www.eurekalert.org/pub_releases/2008-11/ciot-csd112508. -
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Published on: 11/25/2008
Last Visited: 11/25/2008
The device, known as the Integrated Blood-Barcode Chip, or IBBC, was developed by a group of Caltech researchers led by James R. Heath, the Elizabeth W. Gilloon Professor and professor of chemistry, along with postdoctoral scholar Rong Fan and graduate student Ophir Vermesh, and by Leroy Hood, president of the Institute for Systems Biology in Seattle, Washington.
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"The process is labor intensive, and even if the person doing the testing hurries, the tests will still take a few hours to complete," says Heath.
A kit to test for a single diagnostic protein costs about $50.
"We wanted to dramatically lower the cost of such measurements, by orders of magnitude," he says.
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It's a pretty enabling technology," Heath says.
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"The concentration of this protein increases by about 100,000-fold as a woman goes through the pregnancy cycle, and we wanted to show that we could capture that whole concentration range through a single test," Heath says.
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"As personalized medicine develops, measurements of large panels of protein biomarkers are going to become important, but they are also going to have to be done very cheaply," Heath says.
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