Dr. Brian M. Casey M.D.

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  next.thyroid.org/professionals/publications/news/04_04_ - [Cached Version]
  Published on: 4/27/2004    Last Visited: 8/6/2008  

  Preterm birth, as Brian M. Casey, MD, Associate Professor of Obstetrics and Gynecology at the University of Texas Southwestern Medical Center at Dallas, pointed out, is the most common recognized cause of neuropsychological dysfunction in children.After reviewing the association of subclinical hypothyroidism with preterm birth, he concluded that "Prematurity may explain some of the neurodevelopmental abnormalities associated with maternal thyroid insufficiency."

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  AP Wire | 05/10/2004 | Pregnancy thryroid testing... - [Cached Version]
  Published on: 5/10/2004    Last Visited: 5/11/2004  

  Prematurity might explain the lower-IQ link, says lead researcher Dr. Brian Casey, who presented his results at last month's thyroid meeting.

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  CBS News | Thyroid Problems And Pregnancy | May 10,... - [Cached Version]
  Published on: 5/10/2004    Last Visited: 5/11/2004  

  Dr. Brian Casey,University of Texas Southwestern Medical Center
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  Prematurity might explain the lower-IQ link, says lead researcher Dr. Brian Casey, who presented his results at last month's thyroid meeting.

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  ChuMD.com, Simple Newborn Test Still The Best - [Cached Version]
  Published on: 1/12/2001    Last Visited: 5/29/2001  

  The test , named for Dr. Virginia Apgar , the anesthesiologist who developed it in 1952 , predicts survivability better than a new , high-tech test of umbilical cord blood , report researchers led by Dr. Brian M. Casey , assistant professor of obstetrics and gynecology at the University of Texas Southwestern Medical Center in Dallas in the Feb.
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  The study was done because , in medicine , if something has been around for nearly 50 years , people assume that it will not work as well as the latest technology , Casey says.
  
  A newborn baby's Apgar score usually is based on observations made one minute and again at five minutes after birth.A doctor or nurse looks at five things : heart rate , respiratory effort , muscle tone , motor reaction and color , an indication of the amount of oxygen reaching the skin.Each gets a score from 0 to 2. A total score of 7 or higher means that the baby's condition is good to excellent.A score of 3 or less indicates serious trouble and a high risk of death.
  
  Casey and his colleagues looked at predictions based on the Apgar score and umbilical cord blood tests on more than 150 , 000 babies born between January 1988 and December 1998.
  
  Nearly a quarter of the babies with Apgar scores of 3 or under five minutes after birth died , compared with only 2 babies of every 10 , 000 with Apgar scores of 7 or higher , the researchers say.The test predicted survival better than the blood analysis , which measures acidity , carbon dioxide levels and oxygen levels.Newborns scoring 3 or under on the Apgar test were eight times likelier to die than those with corresponding danger signs on the blood tests.
  
  There have been rumblings in the medical literature that the Apgar score has served its purpose and should be pensioned off , Casey says.
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  But Casey notes the Apgar score measures only survivability.It has been controversial because some people were using it for things it was not intended to do , such as looking for neurological problems , he says.
  
  And he doesn't write off the cord blood test.It offers more detailed information in regards to metabolic rates , Casey says.

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  DailyBulletin.com - More News - [Cached Version]
  Published on: 5/10/2004    Last Visited: 5/11/2004  

  Prematurity might explain the lower-IQ link, says lead researcher Dr. Brian Casey, who presented his results at last month's thyroid meeting.

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  Devereux: Creating Communities of Hope Since 1912 - [Cached Version]
  Published on: 5/24/2004    Last Visited: 5/25/2004  

  Prematurity might explain the lower-IQ link, says lead researcher Brian Casey, who presented his results at last month's thyroid meeting.

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  Low thyroid poses pregnancy risks - 05/11/04 - [Cached Version]
  Last Visited: 5/11/2004  

  Prematurity might explain the lower-IQ link, researcher Dr. Brian Casey said.

