Vertex Executive and Leadership Team

May, 2026

Leadership Overview

Vertex has 10 executives leading key functions including strategy, technology, operations, marketing, and human resources.

Driven by innovation, Vertex is dedicated to discovering, developing, and commercializing transformative medicines for serious diseases, impacting global health through scientific advancement.

Leadership Roles at Vertex

  • Chief Executive Officer & President - Md Reshma Kewalramani
  • Head Chief Operating Officer, Site (Seattle) - Christina Yi
  • Chief Technology Officer - Wayne Gombotz
  • Director, Chief of Staff, North America Commercial - Olivia Green
  • Chief of Staff & Director - Katie Noon
  • Director, Chief of Staff To the Head of Medical Affairs - Rashmi Sarnaik
  • Senior Director, Chief of Staff To the Chief Regulatory and Quality Officer - Erin Connors
  • Executive Assistant To Stephanie Franklin, SVP & Chief Human Resources Officer - Amy Longwell
  • Senior Vice President and Chief Marketing Officer - Robert Kauffman
  • Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals - Stephanie Franklin (she/her/hers)
  • Md Reshma Kewalramani - Chief Executive Officer & President

    Md Reshma Kewalramani, the Chief Executive Officer & President at Vertex, directs the company's overarching strategy and operational execution. Driving the discovery, development, and commercialization of transformative medicines for serious diseases, Kewalramani ensures alignment with Vertex's mission. This leadership role involves guiding research initiatives, clinical trial progression, and market access strategies across global operations. By fostering a culture of scientific rigor and innovation, Md Reshma Kewalramani advances the company's pipeline and strengthens its position in the biotechnology sector. The focus remains on delivering breakthrough therapies to patients worldwide, managing key stakeholder relationships, and ensuring sustainable growth for the organization.
    Md Reshma Kewalramani

    Christina Yi - Head Chief Operating Officer, Site (Seattle)

    Christina Yi, the Head Chief Operating Officer, Site (Seattle) at Vertex, directs site operations and drives operational excellence at the Seattle location. Overseeing all aspects of facility management, research support, and local workforce coordination, Yi ensures the Seattle site functions efficiently. This leadership role involves managing resources, implementing operational improvements, and fostering a collaborative environment to support Vertex's research objectives. By optimizing site-specific operations, Christina Yi contributes directly to the company's overall productivity and scientific advancement. The focus is on ensuring the Seattle facility effectively supports Vertex's mission to discover and develop transformative medicines.

    Wayne Gombotz - Chief Technology Officer

    Wayne Gombotz, the Chief Technology Officer at Vertex, architects the company's technological infrastructure and digital transformation initiatives. Overseeing all aspects of information technology and data science, Gombotz ensures robust systems support Vertex's drug discovery and development processes. This leadership position involves managing cybersecurity, cloud computing, and advanced analytics to accelerate research timelines. By implementing cutting-edge technological solutions, Wayne Gombotz enhances operational efficiency and data integrity across the organization. The CTO's responsibilities extend to fostering technological innovation, driving digital collaboration, and safeguarding sensitive research data, all critical to Vertex's scientific objectives and market competitiveness.

    Olivia Green - Director, Chief of Staff, North America Commercial

    Olivia Green, the Director, Chief of Staff, North America Commercial at Vertex, spearheads strategic initiatives and operational alignment within the commercial division for the North American market. Managing cross-functional projects and enhancing communication flows, Green supports the execution of commercial strategies. This role involves optimizing sales force effectiveness, market penetration, and customer engagement across the region. By driving key operational improvements, Olivia Green ensures the commercial team effectively delivers Vertex's innovative therapies to patients. The focus is on enhancing market access, supporting product launches, and achieving commercial targets within the dynamic North American pharmaceutical landscape.

    Katie Noon - Chief of Staff & Director

    Katie Noon, the Chief of Staff & Director at Vertex, provides strategic support and drives operational excellence across key organizational functions. Coordinating critical projects and facilitating executive decision-making, Noon ensures seamless execution of company-wide initiatives. This position involves bridging communication between departments, managing strategic planning processes, and enhancing overall organizational efficiency. By streamlining operations and fostering collaboration, Katie Noon directly contributes to Vertex's ability to advance its drug discovery and development programs. The role demands a comprehensive understanding of the biotechnology landscape and a commitment to driving impactful change throughout the organization.

