Charles Reynolds

Charles F. Reynolds

Director at University of Pittsburgh

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3025 E. Carson Street, Pittsburgh, Pennsylvania, United States
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General Information


CME Outfitters LLC

President  - American Association for Geriatric Psychiatry

Doctor of Medicine Degree  - Yale University


M.D.  - Dean University of Pittsburgh School of Medicine

MD  - Graduate School of Public Health

MD  - University of Pittsburgh Medical Center

MD  - Western Psychiatric Institute

MD  - Yale

bachelor's degree  - philosophy , University of Virginia


Director, Aging Institute of UPMC Senior Services and the University of Pittsburgh  - UPMC Health Plan Inc

Endowed Professor In Geriatric Psychiatry, Professor of Behavioral and Community Health Sciences  - Pitt Community College


Member  - Pennsylvania Long-term Care Commission and the Pennsylvania Alzheimer's Disease State Planning Committee

UPMC Endowed Professor In Geriatric Psychiatry, Board Member  - Pittsburgh Pastoral Institute

Advisory Board Member  - The Center for Complicated Grief

Member  - Pennsylvania Alzheimer's Disease State Planning Committee

Board Member  - University of Pittsburgh Institute

Advisory Board Member  - MedEd Mentoring

Scientific Advisory Board Member  - Depression and Bipolar Support Alliance

Lifetime Member  - International Psychogeriatric Association

Member of Advisory Board  - Cypress Bioscience , Inc.

Study Panel Member  - Institute of Medicine

Board of Trustees Member  - Minnesota Medical Association

Chairman and Member of Several Research Review Committees  - National Institute of Mental Health

Founder  - Global Consortium on Depression Prevention

Credentials Committee  - American College of Neuropsychopharmacology

Recent News  

Charles F. Reynolds III, MD
Endowed Professor of Geriatric Psychiatry University of Pittsburgh School of Medicine

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"The good news is that, notwithstanding the burden of chronic mental illness, depression is treatable," said Charles F. Reynolds III, professor of psychiatry and neuroscience at the University of Pittsburgh and lead author of the new study.
He said the beneficial effects of psychotherapy shown in the study particularly surprised him. About 57 % of patients given the drug alone were able to fend off depression for three years, compared with 80% on both the drug and psychotherapy and 36% on psychotherapy with placebo. "What really comes out is the advantage for combined treatment," he said. The report, funded by the National Institute of Mental Health, appears in today's Journal of the American Medical Association. Nortriptyline is one of a class of antidepressants known as tricyclics that were the, leading treatment for depression before Prozac and other so-called selective serotonin reuptake inhibitors, SSRl's, became popular during the past decade. Dr. Reynolds said the study, the first randomized trial to compare various treatment strategies against a placebo for depression in the elderly, was launched in 1989, before the new class of medicines became well established. He said his research group is now testing SmithKline Beecham PLC's SSRI, Paxil, in a trial similar to the current study. Nortriptyline is marketed as Pamelor by Novartis AG, and in generic forms by two other companies. Dr. Reynolds said the study wasn't funded by any pharmaceutical companies. The findings serve to underscore some barriers to effective treatment for depression in the elderly. Traditional Medicare reimbursement doesn't cover prescription drugs, and Dr. Reynolds noted that both Medicare and managed health-care plans that serve Medicare patients tend to limit psychotherapy visits. "We would like to argue that investing a little bit of resources to help older people wrestle with depression, bereavement and issues such as retirement may be very good for the national health care budget," he said.

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Charles F. Reynolds III, MD
Dr. Reynolds is a professor of geriatric psychiatry, neurology and neuroscience, and behavioral and community health sciences at the University of Pittsburgh Graduate School of Public Health. Dr. Reynolds is internationally renowned in the field of geriatric psychiatry. His primary research interests focus on mood and sleep disorders of later life, with a particular focus on treatment (including mental health services in primary care, the mechanisms of treatment response, preventative interventions and suicide prevention.) Dr. Reynolds directs the Advanced Center for Interventions and Services Research for Late-Life Mood Disorders for the Study of Late-Life Mood Disorders at the Western Psychiatric Institute and Clinic, the John A. Hartford Center of Excellence in Geriatric Psychiatry and three NIMH-funded Research Training Grants. Dr. Reynolds graduated magna cum laude from the University of Virginia before earning his medical degree from Yale University School of Medicine in 1973. He then completed a straight medical internship at the Royal Victoria Hospital and Montreal Neurological Hospital and continued on to post-graduate work in adult and geriatric psychiatry, sleep disorders and clinical electroencephalography at the Western Psychiatric Institute and Clinic. The recipient of a National Institute of Mental Health (NIMH) Research Scientist Award and a MERIT award for Maintenance Therapies in Late-Life Depression, Dr. Reynolds has twice been named one of The Best Doctors in America. Dr. Reynolds chaired the planning committee for the 1991 NIH consensus development conference on the Diagnosis and Treatment of Depression in Late-Life and the 2001 NDMDA consensus conference on Unmet Needs in the Diagnosis and Treatment of Late-Life Mood Disorder. In addition to serving on the Institute of Medicine Study of the Pathophysiology and Prevention of Adolescent and Adult Suicide, Dr. Reynolds has served as chairman and member of several research review committees at the NIMH. He is currently a member of the National Advisory Mental Health Council of the NIMH and has served as President of the American College of Psychiatrists and the International College of Geriatric Psychoneuropharmacology. Dr. Reynolds' bibliography contains over 400 publications in peer-reviewed journals, which he has written over the past 31 years. The associate editor of American Journal of Geriatric Psychiatry, Dr. Reynolds has also served on the editorial board of several nueropsychiatric, gerontology and sleep journals including the American Journal of Psychiatry and Neuropsychopharmacology.

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