Shanghai Center for Bioinformation Technology

SCBIT is composed of 14 departments:Administration Office, Biomedical Informatics Research Group, Functional Genomics Research Group, Systems Biology Research Group, Translational Medicine Research Group, Pathogen Genomics Research Group, Evolutionary Biology Research Group, Computational Chemical Biology Research Group, Bioinformatics Application... Software R&D, Technology Support, Life Science Data Center, Software Department and Deep Sequencing Data Analysis Department. The development of biomedical informatics system, laboratory information management system, life science data center and omicsinformation analysis system has made great progress. Some marketed products has been framework developed, other has been semifinished products and other has been ready to be promoted. Our life science data center has built Schistosoma japonicum database, medical microbiology database, HotData database, Brain Protein database, paralogous protein database, Arabidopsis thaliana protein-protein interaction database, disease-related protein mutation information database, human body fluid information database, Experimental and patented gene database, Post-translational modification Protein database, zinc finger protein database and Protein dynamic network information database. Also several data analytical systems or platforms have been developed, including Small Molecule Functional Alignment System, Gene interaction network prediction system, Chinese Medicine components and protein interaction prediction and analysis system, Microarray Data Quality Management System, Conserved Sequence fragment chromosome localization and analysis system, Transcription Factor prediction and recognition system. Most of these systems have been put into public services and we developed a novel method for dynamical study of protein-protein interaction and network construction. Furthermore, achievements over the past years will be gradually integrated into the "OmicsExplore" system of significant National 863 Program which is carried by Center. ...Read More