www.spectrum.ieee.org/oct08/6791 -
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Published on: 9/30/2008
Last Visited: 9/30/2008
This uniformity is important, says Jerome Zhengrong Liang, a radiology professor at Stony Brook's medical school and a member of the team that developed the technique.The software separates the colon from everything else, based on the difference between its density and that of stool and fluid; these differences are indicated by variations in image intensity on the CT scan.Big variations in the stool's consistency might cause the software to mistake fecal matter for part of the colon wall.
Reliably setting the boundary of the colon wall, says Liang, was the team's greatest technical challenge.The software had to screen out artifacts introduced by the CT scan, in particular one known as the partial volume effect.This effect renders extra layers at the places where, say, air and stool meet."The scanner generates values at these points, which might suggest that there's tissue there," says Liang."That might make you think, because of the shape [a lump where the rest of the colon wall is smooth], that you're looking at a polyp when you're not."
But the new software does an even better job of seeing past the artifacts than technology Liang and his colleagues previously patented, reducing the number of false positives by 50 percent.