Dr. Francoise Perdreau-Remington

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  www.principalhealthnews.com/topic/mmmrsa - [Cached Version]
  Published on: 6/20/2008    Last Visited: 9/4/2008  

  Interview with Francoise Perdreau Remington, PhD, MRSA expert and professor emerita at UCSF Medical School, epidemiologist and microbiologist, and longtime director of the molecular epidemiology lab at San Francisco General Hospital.
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  Interview with BP Diep, PhD, researcher and longtime colleague of Dr. Francoise Perdreau Remington

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  www.thetrumpet.com/geo/na/docs/issues/200503/25.asp - [Cached Version]
  Published on: 6/26/2004    Last Visited: 3/22/2005  

  Dr. Francoise Perdreau-Remington, an infectious-disease specialist at the University of California in San Francisco, claims it is "now spreading all over California" (San Jose Mercury News, California, January 26).

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  forum.mrsaresources.com/viewtopic.php?t=1241&highlight= - [Cached Version]
  Published on: 2/3/2008    Last Visited: 2/22/2008  

  The person at San Francisco General hospital tasked with discovering what is going on at a deeper, molecular level is Diep's colleague and co-author, Francoise Perdreau-Remington.The director of the hospital's molecular epidemiology lab, Perdreau-Remington was recruited from a lab in Germany in 1995 specifically for her expertise as a disease detective.Since the late Nineties she's run dozens of studies on bacterial cultures taken from patients at San Francisco General and other city health clinics, in an attempt to identify the mutations in MRSA that confer antibiotic resistance and govern fitness.It was during this screening process that, in March 2001, she became the first person to see the genetic fingerprint of the clone that would become known as USA300.
  
  'I remember it clearly,' she says. 'I thought, "Uh-oh, we have a problem."'
  
  By 2001, San Francisco General was treating so many boils and abscesses in its emergency room that it was forced to open a special clinic exclusively for skin infections.The clone, which at first Perdreau-Remington labelled 'S', had shown up in three cultures taken from patients who attended this walk-in clinic.But when she examined older specimens in cold storage she discovered that the first known 'S' specimen had come from a man who had visited the hospital as early as September 2000.
  
  Perdreau-Remington shared the information with counterparts in Los Angeles County, where inmates of the largest jail system in the US had been complaining of 'spider bites'.On closer examination, these turned out to be staph, and finding the identical genetic fingerprint, Perdreau-Remington sent her findings to the Centers for Disease Control (CDC), which christened the clone USA300.
  
  In December 2007, an outbreak of severe pneumonia in Louisiana and Georgia killed 10 flu patients, including four children.USA300 was also implicated in that outbreak.By now, Perdreau-Remington had won funding to map the bacteria's complete genome.The specimen she picked was one that appeared the most resistant to treatment - a culture that just happened to have been taken in 2003 from the wrist abscess of a 36-year-old man with HIV who was being treated as part of the hospital's 'Positive Health' outreach programme.She did not know it at the time, but the specimen was one of the very first isolates of the highly drug-resistant USA300 variant now circulating in Castro.
  
  The gene map, published in the Lancet in February 2006, was startling.

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  www.astro-shield.com/news_staph_fears.htm - [Cached Version]
  Published on: 1/20/2006    Last Visited: 4/13/2007  

  That piqued the interest of microbiologist Francoise Perdreau-Remington, who works out of a tiny lab at San Francisco General Hospital, where she has collected 7,800 tubes of staph bacteria.
  
  In 2000, Dr. Perdreau-Remington identified the new variant, later dubbed USA300 by the CDC.She describes it as "an epidemic strain that has taken over the market."As part of an unexplained biological trade-off, most bugs weaken as they pick up resistance genes.This one, by contrast, was beating back an increasing number of drugs while at the same time gaining strength.
  
  On a recent day, Dr. Perdreau-Remington pointed to a petri dish in her lab, where a colony of bacteria was busy devouring blood cells.
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  Dr. Perdreau-Remington, the microbiologist, says even if it were possible to test everyone and cleanse them of the bug, patients often get re-infected within six weeks.

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  www.zkea.com/news_archive.html?ARCHIVE=08-04-03 - [Cached Version]
  Published on: 8/4/2003    Last Visited: 8/15/2008  

  "USA300 has a tremendous ability to spread," said Francoise Perdreau-Remington, director of the molecular epidemiology lab at San Francisco General, where the strain was first identified.

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  MRSA Infections, Staph Infection Prevention - [Cached Version]
  Published on: 10/2/2006    Last Visited: 8/8/2008  

  The bacteria, methicillin-resistant Staphylococcus aureus (MRSA), have been identified in 40 U.S. states, said Francoise Perdreau-Remington, professor of medicine at the University of California, San Francisco.
  
  'We found that, in a survey of hospitals in San Francisco a 6.8 percent rate of MRSA among patients and a rate of 8.6 percent of MRSA among individuals in the community,' she said recently at an infectious-disease meeting sponsored by the American Society for Microbiology.
  
  'Community-acquired MRSA is no longer distinguishable from hospital-acquired MRSA,' she said at the 46th annual Interscience Conference on Antimicrobial Agents and Chemotherapy.She said there were facilities in the United States where the MRSA rate exceeds 50 percent of all S. aureus infections.Remarkably, as many as 86 percent of the infections in one hospital are connected to one strain -- called USA 300.
  
  She said that the extension of MRSA into the community in large numbers is alarming.
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  'While screening is expensive, in the end, screening people is less expensive than spreading MRSA infections,' Perdreau-Remington told UPI when asked if the European model of infection control could be exported to the United States. 'We just have to have the will to do it.'

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  Micron Education - 33rd Remington Winter Course in... - [Cached Version]
  Published on: 3/11/2007    Last Visited: 6/1/2007  

  Françoise Perdreau-Remington, PhDProfessorDepartment of Medicine

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  Micron Education - 33rd Remington Winter Course in... - [Cached Version]
  Published on: 3/11/2007    Last Visited: 6/1/2007  

  Community MRSA: The New Reality in Hospitals Today - Francoise Perdreau-Remington, PhD

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  Micron Education - Winter Course in Infectious Diseases - [Cached Version]
  Published on: 2/3/2006    Last Visited: 2/3/2006  

  Francoise Perdreau-Remington, Ph.D.Professor, Department of MedicineDirector, Molecular Epidemiology Research Laboratory

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  Monterey County Herald | 03/05/2006 | Athletes must be... - [Cached Version]
  Published on: 3/5/2006    Last Visited: 3/6/2006  

  One strain, said Francoise Perdreau-Remington, the San Francisco General Hospital professor of infectious diseases, "has reached epidemic proportions in this country."

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