Where is McKesson Headquarters?
Main Office Address and Global Locations

The official headquarters of McKesson is located at 6555 State Highway 161, Irving, Texas, United States. This facility is situated within a prominent commercial corridor in the Dallas-Fort Worth metropolitan area, providing access to major transportation infrastructure. The site functions as a large-scale corporate office environment designed to accommodate administrative, executive, and operational staff members. The architecture reflects a standard professional office layout, prioritizing functional workspaces and meeting areas to facilitate daily business activities. As a significant corporate site, the building serves as the primary base for the company's leadership teams and administrative departments that oversee its diverse healthcare segments. This location acts as the strategic core for the company's North American and international operations, housing key departments responsible for pharmaceutical distribution and medical-surgical solutions. By centralizing executive management and corporate governance in Irving, the company ensures consistent oversight of its four core business segments, including oncology and prescription technology services. The facility supports the broader organizational mission by providing the necessary infrastructure for high-level decision-making and long-term planning. As the operational heart of the enterprise, this office coordinates the complex logistics and supply chain requirements that define the company's role in the global healthcare market. It remains the primary point of contact for corporate inquiries and the main facility for managing the company's extensive network of regional offices.