Spruce Bio
Business Services · California, United States · 1-10 Employees
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Overview
Headquarters
611 Gateway Blvd Ste 740, South San Fran...Phone Number
(415) 343-5986Website
www.sprucebio.comRevenue
-Stock Symbol
SPRBIndustry
ZI Rank: 1
Signal Type
Jan
Feb
Mar
Apr
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Jun
ZI Rank
3
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About Spruce Bio
Spruce Biosciences is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical needs. The company is developing its wholly-owned product candidate, tildacerfont, as a potential first non-steroidal therapy for patients with classic congenital adrenal hyperplasia (CAH), a serious and life-threatening disease with no novel therapies approved for decades. Spruce is also advancing tildacerfont for women affected by a rare form of polycystic ovary syndrome (PCOS) characterized by primary adrenal androgen excess.Explore more
Spruce Bio Org Chart
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Vice President, Clinical Development
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Company Profile Activity
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Spruce Bio is experiencing very low activity levels compared to other companies in the Manufacturing sector.
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Spruce Bio is drawing exceptional interest within the Manufacturing industry, suggesting notable developments or strong market momentum, learn more about Spruce Bio.
Spruce Bio financials insights
Gather financial insights about Spruce Bio, including details on funding rounds, investors, total funding, and acquisitions, to gain a comprehensive understanding of their financial strategy.
2017
Series A
$20M
2020
Series B
$88M
Stock Offering
$90M
2023
Share Placement
$53.6M
2025
Stock/Share Issuance
$50M
Private Equity
$50M
2026
Debt
$50M
Spruce Bio Tech Stack
A closer look at the technologies used by Spruce Bio
Most Recent Scoops
Project
Spruce Bio has a monoclonal antibody in its pipeline targeting congenital adrenal hyperplasia (CAH), which binds CRH as a ligand a mechanism validated by the prior FDA approval of crinecerfont (by Neurocrine) for the same indication.
Medical Research, Pharmaceuticals
Project
Spruce Bio has reported that its five-year biomarker data profound heparan sulfate levels in the CSF within the limit of normal at most time points a result not previously achieved by any other therapeutic or ERT for neuropathic MPS.
Medical Research, Pharmaceuticals
Project
Spruce Bio is planning to initiate an expanded access program in the second half of 2026, in partnership with patient foundations, to allow patients to transition from its clinical trial to commercial product upon availability.
Partnership, Product Launch, Clinical Operations
Project
Spruce Bio has reported that Tralesinidase alfa demonstrates systemic efficacy through normalization of liver and spleen sizes, and a favorable safety profile with no meaningful hypersensitivity reactions and no reduction in therapeutic effect size even in patients where neutralizing antibodies were detected.
Medical Research, Pharmaceuticals
Project
Spruce Bio News & Media
Spruce Biosciences Touts MPS IIIB Data, Targets Q4 BLA Submission at Oppenheimer Conference
Executives from Spruce Biosciences (NASDAQ:SPRB) outlined regulatory plans, clinical data highlights, and commercial considerations for the company’s lead program in Sanfilippo syndrome type B (MPS IIIB) during a fireside chat at Oppenheimer’s 36th Annual Healthcare and Life Sciences Conference. PrHarbour BioMed stake in US drug firm Spruce shows Chinese firms' growing clout, analysts say
Latest example of Chinese drug maker acquiring equity in overseas partner shows they are becoming true development partners, analysts say.Harbour BioMed takes 3.8% stake in Spruce Biosciences | SPRB Stock News
Warrant exercise gives Harbour BioMed 3.8% of Spruce’s shares and 3.1% on a fully diluted basis, tightening their SPR202 antibody pact for adrenal disorders.Harbour BioMed Exercises Warrant To Acquire Stake In Spruce Biosciences - RTTNews
Harbour BioMed announced that, through its wholly-owned subsidiary, it has exercised its warrant to acquire common stock in Spruce Biosciences Inc. (SPRB). As a result of this transaction, Harbour BioMed now holds approximately 3.
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Spruce Biosciences is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical needs. The company is developing its wholly-owned product candidate, tildacerfont, as a potential first non-steroidal therapy for patients with classic congenital adrenal... Read More
