How Much Did Profluent Bio Raise?
Funding & Key Investors

Profluent Bio, an AI-first protein design company, has secured significant enterprise-level funding, with its most recent strategic investment amounting to $106M. This latest capital infusion adds to the company's substantial total funding of $141M, underscoring its rapid growth and the market's confidence in its innovative approach to protein design.

What is Profluent Bio?

Profluent Bio
Business ServicesResearch & Development

Founded in 2022 and headquartered in Berkeley, CA, Profluent Bio is at the forefront of revolutionizing biomedicine through advanced AI. The company specializes in developing deep generative models to design and validate novel, functional proteins. This cutting-edge technology positions Profluent Bio as a key player in the synthetic biology and AI-driven drug discovery sectors, aiming to accelerate the development of new therapeutics and biotechnological solutions.

How much funding has Profluent Bio raised?

Profluent Bio has raised a total of $141M across 2 funding rounds:

2024

Other Financing Round

$35M

2025

Other Financing Round

$106M

Other Financing Round (2024): $35M with participation from Insight Partners, Air Street Capital, and Spark Capital

Other Financing Round (2025): $106M led by Insight Partners, Bezos Expeditions, Altimeter Capital, and Spark Capital

Key Investors in Profluent Bio

Insight Partners

Insight Partners is a global venture capital and private equity firm that invests in high-growth software and technology companies. It provides capital and hands-on operational support to help businesses scale from early stage to IPO, focusing on enterprise software, SaaS, and internet platforms.

Bezos Expeditions

Bezos Expeditions is an investment firm founded by Jeff Bezos that focuses on a diverse range of sectors including technology, healthcare, and space exploration. The firm is known for its strategic investments in innovative companies such as Airbnb, Uber, and Twitter.

Altimeter Capital

Altimeter Capital is an investment firm that partners with technology companies from early growth through public markets. It manages concentrated, long term portfolios and works closely with founders and teams to support product, strategy and durable value creation.

What's next for Profluent Bio?

With this major strategic investment, Profluent Bio is poised for accelerated scaling and further development of its AI-driven protein design platform. The substantial capital infusion is expected to fuel research and development initiatives, expand its team of AI and biotech experts, and enhance its capabilities in designing and validating functional proteins. This funding round signals a strong trajectory for the company as it aims to make significant advancements in revolutionizing biomedicine.

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Frequently Asked Questions Regarding Profluent Bio Financial Insights

What are the most recent funding rounds that Profluent Bio has completed, and what were the funding rounds?
Profluent Bio has recently completed 2 funding rounds: Other Financing Round on Nov 19, 2025, Other Financing Round on Mar 20, 2024.
What is the total amount of funding Profluent Bio has raised to date?
Profluent Bio has raised a total of $141M in funding to date.
How many funding rounds has Profluent Bio completed?
Profluent Bio has completed 2 funding rounds.
How much funding did Profluent Bio raise in its most recent funding round?
Profluent Bio raised $106M in its most recent funding round.
Who are the lead investors in Profluent Bio's latest funding round?
The lead investor in Profluent Bio's latest funding round was Insight Partners. To access investor data and explore similar companies, sign up for ZoomInfo.
Which was the largest funding round in Profluent Bio's history?
The largest funding round in Profluent Bio's history was $106M.
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