Dr. Alan G. Hinnebusch

• 
  www.febs-iubmb-2008.org/speakers-chairpersons-laudators - [Cached Version]
  Published on: 6/17/2008    Last Visited: 12/20/2008  

  Alan Hinnebusch Laboratory of Gene Regulation and Development, National Institutes of Health, Bethesda, MA, USA

• 
  meetings.cshl.org/courses/c-yeas07.shtml - [Cached Version]
  Published on: 11/17/2006    Last Visited: 8/7/2007  

  Alan Hinnebusch, NICHD, NIH

• 
  EMBL - About Us - News and Communication -... - [Cached Version]
  Published on: 10/1/2005    Last Visited: 5/14/2006  

  "The high interest in the programme wasnÕt unexpected," says Matthias Hentze, coorganiser alongside Anne Ephrussi [EMBL], Venki Ramakrishnan [LMB] and Alan Hinnebusch [NIH].

• 
  GENETICS -- Genetics Editorial Board - [Cached Version]
  Published on: 11/16/2000    Last Visited: 11/16/2000  

  Alan G. HinnebuschBuilding 6B, Room 413National Institutes of HealthBethesda, MD 20892

• 
  Genome Biology | Research news - [Cached Version]
  Last Visited: 5/16/2009  

  "What's most striking to me, because I'm a yeast geneticist, is that you'd be able to see this effect on feeding behavior," Alan Hinnebusch of the National Institutes of Health, who was not involved in the study, told The Scientist. In yeast, a deficiency of a particular amino acid causes an accumulation of that amino acid's corresponding transfer RNA. This free tRNA
  ...
  Using amino alcohols to reduce amino acid sensing shows that uncharged tRNA is likely the activating ligand, just as in yeast, said Hinnebusch.
  ...
  "It fits perfectly with everything else that's been done in yeast that these alcohol treatments are leading to uncharged tRNA and that's activating GCN2 and eIF-2 phosphorylation," said Hinnebusch. However, he is "a bit skeptical" that Gietzen and her colleagues can be sure that GCN2 is responsible for changes in feeding behavior. The data suggesting that GCN2-null mice do not recognize an amino acid-deficient diet do not reveal "that big of a difference," Hinnebusch said. In addition to measuring the knockouts' response to threonine-devoid food, "it would have been nice to repeat it using some of the alcohols," Hinnebusch said.
  ...
  Alan Hinnebusch

• 
  Members in the News | Genetics Society of America - [Cached Version]
  Published on: 6/12/2008    Last Visited: 8/23/2009  

  Alan G. Hinnebusch, Chief, Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, National Institutes of Health

• 
  Science Calendar - [Cached Version]
  Published on: 9/4/2003    Last Visited: 4/12/2004  

  Alan Hinnebusch, Ph.D.Chief, Laboratory of Gene Regulation and Development

• 
  Stowers Institute for Medical Research - Stowers... - [Cached Version]
  Last Visited: 9/29/2009  

  December 1, 2004 Alan Hinnebusch (National Institutes of Health)

• 
  Translational Control and Non-Coding RNA Meeting - [Cached Version]
  Published on: 5/25/2005    Last Visited: 10/23/2006  

  Alan G. Hinnebusch,National Institute of Child Health and Human Development, Bethesda, USA

• 
  UNIVERSITY OF PITTSBURGH’S INAUGURAL LAUREATE LECTURE... - [Cached Version]
  Published on: 3/9/2004    Last Visited: 3/12/2004  

  · June 9 - Alan G. Hinnebusch, Ph.D., chief of the Laboratory of Gene Regulation and Development at the National Institute of Child Health and Human Development
  ...
  Dr. Hinnebusch uses the yeast Saccharomyces cerevisiae to study the translation of messenger RNA into protein.The transcriptional (information-producing) and translational (protein-producing) machineries of yeast are structurally similar to those found in mammals.Therefore, Dr. Hinnebusch can determine the fundamental mechanisms of gene regulation and protein synthesis in yeast, an easily manipulated model, and translate his findings into information relevant to mammalian cell biology.

Page:  1 2