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Last Visited: 10/5/2007
"Coatings have traditionally been studied using complex tools such as IR [infra red] and Raman spectroscopy, but this quick optical microscope-based thermal analysis method makes coating analysis much easier," said Roshan Shetty, CEO of Anasys.
According to a review published in the Journal of Pharmaceutical Sciences, the micro-TA "has the potential ability to not only discriminate between different materials, or indeed physical forms [of a compound such as polymorphs] within a multicomponent system, but also the ability, to perform characterisation studies."
The review continues by stressing how important this could be as the majority of solid-state dosage forms are composite formulations.
"One of the potential applications for the Vesta is studying coatings and checking there are no imperfections that could lead to faster than desired drug release," said Shetty
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"The traditional complexity with nano-TA was associated with acquiring the AFM image and interpreting it," said Shetty.