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Dr. John A. Collins

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Dalhousie University
Halifax, Nova Scotia, Canada
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    www.kdbc.com/news/national/8364057.html - [Cached Version]
    Published on: 7/6/2007    Last Visited: 7/6/2007  

    In an editorial accompanying the study, John A. Collins, M.D., a physician at McMaster University in Hamilton, Ontario and Dalhousie University, Halifax, Nova Scotia, Canada, puts the results in perspective: "he results suggest that for every nine women who are 35 to 41 years of age who plan three cycles of IVF or IVF and intracytoplasmic sperm injection, there will be one more live birth if pre-implantation genetic diagnosis for [abnormalities] is not performed."

    In an e-mail interview, Collins tells WebMD that the new study results are "convincing most people in the field that PGS has no value in screening infertile women over 35 undergoing IVF."

    In his editorial, Collins advises that the preimplantation screening not be done solely due to a woman's age.

    Are you considering IVF as part of your infertility treatment?Find others like you on WebMD's Infertility Treatments Support Group message board.

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    www.medpagetoday.com/PublicHealthPolicy/Genetics/tb/608 - [Cached Version]
    Published on: 7/4/2007    Last Visited: 7/5/2007  

    In an accompanying editorial, John Collins, M.D., of Dalhousie University in Halifax, Nova Scotia, said that for every nine women who use three cycles of IVF, there would be one more live birth if genetic screening had not been used, on the basis of data from the study.

    Because about 8% of pregnancies established by IVF are lost after 12 weeks, the use of on-going pregnancy at 12 weeks as the primary outcome "in my opinion is a design flaw," Dr. Collins said.

    Nevertheless, he added, live births were analyzed as a secondary outcome and the results are sufficiently strong to rule out genetic screening for chromosomal abnormalities "solely because of advanced maternal age."

    For other indications -- such as recurrent unexplained miscarriage and recurrent implantation failure -- the issue is still up in the air, he said, but the procedure should only be used in clinical trials designed to answer the question.

    The research was supported by the Netherlands Organization for Health Research and Development.The authors reported no relevant financial links.

    Dr. Collins reports financial links with Organon Canada, Ferring, NV Organon, Procter & Gamble, BioSymposia (previously Serono Symposia International), and Institut Biochimique.

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    www.lupronexposed.com/lpexp/articles4.htm - [Cached Version]
    Published on: 2/1/2004    Last Visited: 11/20/2008  

    Last spring I received a letter from John Collins, MD, professor emeritus of obstetrics and gynecology at McMaster University in Ontario, who was an author of the Cochrane review and is considered an experienced evaluator of ovarian cancer studies. "The risk is not one that would be considered proven," he wrote, "and the subject does not seem to have had a high priority for further research in the last few years."

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    www.anabaptistethics.org/article.php?id=6418 - [Cached Version]
    Published on: 7/4/2007    Last Visited: 11/23/2007  

    "Given these findings, PGS for aneuploidy screening should not be performed solely because of advanced maternal age," comments John Collins of Dalhousie University in Halifax, Canada.

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    www.visembryo.com/baby/NewsArchive18.html - [Cached Version]
    Last Visited: 11/21/2007  

    John Collins, M.D., of Dalhousie University in Halifax, Nova Scotia, said that for every nine women who use three cycles of IVF, there would be one more live birth if genetic screening had not been used, on the basis of data from the study.Because about 8% of pregnancies established by IVF are lost after 12 weeks, the use of on-going pregnancy at 12 weeks as the primary outcome "in my opinion is a design flaw," Dr. Collins said.Nevertheless, he added, live births were analyzed as a secondary outcome and the results are sufficiently strong to rule out genetic screening for chromosomal abnormalities "solely because of advanced maternal age."Published July 5 issue of the New England Journal of Medicine.

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    www.seronosymposia.org/en/ReproductiveHealth/Symposia/B - [Cached Version]
    Published on: 4/11/2007    Last Visited: 4/11/2007  

    John CollinsMcMaster University

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    www2.netanalysis.org/newsarticles.pl?m=2&r=VnlbCpwn5uVg - [Cached Version]
    Published on: 5/25/2007    Last Visited: 5/26/2007  

    Dr. John Collins, of McMaster University in Hamilton, said that while in vitro "isn't a huge factor in the big picture … it's one factor that you could possibly do something about, because so many of the other factors are social and genetic."

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    www.biosymposia.org/content16446.html - [Cached Version]
    Published on: 3/5/2007    Last Visited: 3/5/2007  

    John Collins M.D., FRCSC, FRCOG, FACOG

    Professor

    McMaster University

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    'Couples need more help conceiving' - Yahoo! UK &... - [Cached Version]
    Published on: 2/24/2005    Last Visited: 2/24/2005  

    The research carried out by Professor John Collins of McMaster University in Ontario, Canada, also found that 85% of people will never seek any help for their conception problems.

  • View Online Source
    94% of Couples Who Experience Problems Having a Baby... - [Cached Version]
    Published on: 2/23/2005    Last Visited: 2/23/2005  

    Professor John A. Collins, McMaster University, Hamilton, Ontario.Global Epidemiological Conception Difficulties Model (ii). 'Barriers to Assisted Conception Treatment' - LightSpeed Research, June 2004

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