Dr. Ting Xie

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  www.eurekalert.org/pub_releases/2009-06/sifm-xlu062609. - [Cached Version]
  Published on: 6/26/2009    Last Visited: 6/27/2009  

  "Our studies have established the role of BAM as a protein translational repressor using biochemical and genetic tests," said Ting Xie, Ph.D., Investigator and senior author on the paper.
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  Ting Xie, Ph.D., Investigator, also is a Professor in the Department of Anatomy & Cell Biology at The University of Kansas School of Medicine. Learn more about his work at www.stowers.org/labs/XieLab.asp.

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  paz.zubilokk.com/fouled_anchor.html - [Cached Version]
  Published on: 7/6/2008    Last Visited: 7/6/2008  

  Ting Xie also holds an academic appointment as an Associate Professor in the Department of Anatomy & Cell Biology at KU Medical School.

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  www.cell-research.com/news/C4P.html - [Cached Version]
  Published on: 9/1/2006    Last Visited: 3/28/2007  

  Ting Xie, PhD, Professor, Stowers Institute for Medical Research, Kansas City, MO 64110, USA.tgx@Stowers-Institute.org

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  www.simr.org/whatsnew/PR1997-2002/XieSciencePaper.htm - [Cached Version]
  Published on: 6/6/2002    Last Visited: 8/29/2009  

  Research conducted in the laboratory of Ting Xie, Stowers Institute Assistant Scientist, shows that DE-cadherin-mediated cell adhesion, or "cell glue," helps stem cells find their niche, and then anchors them in place so that they can receive these vital instructions.
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  As we learn more about how stem cells are first attracted to and then kept in their niche, we are better able to assess their structure, function and maintenance," Xie said.
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  Xie's research demonstrates that the microenvironment is more important than the stem cell itself in determining its fate, information that lends hope to the thought that stem cells from any organ may be able to replace damaged cells in another organ if they find themselves in that organ's stem cell niche."
  
  This discovery builds upon previous research by Ting Xie and Allan Spradling at the Carnegie Institution of Washington, which demonstrated that stem cell function is regulated by environmental factors.

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  www.gerntalk.com/Blog2.asp?varBlogID=1931 - [Cached Version]
  Published on: 5/26/2009    Last Visited: 7/4/2009  

  Associate Investigator Ting Xie, Ph.D., does research on adult stem cells at the Stowers Institute for Medical Research in Kansas City, Mo., on Feb. 14, 2005. (Charlie Riedel/Associated Press)

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  www.simr.org/WhatsNew/pr2005/PR120105.asp - [Cached Version]
  Published on: 12/1/2005    Last Visited: 3/25/2007  

  Kansas City, Mo. (Dec. 1, 2005) - Rongwen Xi, Postdoctoral Research Associate, and Ting Xie, Associate Investigator, have identified two chromatin remodeling factors involved in controlling stem cell populations.
  
  The findings were published in the Dec. 2, 2005 issue of Science.
  
  Although the stem cell niche - the microenvironment surrounding a stem cell - and its associated signals are known to be important for controlling stem cell populations, it remains largely unclear how these signals are interpreted by the stem cell at the level of gene expression.
  
  Chromatin remodeling factors are important for controlling gene expression by modulating the chromatin structure in which an individual gene is buried.In this study, Dr. Xie's team identified two chromatin remodeling factors - ISWI and Domino.Each is involved in controlling self-renewal and proliferation of stem cell populations.This study also shows that different stem cell populations require different chromatin factors to help interpret the signals sent by niches.
  
  "I believe that we must truly understand fundamental aspects of stem cell regulation in tissues before we are able to harness their full power in regenerative medicine," said Dr. Xie."This work contributes to the fundamental understanding of stem cell regulation.The information gained from this kind of study will enhance our ability to use stem cells in future therapeutic applications."
  
  "Dr. Xie's team has identified chromatin remodeling factors as important components in allowing stem cells to translate and interpret signals from their niche," said Robb Krumlauf, Ph.D., Scientific Director.
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  More information about Dr. Xie's lab group can be found at http://www.stowers-institute.org/labs/XieLab.asp.

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  www.grc.org/programs.aspx?year=2007&program=devbio - [Cached Version]
  Published on: 6/21/2007    Last Visited: 8/16/2007  

  Ting Xie (Stowers)

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  www.simr.org/WhatsNew/pr2009/PR062609.asp - [Cached Version]
  Published on: 6/26/2009    Last Visited: 8/29/2009  

  "Our studies have established the role of BAM as a protein translational repressor using biochemical and genetic tests," said Ting Xie, Ph.D., Investigator and senior author on the paper. "Translational control is very important in regulating gene expression. Many genes critical for stem cell development in the fruit fly germline are suggested to be translational regulators, but their exact roles have not been carefully studied. The knowledge generated by this work and the tests we have developed give us great advantage in tackling many additional questions."
  
  Ting Xie, Ph.D., Investigator, also is a Professor in the Department of Anatomy & Cell Biology at The University of Kansas School of Medicine. Learn more about his work at http://www.stowers.org/labs/XieLab.asp.

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  www.sciencedaily.com/releases/2007/12/071213121001.htm - [Cached Version]
  Published on: 1/1/2007    Last Visited: 12/14/2007  

  MicroRNA Pathway Essential For Controlling Self-renewal Of Stem Cells (Feb. 20, 2007) , Ting Xie, Ph.D., associate investigator, and Zhigang Jin, Ph.D., postdoctoral research associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling ... > read more

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  cellnews-blog.blogspot.com/2007_02_01_archive.html - [Cached Version]
  Published on: 2/1/2007    Last Visited: 1/28/2008  

  Kansas City, Mo. (Feb. 15, 2007) - Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.
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  "We are in the process of identifying the microRNAs that are important for stem cell self-renewal," said Dr. Xie."Understanding the mechanisms controlling stem cell self-renewal will be crucial to our developing the ability to expand stem cell populations for performing tissue repair."Dr. Xie holds a faculty appointment as an Associate Professor in the Department of Anatomy & Cell Biology at The University of Kansas School of Medicine.

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