Libbrecht Lab

Libbrecht Lab is a research group based in the School of Computing Science at Simon Fraser University. The lab develops and applies machine learning methods for genomics to uncover genotype-phenotype relationships, specifically determining how DNA base pair sequences relate to individual traits and diseases. The group utilizes probabilistic graphic... al models, deep neural networks, and convex and submodular optimization to analyze biological data sets, including DNA sequences, single cell genomics, flow cytometry, and epigenetic data such as ChIP-seq and ATAC-seq. Its research focuses on annotating the epigenome, learning genomic representations, predicting drug resistance in pathogenic bacteria, and developing methods for the normalization and selection of genomic data.Read More