abstract04.tctmd.com/Show.aspx?id=66928 -
[Cached Version]
Published on: 3/30/2008
Last Visited: 3/30/2008
"PCI is associated with myonecrosis in about 25 percent of patients with non-STEMI acute coronary syndromes," said Mark W.I. Webster, MD, director of the cardiac catheterization laboratory at Auckland CityHospital, Auckland, New Zealand.
...
For the study, Dr. Webster and his colleagues recruited 151 patients treated at 14 medical centers in New Zealand, Australia and Canada, randomly assigning them to protection with the FilterWire or to conventional PCI without vascular protection.The researchers found that the rates of major cardiovascular complications during hospitalization -- consisting of death, heart attack, emergency bypass surgery, or repeat procedure in the treated artery -- were no different in the two groups (12 percent in the FilterWire group vs.10 percent in the control group).There were also no significant differences between the groups in the post-procedure release of enzymes that signal damage to the heart muscle.
"The device does not appear warranted for routine use in these patients," Dr. Webster said."However, there are some patients who have major complications from distal embolism.We need better ways of identifying high-risk patients and lesions."
Dr. Webster will present the results of the "Angioplasty Balloon-Associated Coronary Debris and the EZ FilterWire" (A-F) study on Sunday, March 30 at 8:00 a.m. CDT in the Grand Ballroom, S100.