Vertex Executive and Leadership Team

July, 2026

Leadership Overview

Vertex has 10 executives leading key functions including strategy, research, operations, and human resources.

Driven by a commitment to scientific innovation, Vertex is dedicated to developing transformative medicines for serious diseases with significant unmet medical needs, impacting patients globally through advanced biotechnology.

Leadership Roles at Vertex

  • Chief Executive Officer & President - Md Reshma Kewalramani
  • Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office - Gina LaCorcia
  • Head Chief Operating Officer, Site (Seattle) - Christina Yi
  • Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals - Stephanie Franklin (she/her/hers)
  • Toxicology Research Senior Scientist & Chief Revenue Officer, Study Monitor - Colleen O'Brien
  • Senior Principal Scientist and Chief Revenue Officer Monitor and Associate Director - Sazzad Hussain
  • Head To of Cell & Gene Therapy Research Chief of Staff - Adila Crimi
  • Director, Chief of Staff, U. S. Commercial - Olivia Green
  • Director, Chief of Staff - Global Commercial Strategy - Moira Scanlon
  • Executive Assistant To Chief Human Resources Officer - Amy Longwell
  • Md Reshma Kewalramani - Chief Executive Officer & President

    Md Reshma Kewalramani, the Chief Executive Officer & President at Vertex, directs the company's overarching strategy and operational execution. This leadership role involves guiding Vertex's mission to develop and commercialize medicines for serious diseases with significant unmet medical needs. Kewalramani oversees the advancement of research programs in areas such as kidney disease, type 1 diabetes, and myotonic dystrophy, ensuring alignment with the company's commitment to patient well-being. Driving innovation across the organization, the Chief Executive Officer & President ensures that Vertex maintains its position at the forefront of biotechnology. This executive's focus extends to fostering a culture of scientific excellence and strategic growth, impacting patient outcomes worldwide. By championing new therapeutic approaches, Md Reshma Kewalramani solidifies Vertex's dedication to addressing critical health challenges through groundbreaking science and patient-centric development.
    Md Reshma Kewalramani

    Gina LaCorcia - Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office

    Gina LaCorcia, the Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office at Vertex, provides critical strategic support to the Chief Executive Officer and leads the program office for disease strategy. This multifaceted role ensures that Vertex's research and development efforts are precisely aligned with the company's mission to address significant unmet medical needs. LaCorcia facilitates high-level strategic planning, oversees key cross-functional initiatives, and ensures effective communication across the executive team and research divisions. Managing the Disease Strategy Team Program Office, the Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office drives the focused development of therapies for critical illnesses. By enhancing strategic clarity and operational efficiency, Gina LaCorcia significantly contributes to Vertex's ability to bring life-changing medicines to patients globally.

    Christina Yi - Head Chief Operating Officer, Site (Seattle)

    Christina Yi, the Head Chief Operating Officer, Site (Seattle) at Vertex, spearheads the operational management and strategic development of the company's Seattle-based facilities and research initiatives. This executive role focuses on optimizing site operations to support Vertex's core mission of developing medicines for serious diseases. Yi directs the integration of cutting-edge research and development activities within the Seattle hub, ensuring seamless collaboration across scientific teams. Overseeing critical infrastructure and resource allocation, the Head Chief Operating Officer, Site (Seattle) drives efficiency and innovation within the site's operations. By fostering a dynamic research environment, Christina Yi ensures that the Seattle location significantly contributes to Vertex's global pipeline advancement, particularly in areas like genetic disorders and pain management, reinforcing the company's commitment to patient impact.

    Stephanie Franklin (she/her/hers) - Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals

    Stephanie Franklin (she/her/hers), the Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals at Vertex, architects the human capital strategy essential for driving scientific innovation and operational excellence. This critical role involves cultivating a high-performance culture that attracts, develops, and retains top talent across all functions, from research and development to commercial operations. Franklin ensures that Vertex's workforce is equipped with the skills and resources necessary to tackle complex medical challenges and advance the company's pipeline of transformative medicines. Overseeing global HR initiatives, the Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals champions employee engagement and fosters an inclusive environment that supports the company's mission. By aligning human resources policies with strategic business objectives, Stephanie Franklin (she/her/hers) directly contributes to Vertex's ability to deliver life-changing therapies to patients worldwide, reinforcing the organization's commitment to scientific advancement and patient care.

    Colleen O'Brien - Toxicology Research Senior Scientist & Chief Revenue Officer, Study Monitor

    Colleen O'Brien, the Toxicology Research Senior Scientist & Chief Revenue Officer, Study Monitor at Vertex, leads critical toxicology research initiatives and oversees study monitoring to ensure the safety and efficacy of Vertex's therapeutic candidates. This dual-focused role involves rigorous scientific investigation into potential drug effects while also ensuring the financial integrity and strategic alignment of revenue-generating activities related to research services. O'Brien's expertise in toxicology directly supports the development of medicines for serious diseases, contributing to Vertex's mission of addressing unmet medical needs. The Toxicology Research Senior Scientist & Chief Revenue Officer, Study Monitor ensures adherence to stringent regulatory standards and monitors key performance indicators for research programs. By integrating scientific depth with financial oversight, Colleen O'Brien advances Vertex's commitment to delivering safe and effective treatments to patients globally.
    Colleen O'Brien

