Crinetics Pharmaceuticals Executive and Leadership Team

August, 2026

Leadership Overview

Crinetics Pharmaceuticals has 6 executives leading key functions including finance, operations, human resources, and legal.

Driven by a commitment to patient well-being, Crinetics Pharmaceuticals develops essential therapies for endocrine diseases, aiming to simplify lives and provide effective disease control through collaboration with healthcare practitioners and by addressing critical market needs for investors.

Leadership Roles at Crinetics Pharmaceuticals

  • Chief Financial Officer - Tobin Schilke
  • Chief of Staff To the Chief Operating Officer and Head of Alliance Management - Niccole Le
  • Affairs Operations Senior Director, Medical & Chief of Staff - Rafael Marino
  • Executive Assistant To the Chief Human Resources Officer - Natalie Berwald
  • Chief Human Resources Officer - Adriana Cabre
  • Chief Legal Officer - Garlan Adams
  • Tobin Schilke - Chief Financial Officer

    Tobin Schilke, the Chief Financial Officer at Crinetics Pharmaceuticals, directs all financial operations and strategic fiscal planning. Overseeing budgeting, forecasting, and financial reporting, the Chief Financial Officer ensures robust financial health and supports the company's growth objectives. This leadership position involves managing capital allocation, investor relations, and risk management to build sustainable value. By optimizing financial strategies, Tobin Schilke directly contributes to the company's ability to fund the development of much-needed therapies for endocrine diseases. The Chief Financial Officer's oversight extends to ensuring compliance with financial regulations and driving efficiency across all fiscal activities, thereby reinforcing the company's market position and investor confidence.
    Tobin Schilke

    Niccole Le - Chief of Staff To the Chief Operating Officer and Head of Alliance Management

    Niccole Le, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management at Crinetics Pharmaceuticals, provides critical operational support and manages strategic partnerships. This dual role involves streamlining operations for the Chief Operating Officer while also spearheading alliance management initiatives to foster key collaborations. Overseeing the coordination of cross-functional projects, the Chief of Staff To the Chief Operating Officer and Head of Alliance Management ensures alignment with company goals and facilitates efficient execution of strategic plans. Niccole Le's responsibilities include driving the success of external partnerships, which are vital for developing and delivering therapies for endocrine diseases. The Head of Alliance Management ensures that collaborative efforts translate into tangible progress, supporting the company's mission to solve real problems for patients and healthcare practitioners.

    Rafael Marino - Affairs Operations Senior Director, Medical & Chief of Staff

    Rafael Marino, the Affairs Operations Senior Director, Medical & Chief of Staff at Crinetics Pharmaceuticals, leads critical medical operations and provides executive support. This senior role encompasses overseeing the strategic direction of medical affairs operations, ensuring alignment with the company's therapeutic development goals for endocrine diseases. As Chief of Staff, Rafael Marino facilitates communication and execution across various departments, enhancing operational efficiency and strategic implementation. The Affairs Operations Senior Director, Medical role involves managing key medical initiatives and ensuring compliance with industry standards. By driving effective medical operations, Marino supports the company's commitment to providing patients with therapies that offer effective disease control and simplicity. This leadership ensures that medical strategies directly address patient needs and support healthcare practitioners.

    Natalie Berwald - Executive Assistant To the Chief Human Resources Officer

    Natalie Berwald, the Executive Assistant To the Chief Human Resources Officer at Crinetics Pharmaceuticals, provides essential administrative and strategic support to the human resources function. This role is crucial for ensuring the smooth operation of HR initiatives that support the company's mission of developing therapies for endocrine diseases. The Executive Assistant To the Chief Human Resources Officer manages complex scheduling, coordinates meetings, and assists with the implementation of HR policies and programs. Natalie Berwald's contributions are vital for maintaining organizational efficiency and supporting the Chief Human Resources Officer in fostering a productive work environment. This support directly impacts the company's ability to attract and retain talent necessary for advancing its therapeutic development pipeline and meeting market needs.

    Adriana Cabre - Chief Human Resources Officer

    Adriana Cabre, the Chief Human Resources Officer at Crinetics Pharmaceuticals, directs all human capital strategies and organizational development initiatives. Overseeing talent acquisition, employee relations, and compensation and benefits, the Chief Human Resources Officer ensures a robust workforce capable of driving innovation in endocrine disease therapies. This leadership position involves cultivating a company culture that supports patient-centricity and operational excellence. By aligning HR strategies with business objectives, Adriana Cabre fosters an environment where employees can effectively develop much-needed therapies and address real market needs. The Chief Human Resources Officer's focus on talent management and employee engagement is critical for the company's long-term success and its ability to provide effective disease control and simplicity for patients.
    Adriana Cabre
    Garlan Adams, the Chief Legal Officer at Crinetics Pharmaceuticals, oversees all legal affairs and ensures corporate compliance. Directing legal strategy, risk management, and intellectual property protection, the Chief Legal Officer safeguards the company's interests as it develops therapies for endocrine diseases. This critical role involves advising the executive team and the board on legal matters, ensuring adherence to regulatory requirements, and managing litigation. By providing expert legal counsel, Garlan Adams supports the company's mission to solve real problems for patients and healthcare practitioners. The Chief Legal Officer's oversight is essential for navigating the complex regulatory landscape of the pharmaceutical industry, thereby building value for investors and ensuring the integrity of the company's operations.
    Garlan Adams

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    Frequently Asked Questions Regarding Crinetics Pharmaceuticals Top Executives and Leadership Team

    Who leads Crinetics Pharmaceuticals?
    Crinetics Pharmaceuticals is led by Tobin Schilke (Chief Financial Officer), along with executives such as Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management) and Rafael Marino (Affairs Operations Senior Director, Medical & Chief of Staff).
    Who is part of Crinetics Pharmaceuticals’s executive team?
    The executive team of Crinetics Pharmaceuticals includes leaders such as Tobin Schilke (Chief Financial Officer), Niccole Le (Chief of Staff To the Chief Operating Officer and Head of Alliance Management), Rafael Marino (Affairs Operations Senior Director, Medical & Chief of Staff) and other senior executives.
    How many executives does Crinetics Pharmaceuticals have?
    Crinetics Pharmaceuticals has 6 executives leading key business areas.
    What roles are included in Crinetics Pharmaceuticals’s leadership team?
    The leadership team of Crinetics Pharmaceuticals includes roles such as Chief Financial Officer, Chief of Staff To the Chief Operating Officer and Head of Alliance Management, Affairs Operations Senior Director, Medical & Chief of Staff, Executive Assistant To the Chief Human Resources Officer, Chief Human Resources Officer.