One Brave Idea

If all goes as hoped, One Brave Idea will produce a way to detect coronary disease decades before symptoms arise. That would unlock a world of opportunities - insights into mechanisms, new treatments and therapies that could prevent patients from making the leap from disease-carrier to disease-sufferer. In parallel, MacRae and his team, with the ad... vice of the venture capitalist, will seek more funding so scientists can continue down the most promising paths toward a cure for coronary heart disease. The other objective of One Brave Idea is upending the ways in which medical research is funded and organized. If MacRae's method works, One Brave Idea could become the new paradigm for studying many diseases. "Traditional biomedical research has done a lot for us, but can only do so much more," MacRae said. "Instead of continuing to seek an incremental biological approach, we're being eclectic. It's almost like crowdsourcing in many different crowds. It's time to begin using the remarkable advances in all of society to try a more holistic approach to solving our disease problems."Read More