www.sciencedaily.com/releases/2007/11/071106133113.htm -
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Published on: 1/1/2007
Last Visited: 11/9/2007
"Though just a first step, this work provides a new direction in the search for novel pathways and molecules in the brain to target for the treatment of type 2 diabetes," said Lora Heisler of the University of Cambridge."The challenge now is to come up with drugs that selectively target 5-HT2C receptors safely and effectively."
mCPP has primarily been used in scientific studies of the serotonin pathway and may not itself be appropriate for type 2 diabetes treatment due to its other known effects, Heisler added.
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"Our findings add to emerging evidence that the brain may have important influences on glucose metabolism and insulin action," Heisler added.
While the findings do link serotonin pathways to improved blood sugar tolerance, serotonin supplements would not produce this effect, Heisler noted.