Broad Institute Executive and Leadership Team

September, 2026

Leadership Overview

Broad Institute has 7 executives leading key functions including financial strategy, information technology, operational management, organizational leadership, human resources, communications, and strategic advisory.

Committed to advancing genomic research, Broad Institute accelerates the discovery of new therapies for human diseases through collaborative scientific innovation and rigorous data analysis.

Leadership Roles at Broad Institute

  • Chief Financial Officer - Emme Handy
  • Chief Operating Officer - Dan Shore
  • Chief Information Officer - Jennifer Hopkins
  • Chief of Staff & To David R Liu Senior Advisor - Emily Botelho
  • Chief People Officer - Sarah Cox
  • Chief Communications Officer (Cco) - Lee McGuire
  • Senior Advisor To the Director - Ellen Law
  • Emme Handy - Chief Financial Officer

    Emme Handy, the Chief Financial Officer at Broad Institute, directs all fiscal planning and resource allocation to support large-scale genomic research initiatives. Managing the financial health of the organization, the Chief Financial Officer oversees complex budgeting processes that enable scientists to pursue breakthroughs in human disease treatments. This leadership role involves maintaining rigorous compliance standards while optimizing funding streams for diverse research programs across North American operations. By aligning capital investments with long-term scientific goals, Emme Handy ensures the sustainability of the institute's mission. The Chief Financial Officer collaborates closely with the Board to provide transparent reporting on institutional performance. Through meticulous oversight of grants and operational expenditures, Handy secures the necessary financial foundation for ongoing innovation. This strategic management of resources directly impacts the ability of the institute to translate biological discoveries into tangible medical therapies for patients worldwide.
    Emme Handy

    Dan Shore - Chief Operating Officer

    Dan Shore, the Chief Operating Officer at Broad Institute, manages the daily administrative and operational functions that sustain the research environment. Overseeing facility logistics and institutional processes, the Chief Operating Officer ensures that laboratory teams operate within a framework of excellence and safety. This leadership role involves coordinating cross-departmental efforts to streamline the transition from basic biological research to clinical application. By optimizing internal workflows, Dan Shore enhances the productivity of the entire organization. The Chief Operating Officer collaborates with executive leadership to implement strategic initiatives that expand the reach of the institute's research programs. Through the management of complex operational requirements, Shore provides the stability needed for scientists to focus on finding new therapies for human diseases. This focus on operational efficiency directly supports the mission of the institute to improve global health outcomes through rigorous scientific inquiry.
    Dan Shore

    Jennifer Hopkins - Chief Information Officer

    Jennifer Hopkins, the Chief Information Officer at Broad Institute, architects the digital infrastructure required to process massive genomic datasets. Overseeing the integration of advanced computational tools, the Chief Information Officer ensures that researchers possess the high-performance computing capabilities necessary for identifying new disease therapies. This role involves managing cybersecurity protocols to protect sensitive biological data while facilitating seamless collaboration across global research networks. By modernizing data storage and analysis platforms, Jennifer Hopkins drives efficiency in the institute's R&D workflows. The Chief Information Officer works alongside scientific leadership to implement scalable technology solutions that accelerate the pace of discovery. Through the deployment of robust information systems, Hopkins supports the complex data requirements of modern biology. This technological leadership remains vital for maintaining the competitive edge of the institute in the rapidly evolving field of genomics and precision medicine.

    Emily Botelho - Chief of Staff & To David R Liu Senior Advisor

    Emily Botelho, the Chief of Staff & To David R Liu Senior Advisor at Broad Institute, coordinates strategic priorities and facilitates communication between executive leadership and research teams. Overseeing the execution of key initiatives, the Chief of Staff & To David R Liu Senior Advisor ensures that organizational goals remain aligned with the broader mission of discovering new therapies for human diseases. This role involves managing complex projects that require cross-functional collaboration across the institute. By providing high-level advisory support, Emily Botelho enables the leadership team to focus on critical scientific and administrative decisions. The Chief of Staff & To David R Liu Senior Advisor acts as a central point of contact for internal and external stakeholders, ensuring clarity and consistency in institutional messaging. Through the management of strategic workflows, Botelho drives the successful implementation of programs that advance the institute's impact on global medical research.

    Sarah Cox - Chief People Officer

    Sarah Cox, the Chief People Officer at Broad Institute, directs talent acquisition, professional development, and organizational culture initiatives. Overseeing the recruitment of world-class scientists and administrative staff, the Chief People Officer ensures that the institute attracts the expertise required to push the boundaries of genomic research. This leadership role involves designing programs that foster an inclusive and collaborative environment, which remains essential for scientific innovation. By implementing effective human capital strategies, Sarah Cox supports the growth and retention of a diverse workforce. The Chief People Officer works with department heads to align personnel needs with the long-term research objectives of the organization. Through the cultivation of a high-performance culture, Cox enables the institute to maintain its position as a leader in the field of human disease research. This focus on people and culture directly contributes to the success of the institute's mission.
    Sarah Cox

    Lee McGuire - Chief Communications Officer (Cco)

    Lee McGuire, the Chief Communications Officer (Cco) at Broad Institute, manages the public image and institutional messaging regarding genomic research and therapeutic breakthroughs. Overseeing external relations and media strategy, the Chief Communications Officer (Cco) ensures that the impact of the institute's work reaches the scientific community, policymakers, and the general public. This role involves crafting narratives that highlight the importance of biological research in finding new treatments for human diseases. By directing communication campaigns, Lee McGuire builds awareness and support for the institute's mission. The Chief Communications Officer (Cco) collaborates with leadership to maintain transparency and engagement with stakeholders across the global research landscape. Through the strategic dissemination of information, McGuire strengthens the reputation of the institute as a hub for innovation. This focus on effective communication ensures that the value of the institute's research is clearly understood and recognized.
    Lee McGuire

    Ellen Law - Senior Advisor To the Director

    Ellen Law, the Senior Advisor To the Director at Broad Institute, provides strategic guidance on institutional direction and long-term research planning. Overseeing the development of high-level initiatives, the Senior Advisor To the Director ensures that the institute remains at the forefront of genomic science and therapeutic discovery. This role involves analyzing market trends and scientific advancements to inform the decision-making process of the leadership team. By offering expert counsel, Ellen Law helps shape the strategic vision of the organization. The Senior Advisor To the Director works closely with the Director to address complex challenges and identify new opportunities for growth in the field of human disease research. Through the provision of strategic insights, Law supports the alignment of institutional resources with the most promising areas of biological inquiry. This advisory role remains critical for maintaining the focus and impact of the institute's research programs.

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    Frequently Asked Questions Regarding Broad Institute Top Executives and Leadership Team

    Who leads Broad Institute?
    Broad Institute is led by Emme Handy (Chief Financial Officer), along with executives such as Dan Shore (Chief Operating Officer) and Jennifer Hopkins (Chief Information Officer).
    Who is part of Broad Institute’s executive team?
    The executive team of Broad Institute includes leaders such as Emme Handy (Chief Financial Officer), Dan Shore (Chief Operating Officer), Jennifer Hopkins (Chief Information Officer) and other senior executives.
    How many executives does Broad Institute have?
    Broad Institute has 7 executives leading key business areas.
    What roles are included in Broad Institute’s leadership team?
    The leadership team of Broad Institute includes roles such as Chief Financial Officer, Chief Operating Officer, Chief Information Officer, Chief of Staff & To David R Liu Senior Advisor, Chief People Officer.