Genentech Executive and Leadership Team

August, 2026

Leadership Overview

Genentech has 10 executives leading key functions including strategy, financial oversight, technology infrastructure, commercial marketing, and operational administration.

Committed to advancing life-saving biotechnology, Genentech prioritizes the development of innovative therapies for serious medical conditions through rigorous research and development to improve global patient outcomes.

Leadership Roles at Genentech

  • Chief Executive Officer - Ashley Magargee
  • Chief Financial Officer - Luke Liu
  • Chief Technology Officer - Roger Chylla
  • Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization - Alexa Hill
  • Director, Operations & Administration Chief of Staff - Jacquelin Harris
  • Pharma Technical Operations Hillsboro Chief of Staff - Afsaneh Sahavi
  • Senior Director, Chief of Staff, PD Regulatory - Jacqueline Jaszka
  • Senior Business Manager & Global To Head of Translational Medicine Omni Chief of Staff - Sneha Villivalam
  • Chief of Staff & Director, Operations & Administration, Solid Tumor Squad - Natasha Faville
  • Chief of Staff & Insights & Analytics Director, Commercial - Alexander Fischer
  • Ashley Magargee - Chief Executive Officer

    Ashley Magargee, the Chief Executive Officer at Genentech, directs the overarching strategic vision for the biotechnology enterprise. Magargee oversees the integration of research and development initiatives to ensure the delivery of innovative biopharmaceuticals. By aligning corporate objectives with long-term patient health goals, the Chief Executive Officer maintains a focus on sustainable growth within the competitive healthcare sector. Magargee manages high-level interactions with the Board to secure resources for clinical breakthroughs. This leadership role involves navigating complex regulatory landscapes while fostering a culture of scientific excellence. Through the optimization of internal processes, Ashley Magargee drives the company toward market leadership. Ultimately, the Chief Executive Officer ensures that the organization remains at the forefront of medical advancement, consistently delivering value to stakeholders and patients across diverse global markets.

    Luke Liu - Chief Financial Officer

    Luke Liu, the Chief Financial Officer at Genentech, manages the fiscal health and capital allocation strategies for the biotechnology firm. Liu oversees financial planning, reporting, and risk management to support the extensive research and development pipeline. By analyzing market trends and investment opportunities, the Chief Financial Officer ensures the company maintains a robust balance sheet capable of funding long-term clinical trials. Liu collaborates with executive leadership to prioritize resource distribution across various therapeutic areas. This role involves maintaining transparency with investors while driving operational efficiency to maximize shareholder value. Through rigorous financial oversight, Luke Liu secures the necessary capital to sustain the company's mission of developing life-saving therapies. Ultimately, the Chief Financial Officer provides the economic foundation required for the organization to scale its impact within the global healthcare industry.

    Roger Chylla - Chief Technology Officer

    Roger Chylla, the Chief Technology Officer at Genentech, architects the digital infrastructure and technological frameworks supporting advanced biopharmaceutical research. Chylla oversees the implementation of data-driven platforms that accelerate the discovery and development of innovative therapies. By integrating cutting-edge computational tools into the laboratory environment, the Chief Technology Officer enhances the precision and speed of clinical outcomes. Chylla manages cross-functional teams to ensure technological alignment with the company's broader scientific goals. This leadership role involves securing intellectual property through robust cybersecurity measures and optimizing data management systems for complex biological datasets. Through the deployment of scalable technology solutions, Roger Chylla drives operational excellence across the entire research organization. Ultimately, the Chief Technology Officer empowers scientists to translate complex data into actionable medical insights, reinforcing the company's position as a leader in biotechnology innovation.

    Alexa Hill - Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization

    Alexa Hill, the Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization at Genentech, directs the commercial strategy and market positioning for the company's therapeutic portfolio. Hill oversees the development of marketing campaigns that communicate the value of biopharmaceuticals to healthcare providers and patients. By analyzing market dynamics and competitive landscapes, the Chief Marketing Officer ensures that innovative therapies reach the populations requiring them most. Hill collaborates with commercial teams to align promotional activities with clinical evidence and regulatory requirements. This leadership role involves managing the administrative operations of the commercial organization to ensure seamless execution of product launches. Through strategic brand management, Alexa Hill drives market penetration and enhances the visibility of the company's medical solutions. Ultimately, the Chief Marketing Officer secures the commercial success necessary to continue the organization's commitment to improving patient outcomes.
    Alexa Hill

    Jacquelin Harris - Director, Operations & Administration Chief of Staff

    Jacquelin Harris, the Director, Operations & Administration Chief of Staff at Genentech, coordinates the daily operational activities and administrative functions of the executive office. Harris oversees the alignment of departmental workflows to ensure the efficient execution of corporate strategy. By facilitating communication between leadership teams, the Chief of Staff streamlines decision-making processes and enhances organizational agility. Harris manages complex projects that span multiple functional areas, ensuring that operational goals remain consistent with the company's mission. This role involves optimizing administrative resources to support the research and development teams in their pursuit of medical breakthroughs. Through the implementation of rigorous operational standards, Jacquelin Harris drives productivity and maintains organizational focus. Ultimately, the Director, Operations & Administration Chief of Staff provides the structural support necessary for the executive team to navigate the challenges of the biotechnology industry effectively.

