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Dr. Tian Xu

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Yale University
New Haven, Connecticut
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    www.eurekalert.org/pub_releases/2008-09/tcob-fsr091208. - [Cached Version]
    Published on: 9/17/2008    Last Visited: 9/17/2008  

    Tian Xu and colleagues at the Yale University School of Medicine examined the activity of hemocytes, a type of immune cell, in response to genetically-induced tumor growth in the fruit fly Drosophila.
    ...
    Commentary on this work by researcher Tian Xu will be featured in the DMM Podcast for issue 2/3 of DMM.Podcasts are available via the DMM website at: dmm.biologists.org.

    The report was written by José Carlos Pastor-Pareja, Ming Wu, and Tian Xu of the Yale University School of Medicine, New Haven, CT.

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    www.sanluisobispo.com/health/story/310050.html - [Cached Version]
    Published on: 3/20/2008    Last Visited: 3/20/2008  

    For example, Tian Xu, a geneticist at the Yale School of Medicine, studies how cancerous cells in flies metastasize, or spread to other cells, similar to the way they do in human malignant tumors.

    "Our fly model has distinct advantages for studying the basic biology underlying tumor progression and metastasis," Xu wrote on his Web site.

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    www.UCForum.org/bios.asp?bid=tian - [Cached Version]
    Published on: 3/23/2007    Last Visited: 1/29/2008  

    Dr. Tian Xu

    Tian Xu is a Professor of Genetics, Molecular Oncology and Development at Yale University and an Investigator of the Howard Hughes Medical Institute in USA.Prof. Xu also serves as the Vice Chair of the Department of Genetics at the Yale School of Medicine.In 2003 he was appointed as Special Advisor to the President of Yale University on Science and Higher Education in China.

    Since 1996, Prof. Xu has also taught at Fudan University in Shanghai and is the director of the Fudan-Yale Biomedical Research Center at Fudan University, alternately known Institute of Developmental Biology and Molecular Medicine.He serves as a Special Advisor to the President of Fudan University, an overseas assessor for the Chinese Academy of Sciences, and the Chairman of the Scientific Advisory Board for the Rothberg Institute for Childhood Diseases.Prof. Xu formerly served as the President of the Chinese Bioscience Investigator Society and also as the chair and a member of the U.S. National Academy Committee on the Conference of the U.S.-China Frontier of Sciences from 1997 to 2000.

    Prof. Xu uses model organisms to understand the molecular mechanism of development and human disease.He is the inventor of the genetic mosaic screen and the mammalian PB transposon system and holds multiple patents.He is the receipt of multiple awards including the Helen Hay Whitney fellow, Pew Scholar, Tuberous Sclerosis Alliance Rothberg Courage Award, Science and Technology Award of Chinese Higher Education.

    Prof. Xu received his B.S. from Fudan University in 1982, his Ph.D. from Yale University in 1990, and his postdoctoral training at University of California at Berkeley.

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    www.uwire.com/Article.aspx?id=3062156 - [Cached Version]
    Published on: 9/3/2008    Last Visited: 9/6/2008  

    "We already have a physical map to work with," said Tian Xu, vice chairman of the Department of Genetics at the School of Medicine.
    ...
    Come the move to West Campus, scientists will set up a laboratory Xu called Mouse Clinic, dedicated to mutating mammalian genes using this technique.

    But the puzzle of genomic functionality is not as simple as "one-gene-one-function."Far from having consistent or singular functions in cells, genes interact with other genes in complex pathways, are continuously influenced by the environment and even appear to have different functions in different contexts, Xu said.
    ...
    "There's a spectrum: All diseases have some genetic basis, but some diseases are more clearly genetic," Xu said.

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    www.xiaoyuanlife.com/html/yingyusiji/20090620/402.html - [Cached Version]
    Published on: 6/20/2009    Last Visited: 7/29/2009  

    Yale professor and Howard Hughes Medical Institute investigator Tian Xu directs a research center focused on the genetics of human disease at Shanghai's Fudan University, in collaboration with faculty colleagues from both schools. The

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    www.cet4u.com/sijizhenti/03/1206804680.html - [Cached Version]
    Published on: 7/13/2008    Last Visited: 7/13/2008  

    Yale professor and Howard Hughes Medical Institute investigator Tian Xu directs a research center focused on the genetics of human disease at Shanghai's Fudan University, in collaboration with faculty colleagues from both schools.

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    www.yalealumnimagazine.com/issues/2005_11/findings.html - [Cached Version]
    Published on: 1/1/2005    Last Visited: 8/13/2009  

    The jumping gene system "provides a tremendous tool," says Tian Xu, professor and vice chair of genetics at Yale's School of Medicine. "By looking at what goes wrong, we can understand what the gene we've tampered with normally does."

    Scientists had searched in vain for 30 years for a transposon that they could easily manipulate in vertebrates. Xu's team tried a long shot: a moth transposon whimsically named piggyBac.

    Xu has now shown that piggyBac can remain stable in human and mouse cell lines and through five generations of mice, a discovery that has considerable promise for both basic and applied science. Over the last three decades, scientists have elucidated the functions of only ten percent of the mouse genome. In the next three years, Xu and colleagues at Fudan plan to use piggyBac to determine the remaining 90 percent.

    Equally important, the transposon can also carry novel genes into the genome. This ability has enabled Xu and his team to put human tumor-suppressing genes into mice to learn how tumors grow and how they may be stopped.

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    www.yalealumnimagazine.com/issues/2004_05/q_a.html - [Cached Version]
    Published on: 1/1/2004    Last Visited: 6/7/2009  

    There's the Yale-Fudan genetics center, with 150 researchers led by Yale professor Tian Xu.
    ...
    And the answers President Xu and I gave were quite different.

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    www.UCForum.org/index.asp?pg=agenda - [Cached Version]
    Published on: 3/23/2007    Last Visited: 1/29/2008  

    Tian Xu (Moderator), Professor of Genetics, Molecular Oncology and Development; Vice Chair, Department of Genetics at Yale University; and Investigator, Howard Hughes Medical Institute.

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    www.UCForum.org/index.asp?pg=speaker - [Cached Version]
    Published on: 3/23/2007    Last Visited: 1/29/2008  

    Tian Xu, Professor of Genetics, Molecular Oncology and Development; Vice Chair, Department of Genetics at Yale University; and Investigator, Howard Hughes Medical Institute.

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