MapLight Therapeutics
Highly Engaged Employees
Highly Engaged EmployeesManufacturing · California, United States · 51-200 Employees
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Overview
Headquarters
800 Chesapeake Dr, Redwood City, Califor...Phone Number
(617) 984-6300Website
www.maplightrx.comRevenue
-Industry
ZI Rank: 1
Signal Type
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ZI Rank
1
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About MapLight Therapeutics
MapLight Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system disorders. The company was founded by globally recognized leaders in psychiatry and neuroscience research to address the lack of circuit-specific pharmacotherapies available for patients. MapLights discovery platform holds the potential to fill this void by identifying neural circuits causally linked to disease and targeting those circuits for therapeutic modulation.Explore more
MapLight Therapeutics Org Chart
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Revenue
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Founded In
Company Profile Activity
Activity Insights
MapLight Therapeutics is experiencing very low activity levels compared to other companies in the Manufacturing sector.
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MapLight Therapeutics is drawing exceptional interest within the Manufacturing industry, suggesting notable developments or strong market momentum, learn more about MapLight Therapeutics.
MapLight Therapeutics financials insights
Gather financial insights about MapLight Therapeutics, including details on funding rounds, investors, total funding, and acquisitions, to gain a comprehensive understanding of their financial strategy.
2023
Series C
$225M
2025
Multiple Rounds
$819.6M
MapLight Therapeutics Tech Stack
A closer look at the technologies used by MapLight Therapeutics
Most Recent Scoops
Project
Laboratory Operations, Medical Research, Clinical Operations
Project
MapLight Therapeutics has announced plans to request an end-of-phase 2 meeting with the FDA following a full data review of the IRIS trial, with the regulatory pathway for irritability in autism spectrum disorder already established through prior approvals of aripiprazole and Risperdal using the ABC-I scale as the primary endpoint the same scale used in IRIS.
Clinical Operations
Project
reported three key safety observations in the adolescent population from the IRIS trial: mean weight gain of 1.1 kilograms with ML004 versus 1.9 kilograms with placebo, a placebo-adjusted somnolence rate of 11.8%, and no extrapyramidal events observed, consistent with the mechanism of action of ML004.
Project
reported that in the pre-specified adolescent subgroup with clinically significant baseline irritability, ML004 demonstrated a mean change from placebo of 7.2 points and an effect size of 1.0 at approximately 7 weeks of maintenance dosing, increasing to an LS mean difference of 9.6 points with an effect size of 1.33 and a nominally statistically significant p-value by the end of the 12-week maintenance period, with the growing separation over time considered biologically consistent with the mechanism of action.
Medical Research
Person-Based
Medical Research
MapLight Therapeutics News & Media
MapLight Therapeutics Announces Positive Topline Results from Phase 2 ZEPHYR Trial of ML-007C-MA in Schizophrenia
The trial, designed and sized to support registration, met its primary endpoint, with the 210/3 mg BID dose demonstrating a statistically significant improvement in PANSS total score compared to placebo at Week 5 with an effect size of 0.37 (LS mean difference vs PBO -4.5, p=0.015)MapLight Therapeutics Announces Changes to Board of Directors
SAN FRANCISCO and BOSTON, June 24, 2026 (GLOBE NEWSWIRE) -- MapLight Therapeutics, Inc. (Nasdaq: MPLT), a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system (CNS) disorders, today announced the appointment of Martin Babler and Troy Cox to its Board of Directors following their election at the Company’s Annual Meeting of Stockholders on June 23, 2026. Mr. Babler and Mr. Cox succeed Robert Malenka, M.D., Ph.D., andMapLight Therapeutics, Inc. (MPLT) Discusses Top Line Phase II IRIS Study Results for ML-004 in Autism Spectrum Disorder Transcript
MapLight Therapeutics, Inc. (MPLT) Discusses Top Line Phase II IRIS Study Results for ML-004 in Autism Spectrum Disorder June 22, 2026 8:00 AM EDTCompany...MapLight Announces Topline Results from Phase 2 IRIS Study for ML-004 in Autism Spectrum Disorder
SAN FRANCISCO and BOSTON, June 22, 2026 (GLOBE NEWSWIRE) -- MapLight Therapeutics, Inc. (Nasdaq: MPLT), a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system disorders, today announced topline results from IRIS (ML-004-002), a Phase 2 study of ML-004 in autism spectrum disorder (ASD). The study randomized 161 participants (102 adolescents, 59 adults), with prespecified analyses planned by age group and baseline ir
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MapLight Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system disorders. The company was founded by globally recognized leaders in psychiatry and neuroscience research to address the lack of circuit-specific pharmacotherapies available for patients.... Read More