    Afsaneh Sahavi - Pharma Technical Operations Hillsboro Chief of Staff

    Afsaneh Sahavi, the Pharma Technical Operations Hillsboro Chief of Staff at Genentech, manages the operational logistics and administrative coordination for the technical manufacturing facilities. Sahavi oversees the integration of production schedules with quality assurance protocols to ensure the consistent delivery of biopharmaceuticals. By facilitating collaboration between technical teams and executive leadership, the Chief of Staff ensures that manufacturing operations align with the company's broader supply chain strategy. Sahavi manages the administrative framework supporting the Hillsboro site, focusing on efficiency and regulatory compliance. This role involves identifying operational bottlenecks and implementing solutions to optimize production capacity. Through the coordination of technical resources, Afsaneh Sahavi drives the reliable manufacturing of life-saving therapies. Ultimately, the Pharma Technical Operations Hillsboro Chief of Staff ensures that the company's technical infrastructure remains capable of meeting the global demand for innovative medical treatments.

    Jacqueline Jaszka - Senior Director, Chief of Staff, PD Regulatory

    Jacqueline Jaszka, the Senior Director, Chief of Staff, PD Regulatory at Genentech, directs the administrative and operational strategy for the regulatory affairs department. Jaszka oversees the coordination of documentation and compliance efforts required for the approval of new biopharmaceuticals. By aligning regulatory timelines with research and development milestones, the Chief of Staff ensures that the company meets all legal and safety standards. Jaszka manages the flow of information between regulatory bodies and internal scientific teams to facilitate efficient product reviews. This role involves developing administrative processes that simplify complex regulatory submissions. Through the oversight of regulatory operations, Jacqueline Jaszka drives the timely advancement of the company's therapeutic pipeline. Ultimately, the Senior Director, Chief of Staff, PD Regulatory ensures that the organization maintains the highest standards of compliance while accelerating the delivery of innovative medical solutions to patients.

    Sneha Villivalam - Senior Business Manager & Global To Head of Translational Medicine Omni Chief of Staff

    Sneha Villivalam, the Senior Business Manager & Global To Head of Translational Medicine Omni Chief of Staff at Genentech, manages the business operations and strategic coordination for the translational medicine division. Villivalam oversees the integration of clinical research data into actionable business strategies that support the development of new therapies. By facilitating communication between global research teams, the Chief of Staff ensures that translational medicine initiatives align with the company's long-term scientific objectives. Villivalam manages the administrative and financial resources required to sustain high-impact research projects. This role involves optimizing the operational framework to accelerate the transition from laboratory discovery to clinical application. Through the coordination of global research efforts, Sneha Villivalam drives the efficiency of the translational medicine pipeline. Ultimately, the Senior Business Manager & Global To Head of Translational Medicine Omni Chief of Staff supports the organization's mission by ensuring that scientific innovation translates into tangible patient benefits.

    Natasha Faville - Chief of Staff & Director, Operations & Administration, Solid Tumor Squad

    Natasha Faville, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad at Genentech, directs the operational and administrative functions for the specialized oncology research unit. Faville oversees the coordination of clinical trials and research activities focused on solid tumor therapies. By aligning the squad's operational goals with the company's broader oncology strategy, the Chief of Staff ensures the efficient execution of research programs. Faville manages the administrative resources necessary to support the scientific team in their pursuit of cancer treatments. This role involves optimizing project workflows to accelerate the development of targeted therapies. Through the oversight of operations, Natasha Faville drives the productivity of the Solid Tumor Squad. Ultimately, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad ensures that the organization remains at the forefront of oncology research, delivering innovative solutions for patients facing serious medical conditions.

    Alexander Fischer - Chief of Staff & Insights & Analytics Director, Commercial

    Alexander Fischer, the Chief of Staff & Insights & Analytics Director, Commercial at Genentech, manages the data-driven strategy and administrative operations for the commercial division. Fischer oversees the collection and analysis of market insights to inform the company's commercial decision-making processes. By integrating advanced analytics into the commercial framework, the Chief of Staff ensures that marketing and sales strategies are based on robust evidence. Fischer coordinates the administrative functions of the commercial team to support the effective deployment of therapeutic products. This role involves identifying market opportunities and risks through detailed data evaluation. Through the application of analytical insights, Alexander Fischer drives the commercial success of the company's portfolio. Ultimately, the Chief of Staff & Insights & Analytics Director, Commercial provides the strategic intelligence necessary for the organization to maintain its competitive edge and continue delivering innovative therapies to the global healthcare market.

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    Frequently Asked Questions Regarding Genentech Top Executives and Leadership Team

    Who leads Genentech?
    Genentech is led by Ashley Magargee (Chief Executive Officer), along with executives such as Luke Liu (Chief Financial Officer) and Roger Chylla (Chief Technology Officer).
    Who is part of Genentech’s executive team?
    The executive team of Genentech includes leaders such as Ashley Magargee (Chief Executive Officer), Luke Liu (Chief Financial Officer), Roger Chylla (Chief Technology Officer) and other senior executives.
    How many executives does Genentech have?
    Genentech has 10 executives leading key business areas.
    What roles are included in Genentech’s leadership team?
    The leadership team of Genentech includes roles such as Chief Executive Officer, Chief Financial Officer, Chief Technology Officer, Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization, Director, Operations & Administration Chief of Staff.