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Published on: 6/25/2008
Last Visited: 6/28/2008
"It was superior to low molecular weight heparin, one of the two most common prophylaxis modalities in the United States," said Dr. William Geerts, a professor of medicine at the University of Toronto, and a member of a team that tested rivaroxaban after hip replacement surgery.
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It already has competition from another anti-clotting drug known as dabigatran, which the pharmaceutical company Boehringer Ingelheim has permission to market in Europe and has approval to start marketing in Canada later this month, Geerts said.
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Both new anti-clotting pills will be an improvement for many people now taking Coumadin, Geerts said.Because of the frequent testing required for Coumadin, many people who are told to take the medication don't follow instructions, he said."This will likely translate to a larger proportion of people who should be on prophylaxis actually getting it," he said.
But the fact that frequent tests aren't required for the new anti-clotting agents is a challenge to physicians, Geerts said.Lab tests are proof-positive that someone is taking their medicine, he said."As physicians, we have to think of new strategies to make sure people are compliant," he added.
More information
Learn more about anticoagulant drugs from the American Heart Association.
SOURCES: William Geerts, M.D., professor, medicine, University of Toronto; Richard C. Becker, M.D., professor, medicine, Duke University Medical Center, Durham, N.C.; June 25, 2008, The Lancet, online; June 26, 2008, New England Journal of Medicine