Anti-cancer compound found in beans, nuts, cereals -
[Cached Version]
Last Visited: 9/15/2005
'Our study suggests the importance of a diet enriched in foods such as beans, nuts and cereals which could help prevent cancer,' said Dr Marco Falasca, of UCL,s Sackler Institute, who reported the finding in the journal Cancer Research.
He and his team discovered that the compound inhibits an enzyme called phosphoinositde 3-kinase which promotes tumour growth.
Scientists have been trying to develop drugs to inhibit the cancer-promoting enzyme but have had difficulty so far.
When the researchers tested inositol pentakisphosphate in mice and cancer cells in the laboratory, it killed the animal tumours and enhanced the effect of drugs used against ovarian and lung cancer cells.
'Our work will now focus on establishing whether the phosphate inhibitor can be developed into an anti-cancer agent for human therapy,' Falasca said in a statement.