MetaVia
Manufacturing · Massachusetts, United States · 1-10 Employees
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Overview
Headquarters
545 Concord Ave Ste 210, Cambridge, Mass...Phone Number
(857) 702-9600Website
www.metaviatx.comRevenue
-Stock Symbol
MTVAIndustry
ZI Rank: 1
Signal Type
Feb
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ZI Rank
1
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About MetaVia
MetaVia formerly known as NeuroBo Pharmaceuticals is a clinical-stage biotechnology company focused on transforming cardiometabolic diseases. The company is currently developing DA-1726 for the treatment of obesity and DA-1241 for the treatment of Metabolic Dysfunction-Associated Steatohepatitis (MASH).Explore more
MetaVia Org Chart
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Most Recent Scoops
Person-Based
Events, Finance, Investor Relations
Project
MetaVia has observed a reduction of nearly 10 cm in waist circumference over eight weeks in the DA1726 48 mg cohort, believed to reflect visceral fat reduction, with full-body MRI being conducted in the current phase to confirm the source of this reduction. For context, Boehringer Ingelheim's surbuditide phase three data over more than 18 months showed 34% visceral fat reduction, and no comparable visceral fat reduction data has been reported for semaglutide or other GLP-1 agents.
Project
MetaVia has conducted non-clinical combination studies of vanoclopramide with resmetirom, achieving approximately 22% weight loss in mice without a change in food intake versus monotherapy arms, suggesting a mechanism distinct from GLP-1-driven appetite suppression that may be relevant for GLP-1 non-responders or intolerant patients. A separate combination with metformin showed improved glycemic control and modest additional weight loss versus metformin alone.
Medical Research
Project
MetaVia has planned an FDA meeting in the second half of this year to discuss the development strategy for a vanoclopramide and resmetirom combination program, including whether biopsy requirements can be avoided and whether a direct phase three entry is feasible, leveraging resmetirom's existing biopsy dataset as an approved drug.
Medical Research, Pharmaceuticals, Clinical Operations
Project
Medical Research, Pharmaceuticals, Clinical Operations
MetaVia News & Media
MetaVia Announces Completion of Dose Titration in Phase 1 Part 3 Study of DA-1726 for the Treatment of Obesity
All Active Patients in Both Cohorts Have Successfully Reached Highest Target Doses of 48 mg and 64 mg Topline Data Remains on Track for Fourth Quarter 2026 CAMBRIDGE, Mass., July 9, 2026 /PRNewswire/ -- MetaVia Inc. (Nasdaq: MTVA), a clinical-stage biotechnology company focused on...MetaVia Presents New Late-Breaking Obesity and Metabolic Data at the ADA 2026 Scientific Sessions Supporting DA-1726 Differentiation and Vanoglipel Combination Potential
DA-1726 Phase 1, 48 mg Cohort Achieved Up to 9.1% Mean Body Weight Reduction at Day 54 Without Evidence of Plateau Vanoglipel Combined with Resmetirom Demonstrated Synergistic Hepatoprotective and Weight-Loss Effects in Preclinical MASH Model Vanoglipel Combined with Metformin...MetaVia to Highlight Novel Obesity and Metabolic Therapies at Upcoming Emerging Growth Conference
CAMBRIDGE, Mass., June 4, 2026 /PRNewswire/ -- MetaVia Inc. (Nasdaq: MTVA), a clinical-stage biotechnology company focused on transforming cardiometabolic diseases, today announced that Hyung Heon Kim, President and Chief Executive Officer and Marshall H. Woodworth, Chief Financial...MetaVia Presents Higher-Dose Phase 1 Results for DA-1726 at EASL Congress 2026, Supporting Potential in Obesity and MASH
48 mg Cohort Achieved Up to 9.1% Mean Body Weight Reduction at Day 54 Without Evidence of Plateau Exploratory FibroScan Assessments Demonstrated Early Liver-Related Improvements Ongoing Phase 1 Part 3a/3b Titration Studies Continue to Evaluate Extended Treatment at Higher-Dose Levels...
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MetaVia formerly known as NeuroBo Pharmaceuticals is a clinical-stage biotechnology company focused on transforming cardiometabolic diseases. The company is currently developing DA-1726 for the treatment of obesity and DA-1241 for the treatment of Metabolic Dysfunction-Associated Steatohepatitis (MASH).... Read More
