NIMML Institute

The NIMML Institute is a 501 (c) (3) non-profit public charity foundation focused on a transdisciplinary, team-science approach to precision medicine at the interface of immunology, inflammation, and metabolism. The NIMML Institute team has led numerous large-scale transdisciplinary projects and is dedicated to solving important societal problems b... y combining the expertise of immunologists, computational biologists, toxicologists, modelers, translational researchers, and molecular biologists. The central integrative theme of NIMML Institute is the view of the immune system as a massively and dynamically interacting system and the application of novel advanced computational methods to unravel its complexity and accelerate the discovery and characterization of novel pathways to enable the development of new classes of therapeutics for autoimmune, infectious, and chronic inflammatory diseases. NIMML was founded in 2002 under the guidance of Dr. Bassaganya-Riera and Dr. Hontecillas. The NIMML Institute is committed to transdisciplinary, team-science approaches with a personalized medicine focus at the interface of immunology, inflammation, and metabolism. The NIMML research programs incorporate drug development, nutritional immunology, immunometabolism, computational immunology, and clinical and translational research in autoimmune, infectious, and chronic inflammatory diseases. The scope of NIMMLs research ranges from in silico and in vitro studies to mechanistic, translational and Phase 1-4 clinical trials. The NIMML research has pioneered platforms applying high-throughput computational, experimental immunology techniques, and system biology approaches in translational immunology research and discovery. Through the NIAID-funded Center for Modeling Immunity to Enteric Pathogens under the Modeling Immunity for Biodefense (MIB) program, the NIMML applied advanced computational approaches to analyze high-dimensional, high-throughput datasets, model and simulate human immunology systems and help immunologists ...Read More