Fractyl Health
Highly Engaged Employees
Highly Engaged EmployeesManufacturing · Massachusetts, United States · 51-200 Employees
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Overview
Headquarters
3 Van De Graaff Dr Ste 200, Burlington, ...Phone Number
(781) 902-8817Website
www.fractyl.comRevenue
<$5 MillionStock Symbol
GUTSIndustry
ZI Rank: 1
Signal Type
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ZI Rank
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About Fractyl Health
Fractyl Health is focused on pioneering a new approach to the treatment of T2D. Despite advances in treatment over the last 50 years, metabolic diseases in general, and T2D in particular, continue to be a principal and rapidly growing driver of morbidity and mortality in the 21st century. Fractyl Health's goal is to transform T2D treatment from chronic blood glucose management to disease-modifying therapies that target the organ-level root causes of the disease. Fractyl Health's lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e., duodenal mucosal resurfacing) in order to edit abnormal intestinal nutrient sensing and signaling mechanisms that are a potential root cause of metabolic diseases.Explore more
Fractyl Health Org Chart
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Revenue
Number of Employees
Type
Funding
Founded In
$7.5M
11-50
Private
$35.9M
2013
RS
Robert SokolowskiVice President, Clinical, Quality & Regulatory Affairs
Company Profile Activity
Activity Insights
Fractyl Health is experiencing very low activity levels compared to other companies in the Manufacturing sector.
What does this means?
Fractyl Health is drawing exceptional interest within the Manufacturing industry, suggesting notable developments or strong market momentum, learn more about Fractyl Health.
Fractyl Health financials insights
Gather financial insights about Fractyl Health, including details on funding rounds, investors, total funding, and acquisitions, to gain a comprehensive understanding of their financial strategy.
2013
Series A
$14.3M
2015
Series C
$57M
2017
Series D
$44M
2020
Series E
$55M
2021
Series F
$100M
2024
Stock Offering
$110M
Fractyl Health Tech Stack
A closer look at the technologies used by Fractyl Health
Most Recent Scoops
Project
Fractyl Health has reported that both co-primary endpoints in its pivotal study are powered at over 95%, with the first endpoint measuring percent total body weight regain in Revita versus Sham at 6 months and the second being a responder rate endpoint requiring at least 50% of patients to maintain at least 5% of total body weight loss at 12 months a threshold achieved by 73% of the MITT population and over 90% of the complete ablation cohort.
Medical Research
Project
Fractyl Health has observed a clear dose response in the Remain One Midpoint Cohort, with patients receiving more complete duodenal ablation maintaining significantly more weight at 6 months, leading the company to define the per-protocol population in its pivotal study as those who received a complete ablation of more than 14 centimeters.
Medical Research
Person-Based
Product Development, Medical Research, Pharmaceuticals
Person-Based
Research & Development, Pharmaceuticals, Clinical Operations
Person-Based
Medical Research, Pharmaceuticals, Clinical Operations
Fractyl Health News & Media
Fractyl Health to Participate in Upcoming Investor Events
BURLINGTON, Mass., July 22, 2026 (GLOBE NEWSWIRE) -- Fractyl Health, Inc. (Nasdaq: GUTS) (the Company or Fractyl), a clinical-stage metabolic therapeutics company focused on pioneering novel approaches to treat obesity and type 2 diabetes (T2D), today announced that Harith Rajagopalan, M.D., Ph.D., Co-Founder and Chief Executive Officer of the Company, will be participating in the following upcoming investor conferences:Fractyl Health, Inc. (GUTS) Discusses 1-Year REMAIN-1 Data Demonstrating Durable Weight Maintenance After GLP-1 Discontinuation Transcript
Fractyl Health, Inc. (GUTS) Discusses 1-Year REMAIN-1 Data Demonstrating Durable Weight Maintenance After GLP-1 Discontinuation July 15, 2026 8:00 AM...Fractyl Health Reports Positive Randomized Data from REMAIN-1 Midpoint Cohort Demonstrating Durable Weight Maintenance One Year After GLP-1 Discontinuation
Up to 84% of GLP-1 induced weight loss retained with Revita® versus 46% with sham at one year in patients receiving complete duodenal ablationsFractyl Health Reports Positive One-Year REVEAL-1 Open-Label Results Showing Sustained Post-GLP-1 Weight Maintenance After a Single Revita® Procedure
Participants retained ~78% of GLP-1 induced total body weight loss one year after discontinuation and a single Revita procedure
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Fractyl Health is focused on pioneering a new approach to the treatment of T2D. Despite advances in treatment over the last 50 years, metabolic diseases in general, and T2D in particular, continue to be a principal and rapidly growing driver of morbidity and mortality in the 21st century. Fractyl Health's goal is to transform T2D treatment from chr... Read More