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  NurseZone - Relationships - Family - Archive - [Cached Version]
  Published on: 11/27/2000    Last Visited: 3/13/2001  

  The test, named for Dr. Virginia Apgar, the anesthesiologist who developed it in 1952, predicts survivability better than a new, high-tech test of umbilical cord blood, report researchers led by Dr. Brian M. Casey, assistant professor of obstetrics and gynecology at the University of Texas Southwestern Medical Center in Dallas in the Feb. 15 issue of the New England Journal of Medicine.
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  The study was done because, "in medicine, if something has been around for nearly 50 years, people assume that it will not work as well as the latest technology," Casey says.
  
  A newborn baby's Apgar score usually is based on observations made one minute and again at five minutes after birth.A doctor or nurse looks at five things: heart rate, respiratory effort, muscle tone, motor reaction and color, an indication of the amount of oxygen reaching the skin.Each gets a score from 0 to 2.A total score of 7 or higher means that the baby's condition is good to excellent.A score of 3 or less indicates serious trouble and a high risk of death.
  
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  Casey and his colleagues looked at predictions based on the Apgar score and umbilical cord blood tests on more than 150,000 babies born between January 1988 and December 1998.
  
  Nearly a quarter of the babies with Apgar scores of 3 or under five minutes after birth died, compared with only 2 babies of every 10,000 with Apgar scores of 7 or higher, the researchers say.The test predicted survival better than the blood analysis, which measures acidity, carbon dioxide levels and oxygen levels.Newborns scoring 3 or under on the Apgar test were eight times likelier to die than those with corresponding danger signs on the blood tests.
  
  "There have been rumblings in the medical literature that the Apgar score has served its purpose and should be pensioned off," Casey says."Our study indicates that is not the case.It is doing what it was initially intended to do, and doing it better than the cord blood test."
  
  But Casey notes the Apgar score measures only survivability."It has been controversial because some people were using it for things it was not intended to do, such as looking for neurological problems," he says.
  
  And he doesn't write off the cord blood test."It offers more detailed information in regards to metabolic rates," Casey says."Doing both the cord blood test and the Apgar test together does improve the ability to predict survival.We do both."

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  Old System Still Good For Assessing Newborns... - [Cached Version]
  Published on: 2/1/2001    Last Visited: 2/5/2002  

  The Apgar scoring system--a way to judge an infant's health and need for medical attention shortly after birth, first proposed in 1952 by obstetrical anesthesiologist Virginia Apgar--is still a good guide for predicting infant survival in the first month after birth, says Brian M. Casey, MD, assistant professor of obstetrics and gynecology at the University of Texas Southwestern Medical Center.
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  Casey is lead author of a study in the February 15 issue of the New England Journal of Medicine (NEJM).
  
  Babies are given a score of 0, 1, or 2 for each of five characteristics--heart rate, breathing, muscle tone, color, and "reflex irritability" (a measure of innate reflexes shown in facial expressions).Scores of 7 or higher (the maximum score is 10) are considered good to excellent.Scores are recorded at one minute after birth, and again at the five-minute mark.
  
  "The score at one minute is really intended for physicians to be able to accurately identify babies that are in need of help or resuscitation.And then the five-minute score is a good indicator of how we're doing in our resuscitation, and also a better indicator of what the survival of the baby is going to be," Casey explains.
  
  Casey and his fellow researchers compared both the Apgar scores and the scores from a more advanced test measuring umbilical artery blood pH with the mortality rates for nearly 152,000 infants born at the same hospital over an 11-year period.
  
  "The Apgar score is as good as it was almost 50 years ago at identifying babies that are in need of help and identifying babies that are at risk for dying in the first month after they're born," Casey says.
  
  While some have called Apgar scores "antiquated," the study from Casey's group shows the method is still valid for the purpose it was intended, writes Lu-Ann Papile, MD, of the University of New Mexico School of Medicine in an editorial also appearing in the February 15 issue of NEJM.
  
  One criticism of the Apgar score is that it does not gauge an infant's potential for future neurological problems due to lack of oxygen at birth--but it was never intended to serve this purpose, Papile notes.
  
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  "Around 1950, about 2%, or 20 in 1,000 babies who were born alive died within the first month of life, and nowadays, only about 5 in 1,000 babies that are born alive die within the first month," Casey says.

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  Rounds & Lectures * New York City's St.... - [Cached Version]
  Published on: 5/18/2009    Last Visited: 5/18/2009  

  9:00: Brian M. Casey, MD Associate Professor Department of Obstetrics and Gynecology University of Texas Southwestern Medical School

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