Dr. Andrea C. King

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  www.drkoop.com/newsdetail/93/286275-29.html - [Cached Version]
  Published on: 3/23/2009    Last Visited: 3/27/2009  

  "Persons with the heaviest drinking patterns appeared to benefit the most from naltrexone, in terms of alcohol and smoking outcomes; it also increased their quit rates more so than in lighter drinkers," Andrea C. King, a psychologist and associate professor in the department of psychiatry at the University of Chicago and first author of the study, was quoted as saying.
  
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  King went on to say strong inter-connections between drinking and smoking for many people could explain their positive results.

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  www.southernillinoisan.com/articles/2007/12/31/breaking - [Cached Version]
  Published on: 12/1/2007    Last Visited: 12/31/2007  

  "Some people can just make the decision and quit," said Andrea King, director of the clinical addictions research lab at the University of Chicago.

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  www.quit-smoking-center.com/news/2006/10/17/news_61.htm - [Cached Version]
  Published on: 10/17/2006    Last Visited: 3/22/2007  

  : Andrea King of the Department of Psychiatry at the University of Chicago and colleagues examined 110 adults who smoked 15 to 40 cigarettes daily and had tried to quit several times, the Chicago Sun-Timesreports.
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  King is conducting a follow-up study that will monitor 324 smokers for one year (Chicago Sun-Times

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  www.jointogether.org/news/research/summaries/2009/naltr - [Cached Version]
  Published on: 3/31/2009    Last Visited: 10/11/2009  

  The effect was less pronounced among lighter drinkers, according to lead researcher Andrea C. King. "Since alcohol drinking may increase urges to smoke and precipitate smoking lapses, it would follow that naltrexone might be beneficial for drinker-smokers," she said, adding that if the findings are confirmed, "use of naltrexone could be expanded to drinkers-smokers who are trying to quit smoking."

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  www.joacp.org/index.php?option=com_content&task=view&id - [Cached Version]
  Published on: 3/21/2009    Last Visited: 6/30/2009  

  "This was a smoking cessation trial," explained Andrea C. King, a psychologist and associate professor in the department of psychiatry at the University of Chicago, and first author of the study. "We examined smokers who did not have any other current addiction - besides tobacco - or mental or medical disorders, which may have confounded the results. The range of alcohol drinking was from abstainer to heavy social drinker."
  
  King and her colleagues examined 78 study participants (43 men, 35 women) drawn from a larger study looking at the effectiveness of naltrexone on smoking cessation. Of the 78, 34 were randomly assigned to receive naltrexone; 44 received a placebo. Dosage at 25 mg daily began three days prior to the quit date, and then continued at 50 mg daily for eight weeks. Drinking and liver enzyme levels were monitored, and all participants received nicotine patches (to ease withdrawal symptoms) and behavioral counseling for up to four weeks following the quit date.
  
  "Naltrexone, at 50 mg oral daily, when added to counseling and patch, significantly decreased heavy drinking rates in smokers enrolled in smoking cessation," said King. "Persons with the heaviest drinking patterns appeared to benefit the most from naltrexone, in terms of alcohol and smoking outcomes; it also increased their quit rates more so than in lighter drinkers."
  
  King noted that that these results are likely based on the strong inter-connections between drinking and smoking for many individuals.
  
  "Both nicotine and alcohol may stimulate brain reward pathways connected to endogenous opioids - meaning the 'endorphins' which are feel-good brain chemicals - as well as dopamine," she said.

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  www.lungchicago.org/site/epage/67694_487.htm - [Cached Version]
  Published on: 10/21/2008    Last Visited: 3/27/2009  

  Disclosure: Jyoti Patel, MD and Andrea King, MD have disclosed no relevant financial relationships.

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  www.principalhealthnews.com/article/healthday/665673 - [Cached Version]
  Published on: 10/1/2006    Last Visited: 10/11/2006  

  "Women have historically not responded as well as men to smoking-cessation treatment, so treatment strategies that show promise with helping them are very interesting," said study author Andrea King, an associate professor of psychiatry at the University of Chicago.
  
  The study authors noted that naltrexone is thought to reduce cigarette and alcohol craving by blocking drug-induced brain signals that convey pleasure.
  
  King and her colleagues studied the potential benefits of the drug among 110 men and women who smoked between 15 and 40 cigarettes a day for an average of 25 years.
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  King and her colleagues evaluated cigarette use, cravings, and treatment side effects.
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  Yet, while the drug didn't appear to influence the men's quit rate, King and her team did find that naltrexone reduced both male and female weight gain commonly experienced by quitters.
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  "This is a treatment option that needs more study, but I am optimistic," said King."And, in the end, it may be that this kind of aggressive treatment somehow addresses both psychological and biological issues that are at play which could account for the complexities of smoking as they specifically relate to women."
  
  King said she's now conducting a study that's three times larger than the first one.She hopes it will help unravel the mechanisms that underlie the drug's affect.
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  SOURCES: Andrea King, Ph.D., associate professor, psychiatry, University of Chicago; Joseph R. Di Franza, M.D., professor, family medicine and community health, University of Massachusetts Medical School, Worcester; October 2006 Nicotine and Tobacco Research

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  nrq.adult-stzzz.com/mla_800_blue_reservoir_assembles_el - [Cached Version]
  Published on: 6/3/2008    Last Visited: 6/3/2008  

  Andrea King, director of the clinical addictions research lab at the University of Chicago, says going cold turkey works for a few, but most need more comprehensive treatment.Miller said he's been waiting for months for a price correction, but it hasn't happened.

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  www.inforesearchlab.com/parentsthatsmoke.chtml - [Cached Version]
  Published on: 4/2/2007    Last Visited: 4/2/2007  

  "Women have historically not responded as well as men to smoking-cessation treatment, so treatment strategies that show promise with helping them are very interesting," said study author Andrea King, an associate professor of psychiatry at the University of Chicago (see above).

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  reak.huge-super-blog.com/intrepit_kart.html - [Cached Version]
  Published on: 5/14/2008    Last Visited: 5/14/2008  

  Andrea King, director of the clinical addictions research lab at the University of Chicago, says going cold turkey works for a few, but most need more comprehensive treatment.Given the federal court's stand on the issue, the latest tack is to declare "personhood" to the fertilized egg, which would be a way of getting around the Supreme Court's reasoning." One way - an approach he honed at the business board - is to show that free trade agreements struck by Latin American governments such as Mexico go beyond matters of trade and form institutional rules that make it hard for governments to slide into a populist agenda that could make the business environment volatile.

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