Broad Institute Executive and Leadership Team

June, 2026

Leadership Overview

Broad Institute has 8 executives leading key functions including operations, information technology, finance, strategy, human resources, communications, and advisory roles.

Driven by scientific discovery, Broad Institute is dedicated to advancing human health through groundbreaking research in genomics and the development of novel therapeutic strategies.

Leadership Roles at Broad Institute

  • Chief Financial Officer - Emme Handy
  • Chief Operating Officer - Daniel Shore
  • Chief Information Officer - Jennifer Nava
  • Chief of Staff & Senior Advisor - Alexander Ozonoff
  • Chief of Staff & To David R Liu Senior Advisor - Emily Botelho
  • Chief People Officer - Sarah Cox
  • Chief Communications Officer (Cco) - Lee McGuire
  • Senior Advisor To the Director - Ellen Law
  • Emme Handy - Chief Financial Officer

    Emme Handy, the Chief Financial Officer at Broad Institute, directs all financial planning, management, and reporting activities. This encompasses overseeing budgeting, forecasting, and fiscal strategy to support the institute's research into biology and new treatments for human diseases. Handy manages financial operations, ensuring compliance with regulatory standards and optimizing resource allocation for maximum research impact. The Chief Financial Officer's role is critical in securing funding and managing investments that fuel genomic research and therapeutic development. By providing strategic financial guidance, Emme Handy ensures the institute's long-term fiscal health and its capacity to pursue ambitious scientific goals. Handy's leadership guarantees that financial resources are effectively deployed to advance the institute's mission of understanding and treating human diseases.
    Emme Handy

    Daniel Shore - Chief Operating Officer

    Daniel Shore, the Chief Operating Officer at Broad Institute, directs the comprehensive operational framework supporting the institute's mission of biological research and disease treatment development. Overseeing critical infrastructure and resource allocation, Shore ensures the seamless execution of daily operations across all departments. This leadership role involves optimizing internal processes to enhance research efficiency and facilitate the discovery of new therapies. By managing facilities, administrative functions, and cross-departmental coordination, Daniel Shore drives the institute's capacity for innovation. The Chief Operating Officer's strategic focus extends to fostering an environment conducive to scientific breakthroughs, directly impacting the institute's ability to translate genomic insights into actionable treatments. Shore's oversight guarantees that the institute operates with maximum effectiveness, supporting its global research endeavors.
    Daniel Shore

    Jennifer Nava - Chief Information Officer

    Jennifer Nava, the Chief Information Officer at Broad Institute, architects and executes the institute's overarching information technology strategy. This involves ensuring robust, secure, and scalable digital infrastructure to support cutting-edge biological research and genomic analysis. Nava directs the management of data systems, cybersecurity protocols, and technological resources essential for discovering new therapies. The Chief Information Officer's responsibilities include driving digital transformation initiatives that enhance research capabilities and operational efficiency. By leading the IT department, Jennifer Nava ensures that the institute leverages advanced technologies to accelerate the pace of scientific discovery and the development of treatments for human diseases. Nava's strategic vision guarantees that the institute's technological foundation is state-of-the-art, enabling complex genomic research and data-driven therapeutic development.

    Alexander Ozonoff - Chief of Staff & Senior Advisor

    Alexander Ozonoff, the Chief of Staff & Senior Advisor at Broad Institute, provides strategic counsel and operational support to key leadership initiatives. This role involves facilitating cross-functional collaboration and driving the execution of critical projects aligned with the institute's research objectives in biology and disease treatment. Ozonoff enhances organizational effectiveness by streamlining communication channels and ensuring alignment across various departments focused on genomics and therapeutic development. The Chief of Staff & Senior Advisor's responsibilities include managing special projects and advising leadership on strategic priorities to accelerate scientific discovery. By acting as a key liaison, Alexander Ozonoff ensures that the institute's operational efforts are synchronized with its ambitious research agenda, contributing directly to the advancement of human health solutions.

    Emily Botelho - Chief of Staff & To David R Liu Senior Advisor

    Emily Botelho, the Chief of Staff & To David R Liu Senior Advisor at Broad Institute, provides critical strategic and operational support to the Director's office. This position involves managing key initiatives and ensuring the seamless execution of research strategies focused on biology and developing new treatments for human diseases. Botelho facilitates communication and coordination between research teams and leadership, driving progress in genomic research and therapeutic discovery. The Chief of Staff & To David R Liu Senior Advisor's role is integral to advancing the institute's mission by optimizing workflow and strategic alignment. By offering expert counsel and managing high-priority projects, Emily Botelho directly contributes to the institute's capacity for groundbreaking scientific advancements and the development of innovative health solutions.

    Sarah Cox - Chief People Officer

    Sarah Cox, the Chief People Officer at Broad Institute, leads the human resources strategy to cultivate a high-performing and supportive work environment. This role is essential for attracting, developing, and retaining top talent crucial for advancing biological research and developing new treatments for human diseases. Cox oversees all aspects of people operations, including talent acquisition, employee relations, compensation, and organizational development, ensuring alignment with the institute's mission. The Chief People Officer's strategic focus is on fostering a culture that champions innovation and collaboration in genomics and therapeutic discovery. By championing employee well-being and professional growth, Sarah Cox ensures the institute has the skilled workforce necessary to achieve its ambitious scientific goals and drive breakthroughs in human health.
    Sarah Cox

    Lee McGuire - Chief Communications Officer (Cco)

    Lee McGuire, the Chief Communications Officer (Cco) at Broad Institute, directs the institute's comprehensive communication strategies. This involves shaping and disseminating the institute's narrative around biological research, genomic discoveries, and the development of new treatments for human diseases. McGuire oversees public relations, internal communications, and digital outreach to effectively convey the impact of the institute's work. The Chief Communications Officer (Cco)'s role is vital in building and maintaining the institute's reputation and engaging stakeholders globally. By managing all facets of communication, Lee McGuire ensures that the institute's scientific advancements and mission are clearly understood, fostering support for its critical research endeavors and therapeutic development efforts.
    Lee McGuire

    Ellen Law - Senior Advisor To the Director

    Ellen Law, the Senior Advisor To the Director at Broad Institute, provides strategic guidance and expert counsel on critical initiatives. This role supports the institute's overarching mission to research biology and develop new treatments for human diseases through advanced genomics. Law collaborates with leadership to refine research strategies and enhance operational effectiveness, ensuring progress in therapeutic discovery. The Senior Advisor To the Director's responsibilities include offering insights on complex scientific and organizational challenges, contributing to the institute's capacity for innovation. By leveraging extensive experience, Ellen Law plays a key part in advancing the institute's objectives, ensuring that scientific endeavors are strategically aligned and effectively executed to achieve breakthroughs in human health.

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    Frequently Asked Questions Regarding Broad Institute Top Executives and Leadership Team

    Who leads Broad Institute?
    Broad Institute is led by Emme Handy (Chief Financial Officer), along with executives such as Daniel Shore (Chief Operating Officer) and Jennifer Nava (Chief Information Officer).
    Who is part of Broad Institute’s executive team?
    The executive team of Broad Institute includes leaders such as Emme Handy (Chief Financial Officer), Daniel Shore (Chief Operating Officer), Jennifer Nava (Chief Information Officer) and other senior executives.
    How many executives does Broad Institute have?
    Broad Institute has 8 executives leading key business areas.
    What roles are included in Broad Institute’s leadership team?
    The leadership team of Broad Institute includes roles such as Chief Financial Officer, Chief Operating Officer, Chief Information Officer, Chief of Staff & Senior Advisor, Chief of Staff & To David R Liu Senior Advisor.