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Michele M. Kosiewicz

University of Louisville Research Foundation , KY

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University of Louisville Research Foundation , KY

Web References(18 Total References)


LRI Grant Recipients by State | Lupus Research Institute

Michele M. Kosiewicz, PhD
University of Louisville Research Foundation, KY


Michele M. Kosiewicz, PhD | Lupus Research Institute

Michele M. Kosiewicz, PhD
University of Louisville Research Foundation, KY Dr. Kosiewicz has made breakthroughs in this area, finding that in female mice with lupus, the number (and function) of a type of white blood cell that prevents autoimmune disease-regulatory T cells-is significantly lower than in male mice with lupus. Female mice given male sex steroids (androgens) actually experience an increase in the level and function of these T cells-and protection against the disease. By clarifying the role of regulatory T cells in preventing lupus and the mechanisms by which androgens enhance their action, Dr. Kosiewicz aims to unveil new treatment strategies.


Michele M. Kosiewicz, PhD | Lupus Research Institute

Michele M. Kosiewicz, PhD
University of Louisville Research Foundation, KY Dr. Kosiewicz has made breakthroughs in this area, finding that in female mice with lupus, the number (and function) of a type of white blood cell that prevents autoimmune disease-regulatory T cells-is significantly lower than in male mice with lupus. Female mice given male sex steroids (androgens) actually experience an increase in the level and function of these T cells-and protection against the disease. By clarifying the role of regulatory T cells in preventing lupus and the mechanisms by which androgens enhance their action, Dr. Kosiewicz aims to unveil new treatment strategies.


Kosiewicz | Lupus Research Institute

Michele M. Kosiewicz, PhD
University of Louisville Research Foundation, KY Dr. Kosiewicz has made breakthroughs in this area, finding that in female mice with lupus, the number (and function) of a type of white blood cell that prevents autoimmune disease-regulatory T cells-is significantly lower than in male mice with lupus. Female mice given male sex steroids (androgens) actually experience an increase in the level and function of these T cells-and protection against the disease. By clarifying the role of regulatory T cells in preventing lupus and the mechanisms by which androgens enhance their action, Dr. Kosiewicz aims to unveil new treatment strategies.


Lupus Research Institute

Michele M. Kosiewicz, PhDUniversity of Louisville Research Foundation, Kentucky


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