Genentech Executive and Leadership Team

July, 2026

Leadership Overview

Genentech has 10 executives leading key functions including strategy, marketing, technology, and operations.

Driven by a commitment to scientific advancement, Genentech focuses on pioneering biopharmaceuticals to address serious medical conditions and enhance patient outcomes through rigorous research and development.

Leadership Roles at Genentech

  • Chief Executive Officer - Ashley Magargee
  • Chief Marketing Officer - Zoë Lazarre
  • Chief of Staff - Cynthia Shafer
  • Chief Technology Officer - Roger Chylla
  • Chief of Staff & Director, Operations & Administration, Solid Tumor Squad - Natasha Faville
  • Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization - Alexa Hill
  • Strategy Lead & , Early Cancer Chief of Staff - Stefan Goshev
  • Director, Operations & National Supply & Care Delivery Chief of Staff - Dwight Blass
  • Chief of Staff & Insights & Analytics Director, Commercial - Alexander Fischer
  • Senior To The Communications Leader & Chief Medical Officer & Chief Marketing Officer - Arianna Ames
  • Ashley Magargee - Chief Executive Officer

    Ashley Magargee, the Chief Executive Officer at Genentech, directs the company's overall strategic vision and operational execution. Magargee guides the organization's focus on developing groundbreaking therapies for severe medical conditions, aligning all departments with the core mission of improving patient lives. This leadership role involves fostering a culture of innovation and scientific excellence, ensuring Genentech remains at the forefront of biopharmaceutical research and development. Ashley Magargee oversees the integration of scientific discovery with market needs, driving the company's growth and impact within the healthcare sector. The Chief Executive Officer's purview extends to key partnerships and resource allocation, solidifying Genentech's position as a leader in biotechnology.

    Zoë Lazarre - Chief Marketing Officer

    Zoë Lazarre, the Chief Marketing Officer at Genentech, architects the company's comprehensive marketing and commercial strategies. Lazarre drives the go-to-market approach for Genentech's innovative therapies, ensuring effective communication of their value to healthcare providers and patients. This involves overseeing market analysis, brand development, and promotional campaigns that highlight the company's commitment to improving patient outcomes in serious medical conditions. The Chief Marketing Officer collaborates closely with research and development teams to translate scientific advancements into compelling market narratives. Zoë Lazarre's leadership ensures that Genentech's biopharmaceutical solutions reach those who need them most, maximizing the company's positive impact on global health.
    Zoë Lazarre

    Cynthia Shafer - Chief of Staff

    Cynthia Shafer, the Chief of Staff at Genentech, provides critical operational and strategic support to executive leadership. Shafer streamlines internal processes and enhances organizational efficiency, ensuring seamless execution of company initiatives. This role involves managing key projects, facilitating cross-functional communication, and driving strategic alignment across various departments focused on biopharmaceutical development. The Chief of Staff acts as a key liaison, connecting different teams to advance Genentech's mission of creating innovative therapies for serious medical conditions. Cynthia Shafer's contributions are vital to maintaining operational excellence and supporting the company's research and development objectives.

    Roger Chylla - Chief Technology Officer

    Roger Chylla, the Chief Technology Officer at Genentech, spearheads the company's technological infrastructure and digital transformation efforts. Chylla directs the implementation of advanced technologies that support Genentech's cutting-edge research and development in biopharmaceuticals. This leadership position involves overseeing data management, computational biology, and the technological systems essential for discovering and developing innovative therapies for serious medical conditions. The Chief Technology Officer ensures that Genentech leverages state-of-the-art tools to accelerate scientific breakthroughs and improve patient outcomes. Roger Chylla's expertise is fundamental to maintaining the company's technological advantage and driving operational efficiency in its pursuit of medical advancements.

    Natasha Faville - Chief of Staff & Director, Operations & Administration, Solid Tumor Squad

    Natasha Faville, the Chief of Staff & Director, Operations & Administration, Solid Tumor Squad at Genentech, manages critical operational functions and administrative support for the Solid Tumor Squad. Faville ensures the efficient execution of projects and initiatives within this specialized research group, focusing on developing novel therapies for solid tumors. This dual role involves overseeing administrative processes and driving operational excellence to support the squad's groundbreaking work in biopharmaceuticals. The Chief of Staff & Director, Operations & Administration, Solid Tumor Squad facilitates collaboration and resource allocation, directly contributing to Genentech's mission of improving patient outcomes for serious medical conditions. Natasha Faville's leadership enhances the productivity and strategic focus of the Solid Tumor Squad.

