NanoSight

NanoSight's "Nanoparticle Tracking Analysis" NTA detects and visualizes populations of nanoparticles in liquids down to 10 nm, dependent on the material, and measures the size of each particle from direct observations of diffusion. Additionally, NanoSight measures concentration and a fluorescence mode differentiates suitably-labelled particles with... in complex background suspensions. Zeta potential measurements are similarly particle specific. This particle-by-particle methodology provides high-resolution particle size distributions and validates data with information-rich video files of the particles moving under Brownian motion. This simultaneous multi-parameter characterization matches the demands of complex biological systems, hence its wide application in the development of drug delivery systems, of viral vaccines, and in nanotoxicology. This real-time data give insight into the kinetics of protein aggregation and other time-dependent phenomena in a qualitative and quantitative manner. NanoSight has a growing role in biodiagnostics, being proven in the detection and speciation of nanovesicles (exosomes) and microvesicles. NanoSight has more than 600 systems worldwide with users including BASF, GlaxoSmithKline, Merck, Novartis, Pfizer, Proctor and Gamble, Roche and Unilever, together with eminent universities and research institutes. NanoSight's technology is validated by 900+ third party papers citing NanoSight results. The company's position in nanoparticle characterization is consolidated further with publication of an ASTM International Standard, ASTM E2834, which describes the NTA methodology for detection and analysis of nanoparticles.Read More