How Much Did Affect Raise?
Funding & Key Investors

Affect, a prominent player in the digital health sector, has successfully secured a major strategic investment, bringing its total capital raised to $50M. This latest infusion of $26M marks a significant milestone in the company's evolution, signaling robust investor confidence in its mission to revolutionize the treatment of substance use and mental health disorders. By leveraging a sophisticated, smartphone-delivered virtual clinic, Affect continues to bridge critical gaps in behavioral health accessibility.

The company's funding trajectory reflects a clear path of maturation, beginning with its initial seed round and progressing through subsequent institutional financing rounds. This latest capital injection positions Affect to further scale its evidence-based care models, which integrate contingency management, structured counseling, and AI-driven clinical decision support systems to serve diverse patient populations across Medicaid, Medicare, and commercial health plans.

What is Affect?

Affect
Hospitals & Physicians ClinicsMedical & Surgical HospitalsHealthcare Services

Affect Therapeutics operates at the intersection of technology and clinical care, providing a comprehensive virtual platform designed to address the complexities of substance use and mental health disorders. The company's proprietary model utilizes an AI-powered clinical decision support system to facilitate real-time triage, crisis intervention, and personalized treatment pathways. By partnering with payers and health systems, Affect ensures that its evidence-based interventions are both scalable and affordable, effectively modernizing the delivery of behavioral health services in an increasingly digital-first healthcare landscape.

How much funding has Affect raised?

Affect has raised a total of $50M across 3 funding rounds:

2021

Seed

$1M

2023

Series A

$23M

2025

Series B

$26M

Seed (2021): $1M with participation from AlleyCorp companies

Series A (2023): $23M led by ARTIS Ventures

Series B (2025): $26M supported by City Light Capital, LifeArc Ventures, Allumia Ventures, and ARTIS Ventures

Key Investors in Affect

ARTIS Ventures

A dedicated venture capital fund focused on Tech Bio and Health, investing in innovative data-driven life sciences companies that aim to enhance human health and wellness through AI and engineering.

City Light Capital

A venture capital firm specializing in double bottom line investing, supporting early-stage companies that provide strong financial returns alongside positive contributions to society and the environment.

LifeArc Ventures

The venture arm of a medical research charity, focusing on science-led companies that aim to positively impact patient lives through innovative therapeutics and HealthTech solutions.

What's next for Affect?

With this latest round of financing, Affect is well-positioned to accelerate its market penetration and enhance its technological infrastructure. The strategic focus will likely center on expanding its footprint within Medicaid and employer-sponsored health plans, where the demand for scalable, high-quality behavioral health solutions remains acute. Furthermore, the integration of advanced AI capabilities will remain a core priority, enabling the company to refine its triage algorithms and improve patient outcomes through more precise, data-informed clinical insights. As the company scales, its ability to maintain high-touch, personalized care while managing large-scale patient populations will be the primary metric for its continued success in the competitive HealthTech arena.

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Frequently Asked Questions Regarding Affect Financial Insights

What are the most recent funding rounds that Affect has completed, and what were the funding rounds?
Affect has recently completed 3 funding rounds: Series B on Nov 4, 2025, Series A on Jul 11, 2023, Seed on Apr 20, 2021.
What is the total amount of funding Affect has raised to date?
Affect has raised a total of $50M in funding to date.
How many funding rounds has Affect completed?
Affect has completed 3 funding rounds.
How much funding did Affect raise in its most recent funding round?
Affect raised $26M in its most recent funding round.
Who are the lead investors in Affect's latest funding round?
The lead investor in Affect's latest funding round was City Light Capital. To access investor data and explore similar companies, sign up for ZoomInfo.
Which was the largest funding round in Affect's history?
The largest funding round in Affect's history was $26M.
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