Genentech Executive and Leadership Team

November, 2026

Leadership Overview

Genentech has 10 executives leading key functions including strategy, financial oversight, technological innovation, and operational administration.

Committed to advancing medical science, Genentech delivers transformative biopharmaceutical therapies to address serious health conditions while maintaining a rigorous focus on research-driven patient outcomes across global markets.

Leadership Roles at Genentech

  • Chief Executive Officer - Ashley Magargee
  • Chief Financial Officer - Luke Liu
  • Chief Financial Officer, Solid Tumor Squad - Matty Hackim
  • Chief Technology Officer - Roger Chylla
  • Chief of Staff & Director, Operations & Administration, Solid Tumor Squad - Natasha Faville
  • Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization - Alexa Hill
  • Pharma Technical Operations Hillsboro Chief of Staff - Afsaneh Sahavi
  • Director and Chief of Staff US Medical - Oncology Hematology - Beatriz Cansino
  • Chief of Staff & Insights & Analytics Director, Commercial - Alexander Fischer
  • Director, Operations & National Supply & Care Delivery Chief of Staff - Dwight Blass
  • Ashley Magargee - Chief Executive Officer

    Ashley Magargee, the Chief Executive Officer at Genentech, directs the overarching strategic vision for the development of innovative biopharmaceuticals. Magargee oversees the integration of research and development initiatives to ensure the delivery of therapies for serious medical conditions. By aligning corporate objectives with scientific breakthroughs, the Chief Executive Officer drives long-term growth and market competitiveness. This leadership role involves constant collaboration with the board to prioritize high-impact medical research. Ashley Magargee maintains a focus on operational excellence, ensuring that the organization remains at the forefront of the biotechnology sector. Through the management of complex organizational structures, the Chief Executive Officer fosters an environment of scientific discovery. Ultimately, Magargee secures the company's position as a leader in the healthcare industry by championing advancements that improve patient outcomes on a global scale.

    Luke Liu - Chief Financial Officer

    Luke Liu, the Chief Financial Officer at Genentech, manages the fiscal health and capital allocation strategies necessary for sustained biopharmaceutical innovation. Liu oversees financial planning, reporting, and risk management to support the company's extensive research and development pipeline. By optimizing resource distribution, the Chief Financial Officer ensures that capital investments align with the most promising therapeutic programs. This leadership role involves rigorous analysis of market trends to maintain financial stability while funding long-term scientific projects. Luke Liu directs the financial operations that underpin the company's ability to deliver life-saving treatments. Through the implementation of robust fiscal controls, the Chief Financial Officer supports the organization's mission to address serious medical conditions. Ultimately, Liu provides the economic foundation required for the company to continue its pursuit of groundbreaking medical solutions.

    Matty Hackim - Chief Financial Officer, Solid Tumor Squad

    Matty Hackim, the Chief Financial Officer, Solid Tumor Squad at Genentech, manages the financial planning and resource allocation specifically for the oncology division. Hackim oversees the budgeting and fiscal analysis required to support the development of therapies for solid tumors. By ensuring that financial resources are directed toward high-priority research projects, the Chief Financial Officer, Solid Tumor Squad drives the division's ability to innovate. This leadership role involves monitoring the financial performance of clinical trials and research initiatives. Matty Hackim directs the fiscal strategies that enable the Solid Tumor Squad to meet its development milestones. Through the implementation of precise financial controls, the Chief Financial Officer, Solid Tumor Squad supports the organization's mission to improve outcomes for cancer patients. Ultimately, Hackim ensures the financial viability of the division's efforts to bring new oncology treatments to market.

    Roger Chylla - Chief Technology Officer

    Roger Chylla, the Chief Technology Officer at Genentech, architects the digital and technical infrastructure required to accelerate biopharmaceutical research. Chylla oversees the implementation of advanced data analytics and computational tools that enhance the speed and accuracy of drug discovery. By integrating cutting-edge technology into laboratory workflows, the Chief Technology Officer drives efficiency across the research and development lifecycle. This leadership role involves managing complex technical systems that support the company's mission to improve patient outcomes. Roger Chylla directs the digital transformation efforts that enable the organization to process vast amounts of scientific data. Through the deployment of scalable technological solutions, the Chief Technology Officer ensures that the company remains competitive in the rapidly evolving biotechnology landscape. Ultimately, Chylla empowers scientific teams with the tools necessary to develop innovative therapies for serious medical conditions.

    Natasha Faville - Chief of Staff & Director, Operations & Administration, Solid Tumor Squad

    Natasha Faville, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad at Genentech, coordinates the operational activities and administrative functions for the oncology division. Faville oversees the alignment of internal processes to ensure that the Solid Tumor Squad functions with maximum efficiency. By streamlining communication and resource management, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad drives the execution of critical research projects. This leadership role involves facilitating cross-functional collaboration to support the development of therapies for complex cancers. Natasha Faville directs the administrative framework that allows scientific teams to focus on clinical breakthroughs. Through the optimization of operational workflows, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad ensures that the division meets its strategic goals. Ultimately, Faville supports the delivery of innovative oncology treatments to patients in need.