    Rashmi Sarnaik - Director, Chief of Staff To the Head of Medical Affairs

    Rashmi Sarnaik, the Director, Chief of Staff To the Head of Medical Affairs at Vertex, enhances the strategic direction and operational efficiency of the Medical Affairs division. Coordinating critical projects and ensuring alignment with global medical strategies, Sarnaik supports the advancement of Vertex's therapeutic programs. This role involves managing key initiatives, facilitating cross-functional collaboration, and optimizing resource allocation within Medical Affairs. By driving operational improvements, Rashmi Sarnaik ensures the effective dissemination of scientific information and support for Vertex's innovative medicines. The focus remains on strengthening the medical affairs function to support patient access and scientific exchange.

    Erin Connors - Senior Director, Chief of Staff To the Chief Regulatory and Quality Officer

    Erin Connors, the Senior Director, Chief of Staff To the Chief Regulatory and Quality Officer at Vertex, drives strategic alignment and operational effectiveness within regulatory and quality functions. Managing critical projects and ensuring adherence to global compliance standards, Connors supports the integrity of Vertex's drug development and manufacturing processes. This position involves coordinating regulatory submissions, quality assurance initiatives, and cross-departmental communication to maintain the highest standards. By optimizing operational workflows, Erin Connors ensures Vertex meets stringent regulatory requirements and maintains product quality. The focus is on strengthening the regulatory and quality framework to support the successful commercialization of Vertex's therapies.

    Amy Longwell - Executive Assistant To Stephanie Franklin, SVP & Chief Human Resources Officer

    Amy Longwell, the Executive Assistant To Stephanie Franklin, SVP & Chief Human Resources Officer at Vertex, provides comprehensive administrative and strategic support to the Human Resources leadership. Managing complex schedules, coordinating key meetings, and facilitating communication, Longwell ensures the efficient operation of the HR department. This role involves handling sensitive information, organizing critical documentation, and supporting the execution of HR initiatives. By maintaining organizational flow and providing essential support, Amy Longwell enables the SVP & Chief Human Resources Officer to focus on strategic talent management and organizational development. The contribution is vital to fostering a productive and supportive work environment at Vertex.

    Robert Kauffman - Senior Vice President and Chief Marketing Officer

    Robert Kauffman, the Senior Vice President and Chief Marketing Officer at Vertex, shapes and executes the company's global marketing strategies. Directing all marketing initiatives, Kauffman ensures effective communication of Vertex's scientific advancements and therapeutic solutions to target audiences. This critical role involves overseeing brand management, market analysis, and promotional campaigns to drive market penetration and patient access. By developing compelling marketing narratives, Robert Kauffman enhances Vertex's brand visibility and supports the commercial success of its innovative medicines. The focus is on building strong market presence and communicating the value of Vertex's scientific contributions worldwide.

    Stephanie Franklin (she/her/hers) - Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals

    Stephanie Franklin, the Senior VP & Chief Human Resources Officer, Vertex Pharmaceuticals at Vertex, leads the company's human capital strategy and organizational development. Directing all HR functions, Franklin ensures Vertex attracts, develops, and retains top talent to support its mission of discovering transformative medicines. This leadership position involves overseeing talent acquisition, employee relations, compensation and benefits, and fostering a positive corporate culture. By implementing robust HR policies and programs, Stephanie Franklin cultivates a high-performing workforce and supports Vertex's long-term strategic goals. The focus is on building a world-class team and an environment where scientific innovation thrives.

    Explore Leadership Teams in Manufacturing

    Frequently Asked Questions Regarding Vertex Top Executives and Leadership Team

    Who leads Vertex?
    Vertex is led by Md Reshma Kewalramani (Chief Executive Officer & President), along with executives such as Christina Yi (Head Chief Operating Officer, Site (Seattle)) and Wayne Gombotz (Chief Technology Officer).
    Who is part of Vertex’s executive team?
    The executive team of Vertex includes leaders such as Md Reshma Kewalramani (Chief Executive Officer & President), Christina Yi (Head Chief Operating Officer, Site (Seattle)), Wayne Gombotz (Chief Technology Officer) and other senior executives.
    How many executives does Vertex have?
    Vertex has 10 executives leading key business areas.
    What roles are included in Vertex’s leadership team?
    The leadership team of Vertex includes roles such as Chief Executive Officer & President, Head Chief Operating Officer, Site (Seattle), Chief Technology Officer, Director, Chief of Staff, North America Commercial, Chief of Staff & Director.