Dr. C. Thomas Caskey This is Me

Education

 View all 390 references Web References

1. 1. Board of Directors

   www.envivopharma.com/template/ - [Cached]

   Published on: 6/23/2008   Last Visited: 6/23/2008

   C. Thomas Caskey, M.D. (Brown Foundation Institute of Molecular Medicine - Univ. of Texas)
   
   C. Thomas Caskey, M.D., F.A.C.P., is Director and Chief Executive Officer-Elect and Chief Operating Officer of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), at the University of Texas Health Science Center at Houston.Dr. Caskey was founding director of Houston-based Cogene Biotech Ventures and Cogene Ventures, venture capital funds supporting early-stage biotechnology and life sciences companies.The fund, founded in March 2000, invested in companies that utilize genome technology to enable drug discovery in high growth therapeutic specialties such as cancer, neurology and the metabolic diseases of obesity and diabetes.Dr. Caskey has received numerous academic and industry-related honors.He is a member of the National Academy of Sciences and the Institute of Medicine.He has served as president of American Society of Human Genetics, the Human Genome Organization and The Academy of Medicine, Engineering and Science of Texas (TAMEST).He previously served as senior vice president for human genetics and vaccines discovery at Merck Research Laboratories from 1994 to 2000 and as president of the Merck Genome Research Institute from 1998 to 2000.He received the Distinguished Texas Geneticist Award from the Texas Genetics Society in 1998 and serves on Texas Governor Rick Perry's Council on Science and Biotechnology, which makes funding recommendations for the $200 million Texas Emerging Technology Fund.Dr. Caskey earned his medical degree from Duke University School of Medicine and his undergraduate degree from the University of South Carolina.He is Board certified in Internal Medicine, Clinical Genetics, Metabolic Diseases and Molecular Diagnostics.

2. 2. Etubics Corporation

   www.etubics.com/tc.html - [Cached]

   Published on: 11/16/2007   Last Visited: 11/16/2007

   C. Thomas CaskeyEtubics Corporation
   ...
   C. Thomas Caskey, M.D., F.A.C.P., is Director and Chief Executive Officer of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) and Executive Vice-President of Molecular Medicine and Genetics at the University of Texas Health Science Center at Houston.He has served on the Company's Board of Directors since 2007.
   
   Dr. Caskey was Chief Executive Officer and President of Cogene Biogene Ventures and Cogene Ventures, venture capital funds designed to support early-stage biotechnology and life sciences companies using genome technology for drug discovery.He served as Senior Vice-President, Human Genetics and Vaccines Discovery at Merck Research Laboratories, West Point, PA and as President of the Merck Genome Research Institute.He was Chairman of the board of Lexicon as the company transformed itself from a mouse discovery company to a Nasdaq listed pharmaceutical corporation.
   
   Dr. Caskey is a graduate of the University of South Carolina (Phi Beta Kappa) and Duke Medical School (Alpha Omega Alpha).He has received numerous academic and industry-related honors.His genetic research documented the Universality of the Genetic Code, discovered the mechanism of peptide chain termination, identified the genetic basis of 10 major heritable diseases, opened the understanding of triplet repeat diseases (Fragile X, myotonic dystrophy and others), developed the STR method of personal identification (now used worldwide) for forensic studies, and developed a viral vector vaccine for HIV.He is Past President of the American Society of Human Genetics and the Human Genome Organization.He served as Chair of the Advisory Panel on Forensic Uses of DNA Tests, U.S. Congress Office of Technology Assessment, 1989-1990.He served as President of the Academy of Medicine, Engineering and Science of Texas from 2004-2006.Dr. Caskey currently serves on the Governor's Committee of 17, which has oversight of the Texas 200 million Emerging Technology Fund.He is a member of the National Academy of Sciences and the Institute of Medicine.

3. 3. Genome Canada - Board of Directors

   www.genomecanada.ca/en/about/g - [Cached]

   Published on: 7/13/2008   Last Visited: 7/13/2008

   C. Thomas Caskey
   ...
   C. Thomas CaskeyDirector and Chief Executive OfficerThe Brown Foundation Institute of Molecular Medicine and Genetics
   ...
   Dr. Caskey attended the University of South Carolina (1956-58) and Duke University Medical School (1958-63).As a medical student he was a Biochemical Fellow (1961-62) with James B. Wyngarden, a pioneer in the study of the biochemical basis of the metabolic disease, gout.After receiving his M.D. degree, Dr. Caskey remained at Duke as an intern and resident in the Department of Medicine (1963-65).His first resarch paper with Dr. H. Estes was on the "ST segment of the EKG in myocardial injury".
   
