Agios Executive and Leadership Team

July, 2026

Leadership Overview

Agios has 4 executives leading key functions including finance, human resources, legal, and medical strategy.

Driven by scientific innovation, Agios is dedicated to discovering and developing transformative medicines for patients with rare genetic diseases, focusing on the critical role of cellular metabolism.

Leadership Roles at Agios

  • Chief Financial Officer - Cecilia Jones
  • Chief People Officer - Ellen Lopresti
  • Chief Legal Officer - James Burns
  • Chief Medical Officer & Executive Vice President - Sarah Gheuens
  • Cecilia Jones - Chief Financial Officer

    Cecilia Jones, the Chief Financial Officer at Agios, directs all financial operations and strategic fiscal planning. Overseeing budgeting, forecasting, and capital allocation, Jones ensures robust financial health to support the company's drug development pipeline. This leadership role involves managing investor relations and communicating financial performance to stakeholders. By optimizing resource deployment, Cecilia Jones directly supports the advancement of novel therapies like PYRUKYND and pipeline candidates targeting rare diseases. The Chief Financial Officer's strategic guidance is crucial for sustained growth and market positioning in the biopharmaceutical sector, ensuring financial stability for ongoing research and development initiatives across the United States.

    Ellen Lopresti - Chief People Officer

    Ellen Lopresti, the Chief People Officer at Agios, architects the company's human capital strategy and cultivates a high-performance culture. Overseeing talent acquisition, development, and employee engagement, Lopresti ensures a skilled and motivated workforce dedicated to Agios's mission. This executive position involves fostering an inclusive environment that supports innovation in drug discovery and development. By championing organizational development, Ellen Lopresti directly contributes to the effective execution of strategies for bringing life-changing medicines to patients. The Chief People Officer's focus on people operations is fundamental to Agios's success in the competitive biopharmaceutical landscape, driving employee retention and fostering collaboration across all departments in Cambridge, Massachusetts.
    James Burns, the Chief Legal Officer at Agios, provides strategic legal counsel and oversees all corporate governance matters. Directing the legal department, Burns manages intellectual property, regulatory compliance, and litigation, safeguarding the company's assets and interests. This critical role ensures adherence to stringent pharmaceutical regulations across the United States. By mitigating legal risks, James Burns directly supports the advancement of Agios's innovative therapies, including PYRUKYND and pipeline candidates. The Chief Legal Officer's expertise is essential for navigating the complex legal and regulatory frameworks inherent in drug development and commercialization, ensuring the company operates with integrity and compliance.

    Sarah Gheuens - Chief Medical Officer & Executive Vice President

    Sarah Gheuens, the Chief Medical Officer & Executive Vice President at Agios, spearheads clinical development and medical affairs strategies. Overseeing the design and execution of clinical trials for novel therapeutics, Gheuens drives the advancement of medicines like PYRUKYND and pipeline assets targeting rare genetic diseases. This senior leadership position involves translating scientific insights into effective patient treatments and ensuring medical excellence. By guiding clinical research, Sarah Gheuens directly impacts the successful progression of drug candidates through regulatory pathways. The Chief Medical Officer's deep medical expertise is paramount to Agios's mission of delivering transformative therapies, shaping the future of treatment for hemolytic anemias and other metabolic disorders.

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    Frequently Asked Questions Regarding Agios Top Executives and Leadership Team

    Who leads Agios?
    Agios is led by Cecilia Jones (Chief Financial Officer), along with executives such as Ellen Lopresti (Chief People Officer) and James Burns (Chief Legal Officer).
    Who is part of Agios’s executive team?
    The executive team of Agios includes leaders such as Cecilia Jones (Chief Financial Officer), Ellen Lopresti (Chief People Officer), James Burns (Chief Legal Officer) and other senior executives.
    How many executives does Agios have?
    Agios has 4 executives leading key business areas.
    What roles are included in Agios’s leadership team?
    The leadership team of Agios includes roles such as Chief Financial Officer, Chief People Officer, Chief Legal Officer, Chief Medical Officer & Executive Vice President.