Spruce Biosciences
Manufacturing · California, United States · 1-10 Employees
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Overview
Headquarters
611 Gateway Blvd Ste 740, South San Fran...Phone Number
(415) 655-4168Website
www.sprucebio.comRevenue
-Stock Symbol
SPRBIndustry
ZI Rank: 1
Signal Type
Feb
Mar
Apr
May
Jun
Jul
ZI Rank
2
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About Spruce Biosciences
Spruce Biosciences is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical needs. The company is developing its wholly-owned product candidate, tildacerfont, as a potential first non-steroidal therapy for patients with classic congenital adrenal hyperplasia (CAH), a serious and life-threatening disease with no novel therapies approved for decades. Spruce is also advancing tildacerfont for women affected by a rare form of polycystic ovary syndrome (PCOS) characterized by primary adrenal androgen excess.Explore more
Spruce Biosciences Org Chart
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Vice President, Clinical Development
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Company Profile Activity
Activity Insights
Spruce Biosciences is experiencing very low activity levels compared to other companies in the Business Services sector.
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Spruce Biosciences is drawing exceptional interest within the Business Services industry, suggesting notable developments or strong market momentum, learn more about Spruce Biosciences.
Spruce Biosciences financials insights
Gather financial insights about Spruce Biosciences, including details on funding rounds, investors, total funding, and acquisitions, to gain a comprehensive understanding of their financial strategy.
2017
Series A
$20M
2020
Series B
$88M
Stock Offering
$90M
2023
Share Placement
$53.6M
2025
Stock/Share Issuance
$50M
Stock/Share Issuance
$50M
2026
Debt
$50M
Unspecified
$5.5M
Spruce Biosciences Tech Stack
A closer look at the technologies used by Spruce Biosciences
Most Recent Scoops
Project
Spruce Bio has a monoclonal antibody in its pipeline targeting congenital adrenal hyperplasia (CAH), which binds CRH as a ligand a mechanism validated by the prior FDA approval of crinecerfont (by Neurocrine) for the same indication.
Medical Research, Pharmaceuticals
Project
Spruce Bio has reported that its five-year biomarker data profound heparan sulfate levels in the CSF within the limit of normal at most time points a result not previously achieved by any other therapeutic or ERT for neuropathic MPS.
Medical Research, Pharmaceuticals
Project
Spruce Bio is planning to initiate an expanded access program in the second half of 2026, in partnership with patient foundations, to allow patients to transition from its clinical trial to commercial product upon availability.
Partnership, Product Launch, Clinical Operations
Project
Spruce Bio has reported that Tralesinidase alfa demonstrates systemic efficacy through normalization of liver and spleen sizes, and a favorable safety profile with no meaningful hypersensitivity reactions and no reduction in therapeutic effect size even in patients where neutralizing antibodies were detected.
Medical Research, Pharmaceuticals
Project
Spruce Biosciences News & Media
Spruce Biosciences (NASDAQ: SPRB) names Adrian Quartel as chief medical officer
Adrian Quartel, M.D., FFPM joins Spruce Biosciences as CMO, bringing 25+ years of pharma experience and leadership in launching six rare disease treatments at BioMarin.Spruce Biosciences (SPRB) Appoints Dale Hooks as CCO and Reports Narrowed $39M 2025 Net Loss
Spruce Biosciences Inc. (NASDAQ:SPRB) is one of the best hot stocks to buy according to analysts. On March 9, Spruce Biosciences appointed Dale Hooks as Chief Commercial Officer to lead the company’s transition toward its next phase of growth. Hooks brings nearly 35 years of biopharmaceutical experience to the role, having overseen 21 new product […]Spruce Biosciences Touts MPS IIIB Data, Targets Q4 BLA Submission at Oppenheimer Conference
Executives from Spruce Biosciences (NASDAQ:SPRB) outlined regulatory plans, clinical data highlights, and commercial considerations for the company’s lead program in Sanfilippo syndrome type B (MPS IIIB) during a fireside chat at Oppenheimer’s 36th Annual Healthcare and Life Sciences Conference. PrHarbour BioMed stake in US drug firm Spruce shows Chinese firms' growing clout, analysts say
Latest example of Chinese drug maker acquiring equity in overseas partner shows they are becoming true development partners, analysts say.
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Frequently Asked Questions Regarding Spruce Biosciences
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Spruce Biosciences is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical needs. The company is developing its wholly-owned product candidate, tildacerfont, as a potential first non-steroidal therapy for patients with classic congenital adrenal... Read More
