Fractyl Health
Highly Engaged Employees
Highly Engaged EmployeesManufacturing · Massachusetts, United States · 51-200 Employees
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Overview
Headquarters
3 Van de Graaff Dr Ste 200, Burlington, ...Phone Number
(781) 902-8817Website
www.fractyl.comRevenue
<$5 MillionStock Symbol
GUTSIndustry
ZI Rank: 1
Signal Type
Mar
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ZI Rank
1
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About Fractyl Health
Fractyl Health is focused on pioneering a new approach to the treatment of T2D. Despite advances in treatment over the last 50 years, metabolic diseases in general, and T2D in particular, continue to be a principal and rapidly growing driver of morbidity and mortality in the 21st century. Fractyl Health's goal is to transform T2D treatment from chronic blood glucose management to disease-modifying therapies that target the organ-level root causes of the disease. Fractyl Health's lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e., duodenal mucosal resurfacing) in order to edit abnormal intestinal nutrient sensing and signaling mechanisms that are a potential root cause of metabolic diseases.Explore more
Fractyl Health Org Chart
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Revenue
Number of Employees
Type
Funding
Founded In
$7.5M
11-50
Private
$35.9M
2013
RS
Robert SokolowskiVice President, Clinical, Quality & Regulatory Affairs
Company Profile Activity
Activity Insights
Fractyl Health is experiencing very low activity levels compared to other companies in the Manufacturing sector.
What does this means?
Fractyl Health is drawing exceptional interest within the Manufacturing industry, suggesting notable developments or strong market momentum, learn more about Fractyl Health.
Fractyl Health financials insights
Gather financial insights about Fractyl Health, including details on funding rounds, investors, total funding, and acquisitions, to gain a comprehensive understanding of their financial strategy.
2013
Series A
$14.3M
2015
Series C
$57M
2017
Series D
$44M
2020
Series E
$55M
2021
Series F
$100M
2024
Stock Offering
$110M
Fractyl Health Tech Stack
A closer look at the technologies used by Fractyl Health
Most Recent Scoops
Person-Based
Medical Research, Clinical Operations
Project
Fractyl Health has reported 1-year randomized data from the REMAIN-1 midpoint cohort, showing that Revita patients maintained more than 80% of their prior GLP-1-induced weight loss at 1 year, compared with 46% in the sham arm, with the treatment effect sustained from month 6 through month 12 under maintained blinding in a cohort where no patient reinitiated GLP-1 therapy.
Medical Research
Project
Fractyl Health has reported no safety signals from its pilot studies of Revita, with patients experiencing only mild, rare, and transient side effects for a couple of days following the procedure, and the mucosal lining healing within weeks.
Medical Research, Clinical Operations
Project
Fractyl Health has identified that patients who lose the most weight on GLP-1 drugs demonstrate the largest effect size from Revita, an observation that has been incorporated into the pre-specified statistical analysis plan, which has been cleared with the FDA.
Medical Research, Pharmaceuticals
Project
Pharmaceuticals, Clinical Operations
Fractyl Health News & Media
GUTS Shareholder Alert: Investors With Losses May Seek to Lead the Class Action in Fractyl Health, Inc. Securities Lawsuit - Contact Levi & Korsinsky
Fractyl Health told investors in September 2025 that Revita-treated patients lost an additional 2.5% of body weight after stopping GLP-1 drugs; four months later the Company reported 4.5% weight regain, and GUTS shares closed at $0.46 Fractyl Health told investors in September 2025 that Revita-treated patients lost an additional 2.5% of body weight after stopping GLP-1 drugs; four months later the Company reported 4.5% weight regain, and GUTS shares closed at $0.46Bronstein, Gewirtz & Grossman LLC Urges Fractyl Health, Inc. Investors to Act: Class Action Filed Alleging Investor Harm
New class action for Fractyl (GUTS) urges investors to seek recovery for alleged securities fraud violations – lead plaintiff deadline of 10/20/2026GUTS Investor Alert: Fractyl Health, Inc. Securities Class Action Notice - Contact SueWallSt
Allegations center on operational failures at one of six REMAIN-1 Midpoint Cohort clinical sites, which the complaint contends skewed Revita DMR weight maintenance data that Fractyl Health promoted to investors. NEW YORK, Sept. 24, 2026 /PRNewswire/ -- SueWallSt reminds purchasers of...SHAREHOLDER ALERT Bernstein Liebhard LLP Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Fractyl Health, Inc. (GUTS)
Fractyl Health Shareholders Between January 13, 2025 and January 29, 2026 - Contact Bernstein Liebhard For More Information Regarding Lawsuit
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Frequently Asked Questions Regarding Fractyl Health
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Fractyl Health is focused on pioneering a new approach to the treatment of T2D. Despite advances in treatment over the last 50 years, metabolic diseases in general, and T2D in particular, continue to be a principal and rapidly growing driver of morbidity and mortality in the 21st century. Fractyl Health's goal is to transform T2D treatment from chr... Read More