   Dr. Caskey then went to the National Institutes of Health (1965-71) where he was a Research Associate with Nobel Laureate Marshall Nirenberg.
   ...
   Dr. Caskey then became Senior Investigator in the Laboratory of Biochemical Genetics (1967-70) and Head of the Section of Medical Genetics at NHLBI (1970-71).As an independent investigator he discovered the mechanism of code punctuation (stop) to be translated by proteins, not tRNA.
   
   Dr. Caskey joined Baylor College of Medicine in 1971 where he served as Chief of the Section of Medical Genetics (1971-85) and Professor of Medicine and Biochemistry (1971-94).He discovered 11 genetic disease genes during this period.From 1976 to 1994 Dr. Caskey was a Howard Hughes Medical Institute Investigator.Most importantly, he discovered the "triplet repeat" diseases (fragile X and myotonic dystrophy) and the molecular basis of "disease anticipation" (triplet expansion generation to generation).His patent for automation of forensic science use of repeat sequences enabled ABI to use the method worldwide.During a sabbatical leave (1979-80) Dr. Caskey was a Faculty Scholar at the Cambridge University Medical Research Council Unit with Nobel Laureate Sydney Brenner.This training enabled him to transform the Department at Baylor for the genomic era; he served as the first Director of the NIH Genome Center at Baylor College of Medicine.He also served as Director of the Medical Scientist Training Program, Professor of Cell Biology, as the Henry and Emma Meyer Chair in Molecular Genetics, Professor of Molecular Genetics, and Chair of the Department of Molecular and Human Genetics, at Baylor.
   
   Dr. Caskey left academia in 1994 to assume the position of Senior Vice President for Research at Merck Research Laboratories, West Point, Pennsylvania, and Trustee and President of the Merck Genome Research Institute.The development of the adenoviral vector HIV vaccine was achieved by a research team under Dr. Caskey's direction.
   
   Dr. Caskey returned to Houston in 2000 and became Founding Director and Chief Executive Officer of Cogene Biotech Ventures and Cogene Ventures, venture capital funds designed to support early-stage biotechnology and life sciences companies using genome technology for drug discovery.
   
   In 2006 Dr. Caskey was appointed Chief Operating Officer and Director-/CEO-Elect of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases and Executive Vice President of Molecular Medicine and Genetics at the University of Texas Health Science Center-Houston.In 2007 Dr. Caskey was named Director and Chief Executive Officer of the Brown Foundation Institute of Molecular Medicine and the George & Cynthia Mitchell Distinguished Chair in the Neurosciences.
   
   He has served as Chair of the Board of Lexicon Genetics, a Woodlands, Texas biotechnology company, as the company transformed itself from a mouse discovery company to a Nasdaq-listed pharmaceutical corporation.Other recent past Board memberships include the Muscular Dystrophy Association, the Foundation for Biomedical Research, Motorola BioChips, Athersys, Kodiak Technologies, Vical, Xeotron, Etubics, BioHouston, MDS, and Argolyn.He served as Special Advisor to the World Health Organization Hereditary Diseases Program and a member of the World Health Organization's Expert Advisory Panel on Human Genetics.He was President of The Human Genome Organization (HUGO) between 1993-1996.Presently, Dr. Caskey serves on the Boards of Essex Woodlands Health Ventures, Luminex, Odyssey Thera, En Vivo, Metabolon, Genome Canada, Laboratory Corporation of America, as well as serving as a member of the Science Review Panel for the US Food and Drug Administration.He is Editor of the Annual Review of Medicine.
   
   Dr. Caskey is a member of the Academy of Medicine, Engineering and Science of Texas (President of TAMEST 2004-05), a member of the National Academy of Sciences, and the Institute of Medicine.He serves on Texas Governor Rick Perry's Advisory Committee which provides oversight for the Texas Emerging Technology Fund.He is a Fellow of the American Academy of Microbiology, American Association for the Advancement of Science, American College of Medical Genetics, American College of Physicians, and the Royal Society of Medicine.He is a member of the American Society of Human Genetics (President 1990-1991), American Academy of Pharmaceutical Physicians, American Society for Biochemistry and Molecular Biology, American Society for Cell Biology, American Society for Clinical Investigation, American Society of Gene Therapy, American Society for Microbiology, American Medical Association, Association of American Physicians, and the Society for Inherited Metabolic Disorders.
   
   Dr. Caskey's most recent award (2007) was the Medical Statesman Award from the Health Access Foundation.Other awards include: Borden Research Award, Distinguished Alumnus Award (Duke University Medical School), Wadsworth Award (New York State Department of Health), Leadership Award (Muscular Dystrophy Association), Giovanni Lorenzini Foundation Prize for Basic Biomedical Research, Lucy Wortham James Basic Research Award (Society of Surgical Oncology), Norberto Montalbetti Milan Award, Texas 20 Award (Texas Monthly magazine), Corielle Award, Distinguished Texas Geneticist Award, and Courage in DNA Award from the Department of Justice.
   
   Back
   
   C. Thomas Caskey