Dr. Jenny Chee Chang

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  www.biohouston.com/en/cev/202 - [Cached Version]
  Published on: 10/2/2009    Last Visited: 10/7/2009  

  October's Breakfast Forum will feature Dr. Jenny Chang, Dan L Duncan Professor of Medicine, and Medical Director of the Smith Breast Center at Baylor College of Medicine.
  
  Dr. Chang obtained her medical degree at
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  Dr. Chang is also working on a project with the Breast Cancer Research Foundation.

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  www.eurekalert.org/pub_releases/2009-08/bcom-gsf072909. - [Cached Version]
  Published on: 8/3/2009    Last Visited: 8/3/2009  

  These patterns resemble expression patterns more closely associated with cells with a mesenchymal (a form of connective tissue) phenotype (or appearance)," said Dr. Jenny Chang (http://www.bcm.edu/breastcenter/?PMID=10728), medical director of the Sue and Lester Smith Breast Center (http://www.bcm.edu/cancercenter/) at BCM and a professor of medicine. Chang is a senior author of the paper along with Drs.
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  They found that gene expression patterns in these chemoresistant cells represented a tumor-initiating gene signature, which was not only more easily detectable in a newly-defined breast cancer subtype called "claudin-low", but also enriched in human breast tumors after they had been treated with anti-cancer drugs that target the signals of hormones, said Chang. They also found that genes associated with the mesenchymal cell phenotype were increased in breast tumors after hormone treatment.
  
  "This study supports a growing body of evidence that there is a particular subpopulation of cells in breast cancer that may be responsible for disease recurrence, resistance to treatment, and perhaps metastasis (cancer spread)," said Chang.
  
  In the future, she said, the group will be looking at ways to use the gene signature they have identified to develop drugs that can combine with conventional therapy to eradicate all populations of cells within tumors.

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  www.eurekalert.org/pub_releases/2008-04/bcom-gtt042408. - [Cached Version]
  Published on: 4/24/2008    Last Visited: 4/30/2008  

  "The tumor shrank dramatically," said Dr. Jenny Chang, associate professor of medicine at BCM and medical director of the BCM Breast Care Cancer Center.

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  newinoil.faistonblog.com/2008/05/06/created-page-with-h - [Cached Version]
  Published on: 1/1/2008    Last Visited: 5/20/2008  

  The results from this study are exciting, said Jenny Chang, MD, Medical Director, Breast Care Center, Associate Professor of Medicine, Baylor College of Medicine, Houston, Texas and lead investigator on this study.

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  news.pharmacyonlineshop.com/newsid=104573 - [Cached Version]
  Published on: 12/13/2007    Last Visited: 4/18/2008  

  "The results from this study are exciting," said Jenny Chang, M.D., Medical Director, Breast Care Center, Associate Professor of Medicine, Baylor College of Medicine, Houston, Texas and lead investigator on this study.
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  Jenny C Chang, Xiaoxian Li, Chad Creighton, et al. 6th European Breast Cancer Conference 2008; Oral presentation: abstract# 204

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  www.click2houston.com/health/19854969/detail.html - [Cached Version]
  Published on: 6/25/2009    Last Visited: 7/4/2009  

  "This drug, which has few side affects -- no nausea, no vomiting, no hair loss -- can be given as a tablet to a patient," said Dr. Jenny Chang with the Baylor College of Medicine.
  
  Radiation and chemotherapy are known to be very painful, physically and emotionally, for cancer patients. Chang said this new drug would result in just the opposite.
  
  "The hope is in the near future, in the next few years, we may actually be able to replace chemotherapy with targeted therapy directed against the gene that causes the cancer to grow," said Chang.
  
  Chang suggested to contact your doctor to find out about clinical trials using this drug.

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  www.cbc.ca/health/story/2008/04/29/breastcancer-roots.h - [Cached Version]
  Published on: 4/30/2008    Last Visited: 4/30/2008  

  "The tumor shrank dramatically," said Dr. Jenny Chang, associate professor of medicine at the Baylor College of Medicine and medical director of the Lester and Sue Smith Breast Care Cancer Center, in a release.

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  www.clinicalbreastcancer.com/publication/genentech_slid - [Cached Version]
  Published on: 9/1/2006    Last Visited: 11/26/2007  

  Jenny Chang, MD
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  Jenny Chang, MDResearch Funding , Genentech BioOncology, GlaxoSmithKline

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  www.eurekalert.org/pub_releases/2008-04/jotn-ohi042408. - [Cached Version]
  Published on: 4/24/2008    Last Visited: 4/30/2008  

  To find out how the CD44+/CD24-/low cells respond to cytotoxic chemotherapy, Jenny Chang, M.D., from the Baylor College of Medicine in Houston and colleagues compared breast cancer biopsy samples taken from patients before and after standard chemotherapy or lapatinib therapy.
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  Contact: Jenny Chang, jcchang@bcm.tmc.edu, (713) 798-1034

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  www.newsmax.com/health/chemo_fails_stem_cells/2008/04/3 - [Cached Version]
  Published on: 1/1/2008    Last Visited: 5/1/2008  

  "The tumor shrank dramatically," said Jenny Chang, associate professor of medicine and medical director of the BCM Breast Care Cancer Center.

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