    Alexa Hill - Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization

    Alexa Hill, the Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization at Genentech, manages the administrative operations and strategic support for the commercial marketing leadership. Hill oversees the coordination of complex business activities that enable the effective promotion and distribution of biopharmaceutical products. By facilitating seamless communication between marketing teams and executive leadership, the Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization drives the successful implementation of commercial strategies. This leadership role involves organizing high-level initiatives that support the company's market presence. Alexa Hill directs the administrative processes that ensure marketing efforts align with the organization's broader mission. Through the management of operational priorities, the Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization ensures that commercial teams remain focused on delivering therapies to patients. Ultimately, Hill enhances the efficiency of the commercial portfolio organization.
    Alexa Hill

    Afsaneh Sahavi - Pharma Technical Operations Hillsboro Chief of Staff

    Afsaneh Sahavi, the Pharma Technical Operations Hillsboro Chief of Staff at Genentech, coordinates the operational and technical activities within the manufacturing and supply chain facilities. Sahavi oversees the alignment of production schedules and technical resources to ensure the consistent delivery of high-quality biopharmaceuticals. By facilitating communication across technical teams, the Pharma Technical Operations Hillsboro Chief of Staff drives the efficiency of the manufacturing process. This leadership role involves managing the operational complexities of large-scale production to support the company's therapeutic pipeline. Afsaneh Sahavi directs the administrative and operational initiatives that maintain the integrity of the supply chain. Through the optimization of technical workflows, the Pharma Technical Operations Hillsboro Chief of Staff ensures that manufacturing operations meet rigorous quality standards. Ultimately, Sahavi supports the company's ability to provide essential medications to patients through reliable and efficient technical operations.

    Beatriz Cansino - Director and Chief of Staff US Medical - Oncology Hematology

    Beatriz Cansino, the Director and Chief of Staff US Medical - Oncology Hematology at Genentech, manages the operational and strategic functions for the medical affairs division focused on oncology and hematology. Cansino oversees the coordination of medical research initiatives and clinical data dissemination to support the company's therapeutic portfolio. By streamlining internal processes, the Director and Chief of Staff US Medical - Oncology Hematology drives the effective communication of clinical evidence to healthcare providers. This leadership role involves facilitating collaboration between medical teams to ensure the successful development of oncology treatments. Beatriz Cansino directs the administrative framework that supports the medical affairs strategy. Through the optimization of operational workflows, the Director and Chief of Staff US Medical - Oncology Hematology ensures that the division achieves its clinical objectives. Ultimately, Cansino supports the advancement of medical knowledge and patient care in the oncology and hematology sectors.

    Alexander Fischer - Chief of Staff & Insights & Analytics Director, Commercial

    Alexander Fischer, the Chief of Staff & Insights & Analytics Director, Commercial at Genentech, manages the integration of data-driven insights into the company's commercial strategy. Fischer oversees the analytics teams responsible for interpreting market trends and patient needs to inform business decisions. By facilitating the use of advanced analytics, the Chief of Staff & Insights & Analytics Director, Commercial drives the development of effective commercial initiatives. This leadership role involves coordinating cross-functional efforts to ensure that data insights are translated into actionable business strategies. Alexander Fischer directs the analytical framework that supports the company's market presence. Through the optimization of data-driven processes, the Chief of Staff & Insights & Analytics Director, Commercial ensures that commercial teams are equipped with the information necessary to reach patients. Ultimately, Fischer enhances the company's ability to deliver therapies by leveraging deep market insights.

    Dwight Blass - Director, Operations & National Supply & Care Delivery Chief of Staff

    Dwight Blass, the Director, Operations & National Supply & Care Delivery Chief of Staff at Genentech, coordinates the operational logistics and supply chain management for the delivery of biopharmaceutical products. Blass oversees the processes that ensure the reliable distribution of therapies to healthcare providers and patients across the country. By streamlining supply chain operations, the Director, Operations & National Supply & Care Delivery Chief of Staff drives the efficiency of the care delivery network. This leadership role involves managing the complexities of national supply logistics to support the company's commitment to patient access. Dwight Blass directs the operational initiatives that maintain the integrity of the distribution system. Through the optimization of supply chain workflows, the Director, Operations & National Supply & Care Delivery Chief of Staff ensures that treatments reach those in need. Ultimately, Blass supports the company's mission by ensuring the seamless delivery of medical solutions.

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    Frequently Asked Questions Regarding Genentech Top Executives and Leadership Team

    Who leads Genentech?
    Genentech is led by Ashley Magargee (Chief Executive Officer), along with executives such as Luke Liu (Chief Financial Officer) and Matty Hackim (Chief Financial Officer, Solid Tumor Squad).
    Who is part of Genentech’s executive team?
    The executive team of Genentech includes leaders such as Ashley Magargee (Chief Executive Officer), Luke Liu (Chief Financial Officer), Matty Hackim (Chief Financial Officer, Solid Tumor Squad) and other senior executives.
    How many executives does Genentech have?
    Genentech has 10 executives leading key business areas.
    What roles are included in Genentech’s leadership team?
    The leadership team of Genentech includes roles such as Chief Executive Officer, Chief Financial Officer, Chief Financial Officer, Solid Tumor Squad, Chief Technology Officer, Chief of Staff & Director, Operations & Administration, Solid Tumor Squad.