    Sazzad Hussain - Senior Principal Scientist and Chief Revenue Officer Monitor and Associate Director

    Sazzad Hussain, the Senior Principal Scientist and Chief Revenue Officer Monitor and Associate Director at Vertex, drives scientific advancement in key research areas while ensuring the effective monitoring of revenue-generating projects. This role integrates deep scientific expertise with financial oversight, crucial for advancing Vertex's mission of developing medicines for serious diseases. Hussain leads complex research initiatives, contributing to the company's pipeline in areas such as sickle cell disease and beta thalassemia. The Senior Principal Scientist and Chief Revenue Officer Monitor and Associate Director also ensures that research-related revenue streams are managed efficiently and strategically aligned with corporate goals. By bridging scientific discovery with financial acumen, Sazzad Hussain plays a vital part in Vertex's commitment to bringing transformative therapies to patients worldwide, reinforcing the company's dedication to innovation and patient outcomes.
    Sazzad Hussain

    Adila Crimi - Head To of Cell & Gene Therapy Research Chief of Staff

    Adila Crimi, the Head To of Cell & Gene Therapy Research Chief of Staff at Vertex, orchestrates the strategic direction and operational execution for Vertex's cutting-edge cell and gene therapy research programs. This leadership position is pivotal in advancing the company's mission to develop transformative medicines for serious genetic disorders. Crimi ensures seamless coordination between research teams, operational functions, and executive leadership, facilitating the efficient progression of novel therapeutic candidates. Overseeing key strategic initiatives within cell and gene therapy research, the Head To of Cell & Gene Therapy Research Chief of Staff drives innovation and operational excellence. By aligning research efforts with Vertex's broader objectives, Adila Crimi significantly contributes to the company's commitment to addressing significant unmet medical needs and improving patient lives through advanced biotechnology.

    Olivia Green - Director, Chief of Staff, U. S. Commercial

    Olivia Green, the Director, Chief of Staff, U. S. Commercial at Vertex, directs strategic initiatives and operational enhancements within the United States commercial division. This role is critical in ensuring that Vertex's innovative therapies reach patients effectively across the U.S. market. Green collaborates closely with commercial leadership to optimize market access, sales strategies, and patient support programs, directly supporting the company's mission to serve those with serious diseases. Overseeing key projects and cross-functional alignment, the Director, Chief of Staff, U. S. Commercial drives efficiency and impact in commercial operations. By enhancing the reach and effectiveness of Vertex's commercial efforts, Olivia Green ensures that the company's life-changing medicines are accessible to the patients who need them most, reinforcing Vertex's commitment to global health.

    Moira Scanlon - Director, Chief of Staff - Global Commercial Strategy

    Moira Scanlon, the Director, Chief of Staff - Global Commercial Strategy at Vertex, drives the strategic planning and execution of Vertex's worldwide commercial initiatives. This executive function is essential for ensuring that Vertex's portfolio of medicines for serious diseases achieves maximum global impact. Scanlon collaborates with international commercial teams to refine market strategies, enhance product launches, and optimize patient access across diverse regions. Overseeing critical global commercial projects, the Director, Chief of Staff - Global Commercial Strategy ensures cohesive strategy implementation and operational effectiveness. By strengthening Vertex's global commercial presence, Moira Scanlon directly contributes to the company's mission of delivering transformative therapies to patients around the world, underscoring a commitment to broad patient care and scientific leadership.

    Amy Longwell - Executive Assistant To Chief Human Resources Officer

    Amy Longwell, the Executive Assistant To Chief Human Resources Officer at Vertex, provides essential administrative and operational support to the Chief Human Resources Officer, facilitating the smooth execution of human capital strategies. This role is integral to maintaining the efficiency of HR operations, which are crucial for supporting Vertex's mission of developing medicines for serious diseases. Longwell manages complex scheduling, coordinates key meetings, and supports the implementation of HR initiatives designed to foster a productive and engaged workforce. By ensuring the Chief Human Resources Officer can focus on strategic priorities, the Executive Assistant To Chief Human Resources Officer contributes indirectly to Vertex's overall success. This support enables the HR function to effectively manage talent and cultivate a culture that drives scientific innovation and patient-centric development across the organization.

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    Frequently Asked Questions Regarding Vertex Top Executives and Leadership Team

    Who leads Vertex?
    Vertex is led by Md Reshma Kewalramani (Chief Executive Officer & President), along with executives such as Gina LaCorcia (Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office) and Christina Yi (Head Chief Operating Officer, Site (Seattle)).
    Who is part of Vertex’s executive team?
    The executive team of Vertex includes leaders such as Md Reshma Kewalramani (Chief Executive Officer & President), Gina LaCorcia (Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office), Christina Yi (Head Chief Operating Officer, Site (Seattle)) and other senior executives.
    How many executives does Vertex have?
    Vertex has 10 executives leading key business areas.
    What roles are included in Vertex’s leadership team?
    The leadership team of Vertex includes roles such as Chief Executive Officer & President, Vice President, Chief of Staff To the Chief Executive Officer and Head of the Disease Strategy Team Program Office, Head Chief Operating Officer, Site (Seattle), Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals, Toxicology Research Senior Scientist & Chief Revenue Officer, Study Monitor.