Caris Life Sciences Executive and Leadership Team

September, 2026

Leadership Overview

Caris Life Sciences has 4 executives leading key functions including financial strategy, technological innovation, organizational management, and operational excellence.

Driven by a commitment to precision medicine, Caris Life Sciences transforms patient care through data-informed insights. This organization empowers physicians with high-quality disease information to improve global health outcomes.

Leadership Roles at Caris Life Sciences

  • Executive Vice President & Chief of Staff & Chief Executive Officer, Office of - Stephanie Thomas
  • Chief Financial Officer - Luke Power
  • Senior Vice President and Chief Technology Officer - Valeriy Domenyuk
  • Chief Operations Officer - Jon Harmon
  • Stephanie Thomas - Executive Vice President & Chief of Staff & Chief Executive Officer, Office of

    Stephanie Thomas, the Executive Vice President & Chief of Staff & Chief Executive Officer, Office of at Caris Life Sciences, coordinates strategic initiatives across all internal departments. Overseeing the executive office, the Executive Vice President & Chief of Staff & Chief Executive Officer, Office of ensures that corporate objectives remain synchronized with the overarching mission of precision medicine. This leadership role involves managing high-priority projects and facilitating communication between the C-suite and the broader organization. By streamlining internal processes, Stephanie Thomas enhances the efficiency of the company. Thomas manages the execution of long-term goals, ensuring that every functional area contributes to the goal of improving patient outcomes. Through the management of the executive office, the Executive Vice President & Chief of Staff & Chief Executive Officer, Office of drives organizational alignment, fostering a culture of excellence that supports the rapid deployment of diagnostic services across diverse medical markets.

    Luke Power - Chief Financial Officer

    Luke Power, the Chief Financial Officer at Caris Life Sciences, directs all fiscal planning and capital allocation strategies. Overseeing the financial health of the organization, the Chief Financial Officer ensures alignment between budgetary resources and the research-heavy requirements of precision medicine. This leadership role involves managing investor relations and securing the capital necessary for scaling transformative diagnostic technologies across North American markets. By optimizing the cost structure of laboratory operations, Luke Power directly impacts the long-term sustainability of the company. Power maintains rigorous oversight of financial reporting, ensuring transparency for the Board while supporting the rapid expansion of data-driven service lines. Through disciplined fiscal management, the Chief Financial Officer secures the resources required to advance the mission of improving patient lives through superior disease information and cutting-edge molecular profiling services.
    Luke Power

    Valeriy Domenyuk - Senior Vice President and Chief Technology Officer

    Valeriy Domenyuk, the Senior Vice President and Chief Technology Officer at Caris Life Sciences, architects the computational infrastructure required for massive-scale genomic data analysis. Overseeing the development of proprietary algorithms, the Senior Vice President and Chief Technology Officer drives the integration of artificial intelligence into clinical diagnostic workflows. This leadership role involves bridging the gap between complex biological data and actionable medical insights for physicians globally. By refining the technological stack, Valeriy Domenyuk accelerates the delivery of precision medicine solutions. Domenyuk collaborates with research teams to ensure the platform remains at the forefront of molecular science. Through the continuous evolution of data processing capabilities, the Senior Vice President and Chief Technology Officer maintains the competitive advantage of the company in the rapidly changing landscape of biotechnology, ensuring that every patient receives the most accurate disease information available today.

    Jon Harmon - Chief Operations Officer

    Jon Harmon, the Chief Operations Officer at Caris Life Sciences, manages the end-to-end logistics of laboratory testing and service delivery. Overseeing the daily operations of the company, the Chief Operations Officer ensures that high-quality disease information reaches physicians with maximum speed and accuracy. This leadership role involves optimizing supply chain efficiency and scaling laboratory capacity to meet the growing demand for molecular profiling. By refining operational workflows, Jon Harmon supports the company's commitment to precision medicine. Harmon coordinates with technical teams to maintain the highest standards of quality control across all testing facilities. Through the implementation of lean methodologies, the Chief Operations Officer drives productivity gains, ensuring that the organization remains agile while scaling operations to serve a broader patient population. Harmon secures the operational foundation necessary for the company to continue trailblazing the path to personalized healthcare solutions.

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    Frequently Asked Questions Regarding Caris Life Sciences Top Executives and Leadership Team

    Who leads Caris Life Sciences?
    Caris Life Sciences is led by Stephanie Thomas (Executive Vice President & Chief of Staff & Chief Executive Officer, Office of), along with executives such as Luke Power (Chief Financial Officer) and Valeriy Domenyuk (Senior Vice President and Chief Technology Officer).
    Who is part of Caris Life Sciences’s executive team?
    The executive team of Caris Life Sciences includes leaders such as Stephanie Thomas (Executive Vice President & Chief of Staff & Chief Executive Officer, Office of), Luke Power (Chief Financial Officer), Valeriy Domenyuk (Senior Vice President and Chief Technology Officer) and other senior executives.
    How many executives does Caris Life Sciences have?
    Caris Life Sciences has 4 executives leading key business areas.
    What roles are included in Caris Life Sciences’s leadership team?
    The leadership team of Caris Life Sciences includes roles such as Executive Vice President & Chief of Staff & Chief Executive Officer, Office of, Chief Financial Officer, Senior Vice President and Chief Technology Officer, Chief Operations Officer.