Biocleave

At biocleave we are using our position as clostridial experts to exploit the protein production capabilities of these versatile microbes. Researchers are often constrained by the prohibitive cost of biological reagents and we aim to provide higher quality products at an affordable price. Although our main focus is on life science research, our prot... eins and enzymes have a range of applications across multiple markets. Our core market is research use only (RUO) proteins, for the study of multiple cellular activities such as cell signalling, replication, transcription, and translation. Our proprietary technology, coupled with the unique characteristics of clostridia, enable us to overcome the typical protein expression challenges of production host toxicity and costly development cycles. Robust industrially proven strains with in-house fermentation expertise and scale up capabilities. We own an extensive and diverse strain collection and have over 15 years of experience in engineering, adapting and fermenting clostridia. Understanding the biochemistry and physiology of these microbes is key to exploiting them for novel applications. We were the first to use endogenous CRISPR-Cas for genome editing in clostridia and our patented, proprietary technology CLEAVE is at the heart of our company. You need the right expertise to work with clostridia. We have developed the technology and the toolkits to make cloning and expression protocols, typically only established in model organisms, fast and efficient in clostridia. Want to know more about biocleave? Want to know more about biocleave?Read More