    Alexa Hill - Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization

    Alexa Hill, the Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization at Genentech, provides essential administrative and operational support to the Chief Marketing Officer and the Commercial Portfolio Organization. Hill ensures the smooth functioning of daily operations, manages key communications, and facilitates project coordination within the marketing division. This role is crucial for aligning marketing strategies with Genentech's broader objectives of developing and delivering innovative therapies for serious medical conditions. The Principal Administrative Business Partner, Chief Marketing Officer. Commercial Portfolio Organization plays a key part in optimizing workflow and supporting the commercialization efforts of Genentech's biopharmaceutical products, ultimately contributing to improved patient outcomes.

    Stefan Goshev - Strategy Lead & , Early Cancer Chief of Staff

    Stefan Goshev, the Strategy Lead & Early Cancer Chief of Staff at Genentech, drives strategic planning and operational coordination for early cancer research initiatives. Goshev develops and implements strategic frameworks that guide the discovery and development of novel therapies for early-stage cancer. This leadership position involves fostering collaboration among research teams and ensuring alignment with Genentech's overarching mission to combat serious medical conditions. The Strategy Lead & Early Cancer Chief of Staff plays a pivotal role in translating scientific insights into actionable strategies, accelerating the path from research to patient benefit. Stefan Goshev's focus on early-stage innovation is critical to expanding Genentech's pipeline of life-changing biopharmaceuticals.

    Dwight Blass - Director, Operations & National Supply & Care Delivery Chief of Staff

    Dwight Blass, the Director, Operations & National Supply & Care Delivery Chief of Staff at Genentech, oversees critical operational aspects of national supply chains and care delivery systems. Blass ensures the efficient and reliable distribution of Genentech's biopharmaceutical products, supporting patient access to innovative therapies for serious medical conditions. This role involves optimizing logistics, managing supply chain complexities, and enhancing care delivery processes to meet patient needs effectively. The Director, Operations & National Supply & Care Delivery Chief of Staff collaborates with various stakeholders to ensure seamless operations from manufacturing to patient administration. Dwight Blass's leadership is instrumental in maintaining the integrity and effectiveness of Genentech's operational network, directly impacting patient outcomes.

    Alexander Fischer - Chief of Staff & Insights & Analytics Director, Commercial

    Alexander Fischer, the Chief of Staff & Insights & Analytics Director, Commercial at Genentech, leads the integration of data analytics into commercial strategy and operations. Fischer drives the generation of actionable insights from market data to inform decision-making across the commercial portfolio. This role is crucial for understanding market dynamics and optimizing the go-to-market strategies for Genentech's innovative therapies, particularly in addressing serious medical conditions. The Chief of Staff & Insights & Analytics Director, Commercial ensures that data-driven approaches enhance the effectiveness of marketing and sales efforts. Alexander Fischer's expertise in analytics is vital for maximizing the impact of Genentech's biopharmaceutical solutions and improving patient access.

    Arianna Ames - Senior To The Communications Leader & Chief Medical Officer & Chief Marketing Officer

    Arianna Ames, the Senior To The Communications Leader & Chief Medical Officer & Chief Marketing Officer at Genentech, provides strategic leadership across communications, medical affairs, and marketing functions. Ames ensures cohesive messaging and strategic alignment for Genentech's scientific and commercial endeavors, particularly concerning innovative therapies for serious medical conditions. This multifaceted role involves translating complex medical information into accessible communications and guiding marketing strategies that resonate with healthcare professionals and patients. The Senior To The Communications Leader & Chief Medical Officer & Chief Marketing Officer plays a key part in shaping Genentech's public perception and market presence. Arianna Ames's integrated leadership strengthens the company's ability to convey the value of its biopharmaceutical advancements and improve patient outcomes.

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    Frequently Asked Questions Regarding Genentech Top Executives and Leadership Team

    Who leads Genentech?
    Genentech is led by Ashley Magargee (Chief Executive Officer), along with executives such as Zoë Lazarre (Chief Marketing Officer) and Cynthia Shafer (Chief of Staff).
    Who is part of Genentech’s executive team?
    The executive team of Genentech includes leaders such as Ashley Magargee (Chief Executive Officer), Zoë Lazarre (Chief Marketing Officer), Cynthia Shafer (Chief of Staff) and other senior executives.
    How many executives does Genentech have?
    Genentech has 10 executives leading key business areas.
    What roles are included in Genentech’s leadership team?
    The leadership team of Genentech includes roles such as Chief Executive Officer, Chief Marketing Officer, Chief of Staff, Chief Technology Officer, Chief of Staff & Director, Operations & Administration, Solid Tumor Squad.