Dr. Marco Falasca

Professor Marco Falasca
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7 Okigaki, M., Davis , C., Falasca, M. , Harroch, S., Felsenfeld, D.P., Sheetz, M.P, and Schlessinger, J. (2003) Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.Proc Natl Acad Sci USA , 100:10740-10745.

8 Maffucci, T., Razzini, G., Ingrosso, A. Chen, H., Iacobelli, S., Sciacchitano, S., Quon, M.J. and Falasca, M. (2003) Role of Pleckstrin Homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate-3.
...
9 Maffucci, T., Brancaccio, A., Piccolo, E., Stein, R.C. and Falasca, M. (2003) Insulin induces phosphatidylinositol 3-phosphate formation through TC10 activation . EMBO J ., 22: 4178-89.
...
10 Piccolo, E., Innominato, P.F., Mariggio, M.A., Maffucci, T., Iacobelli, S. and Falasca, M. (2002) The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration.
...
11 Razzini, G., Brancaccio, A., Lemmon, M.A., Guarnieri, S. and Falasca, M. (2000) The role of the Pleckstrin Homology (PH) domain in membrane-targeting and activation of phospholipase Cb1.J.Biol.Chem ., 275 :14873-14881.

12 Razzini, G., Berrie, C.P., Vignati, S., Broggini, M., Mascetta, G., Brancaccio A. and Falasca, M. (2000) Novel functional PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines.FASEB J ., 14 :1179-1187.

13 Falasca, M. , Logan , S.K., Lehto, V.P., Baccante, G., Lemmon M.A. and Schlessinger, J. (1998) Activation of phospholipase Cg1 by PI3-kinase induced PH domain mediated membrane targeting.Embo J., 17 : 414-422.

Marco Falasca Professor in Signal Transduction

Falasca, Professor Marco | Professor Marco Falasca | Prof Marco Falasca
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Falasca, Professor Marco | Professor Marco Falasca | Prof Marco Falasca
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Professor Marco Falasca

Professor of Molecular Pharmacology
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• Okigaki, M., Davis , C., Falasca, M. , Harroch, S., Felsenfeld, D.P., Sheetz, M.P, and Schlessinger, J. (2003) Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.
...
• Maffucci, T., Brancaccio, A., Piccolo, E., Stein, R.C. and Falasca, M. (2003) Insulin induces phosphatidylinositol 3-phosphate formation through TC10 activation. EMBO J., 22: 4178-89.

• Piccolo, E., Innominato, P.F., Mariggio, M.A., Maffucci, T., Iacobelli, S. and Falasca, M. (2002) The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration. Oncogene , 21 :6520-6529.

• Razzini, G., Berrie, C.P., Vignati, S., Broggini, M., Mascetta, G., Brancaccio A. and Falasca, M. (2000) Novel functional PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines. FASEB J., 14:1179-1187.

• Falasca, M. , Logan , S.K., Lehto, V.P., Baccante, G., Lemmon M.A. and Schlessinger, J. (1998) Activation of phospholipase Cg1 by PI3-kinase induced PH domain mediated membrane targeting.

Professor Marco Falasca

Professor of Molecular Pharmacology

Publications since 2001
...
• Okigaki, M., Davis , C., Falasca, M. , Harroch, S., Felsenfeld, D.P., Sheetz, M.P, and Schlessinger, J. (2003) Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration. Proc Natl Acad Sci USA , 100:10740-10745.

• Maffucci, T., Razzini, G., Ingrosso, A. Chen, H., Iacobelli, S., Sciacchitano, S., Quon, M.J. and Falasca, M. (2003) Role of Pleckstrin Homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate-3. Mol. End, 17:1568-1579.

• Maffucci, T., Brancaccio, A., Piccolo, E., Stein, R.C. and Falasca, M. (2003) Insulin induces phosphatidylinositol 3-phosphate formation through TC10 activation . EMBO J, 22:4178-89.

• Piccolo, E., Innominato, P.F., Mariggio, M.A., Maffucci, T., Iacobelli, S. and Falasca, M. (2002) The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration. Oncogene, 21:6520-6529.

Professor Marco Falasca

Professor in Signal Transductions

Centre for Diabetes and Metabolic Medicine
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In 2001 I moved to London and joined Dr Marco Falasca's laboratory at the University College London. We were interested in understanding the mechanisms responsible for insulin resistance. Our attention was focused in particular on signals involving phosphoinositide 3-kinase (PI3K). After one year at the University College London, I started being supported by a Diabetes UK Project Grant to Dr Falasca which lasted three years (Apr 2002-March 2005).

Professor Marco Falasca
...
7 Okigaki, M., Davis , C., Falasca, M. , Harroch, S., Felsenfeld, D.P., Sheetz, M.P, and Schlessinger, J. (2003) Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration. Proc Natl Acad Sci USA , 100:10740-10745.

8 Maffucci, T., Razzini, G., Ingrosso, A. Chen, H., Iacobelli, S., Sciacchitano, S., Quon, M.J. and Falasca, M. (2003) Role of Pleckstrin Homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate-3.
...
9 Maffucci, T., Brancaccio, A., Piccolo, E., Stein, R.C. and Falasca, M. (2003) Insulin induces phosphatidylinositol 3-phosphate formation through TC10 activation . EMBO J ., 22: 4178-89.
...
10 Piccolo, E., Innominato, P.F., Mariggio, M.A., Maffucci, T., Iacobelli, S. and Falasca, M. (2002) The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration.
...
11 Razzini, G., Brancaccio, A., Lemmon, M.A., Guarnieri, S. and Falasca, M. (2000) The role of the Pleckstrin Homology (PH) domain in membrane-targeting and activation of phospholipase Cb1. J. Biol. Chem ., 275 :14873-14881.

12 Razzini, G., Berrie, C.P., Vignati, S., Broggini, M., Mascetta, G., Brancaccio A. and Falasca, M. (2000) Novel functional PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines. FASEB J ., 14 :1179-1187.

13 Falasca, M. , Logan , S.K., Lehto, V.P., Baccante, G., Lemmon M.A. and Schlessinger, J. (1998) Activation of phospholipase Cg1 by PI3-kinase induced PH domain mediated membrane targeting. Embo J., 17 : 414-422.