www.eurekalert.org/pub_releases/2008-06/evms-udc061008. -
[Cached Version]
Published on: 6/10/2008
Last Visited: 6/11/2008
The study tested the combination of Lisofylline (LSF), a drug that is being developed to halt immune damage to insulin producing cells, and Islet Neogenesis Associated Protein peptide (INGAP), a drug based on a naturally occurring protein produced by the pancreas. (ADA abstract number: 1620-P Unique Drug Combination for Reversal of Type 1 Diabetes, by Tersey, Carter, Kropf, Rosenberg, Nadler, available online at http://scientificsessions.diabetes.org)
The study was conducted at the University of Virginia by a team of scientists led by Jerry L. Nadler, M.D.Currently Director of Endocrinology and Metabolism at the University of Virginia, Nadler will join the faculty at Eastern Virginia Medical School (EVMS) in July as chair of the Department of Internal Medicine and head of the EVMS Strelitz Diabetes Center.
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"These are very encouraging results," Nadler said."Since both LSF and INGAP are already known to be safe, we should soon be able to begin testing the combination of LSF and INGAP in the clinic as a potential therapy for Type 1 diabetes in people soon."
Nadler was recruited to EVMS as part of a strategic initiative to expand the medical school's research capabilities in four areas where the state's eastern region has specific health needs and EVMS has existing research strengths, including: diabetes, cardiovascular disease, women's health/infant development, and cancer.
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Nadler's work with LSF and INGAP is exactly the kind of innovative new therapy that we want to bring to fruition.
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Dr. Nadler is DiaKine's Chief Scientific Officer.