What is System?
System is dedicated to creating knowledge infrastructure that revolutionizes decision-making by shifting from siloed operations to systemic integration, with an initial focus on the healthcare industry. Its proprietary APIs are currently utilized by prominent healthcare providers across the US and Europe to enhance groundbreaking clinical decision support systems (CDSS). At the heart of System's innovation is the System Graph, a patented, large-scale statistical model of the world, conceptualized as a single interconnected system. This graph is continuously updated with information from trusted evidence sources, reflecting the company's commitment to data integrity and comprehensive understanding.
How much funding has System raised?
System has raised a total of $16.5M across 2 funding rounds:
Series A
$10M
Unspecified
$6.5M
Series A (2021): $10M with participation from Acrew Capital Management
Unspecified (2025): $6.5M led by The Wellcome Trust
Key Investors in System
The Wellcome Trust
The Wellcome Trust is an independent global charitable foundation based in London that supports discovery research and tackles urgent health challenges, funding science, policy, and public engagement to improve health for people everywhere through grants, partnerships, and advocacy.
Acrew Capital Management
Acrew Capital is a venture capital firm focused on long-term partnerships and deep conviction in investment decisions, supporting early-stage to growth-stage companies. They emphasize multidisciplinary and multigenerational teams, emotional intelligence, and diverse perspectives to foster resilience and strategic thinking.
What's next for System?
With the recent major strategic investment and substantial overall capital, System is poised for accelerated expansion and further development of its knowledge infrastructure. The company's focus on transforming decision-making in healthcare through its System Graph technology positions it for significant impact. Future endeavors will likely involve scaling its API integrations with more healthcare providers and potentially exploring applications in other sectors that require sophisticated, system-level decision support. The strategic backing suggests a focus on enhancing its patented technology and broadening its market reach, solidifying its position as a leader in applied systems thinking.
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