Breast Cancer News Article -
[Cached Version]
Published on: 12/26/1999
Last Visited: 3/12/2001
That's why this matters , said Dr. Richard White , a Carolinas Medical Center surgeon who has performed nearly 50 sentinel node biopsies.
Many of our treatment decisions are based on that.If you get the wrong information , you potentially are doing harm..
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In melanoma , if the sentinel nodes are negative , the likelihood of there being cancer in other nodes is less than 1 percent , according to White.If the sentinel nodes are positive , the likelihood of spread is 20 percent to 30 percent.
Because of the success with melanoma , researchers are now evaluating the use of sentinel node biopsy in other tumors , such as breast and thyroid cancer.
Here is how it works :.
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White , who has co-written a textbook chapter on sentinel node biopsy , said early evidence suggests that the procedure accurately predicts whether the cancer has spread , but that's not certain.
The procedure is difficult to do , and even proficient surgeons can get false negatives.In one study published in the New England Journal of Medicine in 1998 , one in 10 patients with cancer-free sentinel nodes was found to have cancer in other underarm nodes.
If you don't take out the rest of the nodes ( to compare them to the sentinel nodes ) , you don't know what your false negative rate is , White said.
It may turn out that this will be a better technique in the right hands but it's not `Zim-bang , we've got a new thing , everybody should go and get this.'.