chief of Staff To the Chief Operating Officer and Head of Alliance Management, Executive Assistant To the Chief Human Resources Officer, Chief Human Resources Officer, Affairs Operations Senior Director, Medical & Chief of Staff.