www.lifescript.com/news/reuters/Pig_gut_implant_a_lip_p -
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Published on: 1/23/2008
Last Visited: 1/30/2008
"We think there is a viable product here," Dr. Edmund A. Pribitkin of Thomas Jefferson University in Philadelphia told Reuters Health.However, he noted, just one implant wasn't enough to satisfy half of the patients in the small study.
The implant Pribitkin and his team studied, Surgisis, is derived from the lining of the small intestine of pigs, and made by West Lafayette, Indiana-based Cook Biotech Inc.It is approved by the U.S. Food and Drug Administration and has been shown to be safe and effective when used in other parts of the body.
Other approaches to augmenting lips have drawbacks.Injections like Restylane gradually dissolve, Pribitkin noted, while other implants such as Gore-Tex may kink and curl.Ideally, he explained, the Surgisis implant would act as a scaffold for renewed growth of the patient's own tissue, dissolving over time.
"What would ideally happen is that it would be replaced by the body's own tissue," he said.
He and his colleagues implanted eight patients with one strand of the material per lip.Under local anesthesia, the researchers made entry and exit incisions for the implant on either side of the lip, after which they inserted the implant and closed the incisions with a single stitch each.
"Short-term lip augmentation was achieved in all 8 patients," he and his colleagues report.Four patients requested an additional implant upon follow up, while one of them required a third.
Only one patient developed an infection after the procedure.
Pribitkin and his team are conducting additional studies of Surgisis to treat folds and wrinkles in the face, as well as longer-term follow-up of patients who underwent lip augmentation."We think it gives an alternative to people who are getting injections," he concluded.
Pribitkin has worked as a paid consultant for Cook Biotech, but the company did not fund the current study.