Dr. Alina V. Brenner

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  A bad time of the month - [Cached Version]
  Published on: 8/22/2004    Last Visited: 8/22/2004  

  The paper's lead author, NCI epidemiologist Alina V Brenner, is the first to offer a caveat: The findings could be the result of chance.
  
  But separate studies in Britain and Norway have identified a similar co-relation between birth season and risk of brain tumors in children, with a statistical ‘‘excess" of births in winter and a ‘‘deficit" in summer.If the association turns out to be real, Brenner said, it suggests that exposures early in a child's development - at any point from conception to the first few months after birth - could have a hand in the genesis of the disease.

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  Allergies may protect against brain cancer: study - [Cached Version]
  Published on: 8/13/2001    Last Visited: 5/17/2002  

  To see whether autoimmune disease and allergies offer any protection against brain cancer, a team led by Dr. Alina V. Brenner of the National Cancer Institute in Bethesda, Maryland, compared 782 people hospitalized with a brain tumor with a "control" group of 799 patients hospitalized for other causes.
  
  Having allergies or an autoimmune illness reduced the risk of some, but not all, brain tumors, Brenner and her colleagues report in the International Journal of Cancer.The risk of a type of brain tumor called glioma was reduced 33% in people with a history of allergies and 51% in those with an autoimmune disease.The risk was lowest in people who had both allergies and autoimmune disease.
  
  The risk of another type of brain cancer, meningioma, was lower in people with an autoimmune disease, but not in those with allergies, the report indicates.
  
  The finding of a reduced risk of glioma in people with a history of allergies or autoimmune diseases is in agreement with several previous studies, according to Brenner."Given that so little is known about factors that influence the risk of glioma, this finding is particularly exciting," she told Reuters Health.
  
  She cautioned, however, "At this point, it is premature to draw definite conclusions about the underlying basis of the association."
  
  There are several possible explanations for the apparent reduction in risk, according to Brenner.Immune factors that are involved in or predispose people to autoimmunity or allergies might play a role, she said.It is also possible that medications used to treat these conditions could offer some protection.Other factors including some that are not involved with the immune system may also affect the risk, she noted.
  
  "Clearly, this is a promising area of research that warrants further investigation," Brenner said.
  
  International Journal of Cancer 2002;99:252-259.
  
  Copyright 2000-2001 Reuters Limited.All rights reserved.Republication or redistribution of Reuters content is expressly prohibited without the prior written consent of Reuters.Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

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  Birth Month May Influence Brain Cancer Risk -... - [Cached Version]
  Published on: 8/16/2004    Last Visited: 8/17/2004  

  For one, it's possible that the associations were simply due to chance, says lead author Dr. Alina V. Brenner of the National Cancer Institute, Bethesda, Maryland.
  
  The aim of the study, the researcher explained, was to unearth possible new clues about the causes of brain tumors -- something that scientists currently know little about.
  
  If the association between birth season and brain cancer risk is real, then researchers could investigate the factors that operate during pregnancy and early infancy and vary by season.Some "candidate" factors, according to Brenner and her colleagues, include infections, maternal diet, environmental toxins and hormonal influences during pregnancy.
  
  But, Brenner noted, too little is known to tell which, if any, of these factors could be at work.

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  Birth Month link to Diseases [Archive] - Friends... - [Cached Version]
  Published on: 8/20/2004    Last Visited: 1/18/2007  

  The paper's lead author, NCI epidemiologist Alina V. Brenner, is the first to offer a caveat: The findings could be the result of chance.
  
  But separate studies in Britain and Norway have identified a similar correlation between birth season and risk of brain tumors in children, with a statistical "excess" of births in winter and a "deficit" in summer.
  
  If the association turns out to be real, Brenner said, it suggests that exposures early in a child's development -- at any point from conception to the first few months after birth -- could have a hand in the genesis of the disease.

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  Born in August? You're less likely to get brain cancer... - [Cached Version]
  Published on: 8/21/2004    Last Visited: 8/21/2004  

  The paper's lead author, NCI epidemiologist Alina Brenner, is the first to offer a caveat: The findings could be the result of chance.
  
  But separate studies in Britain and Norway have identified a similar correlation between birth season and risk of brain tumours in children, with a statistical 'excess' of births in winter and a 'deficit' in summer.
  
  If the association turns out to be real, Ms Brenner said, it suggests that exposures early in a child's development - at any point from conception to the first few months after birth - could have a hand in the genesis of the disease.

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  Calendar Could Offer Clues About Disease - [Cached Version]
  Published on: 8/20/2004    Last Visited: 8/13/2008  

  The paper's lead author, NCI epidemiologist Alina V. Brenner, says, though, that the findings could be the result of chance.
  
  But separate studies in Britain and Norway have identified a similar correlation between birth season and risk of brain tumors in children, with a statistical "excess" of births in winter and a "deficit" in summer.
  
  If the association turns out to be real, Brenner said, it suggests that exposures early in a child's development -- at any point from conception to the first few months after birth -- could have a hand in the genesis of the disease.

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  Cancer - Allergies May Protect Against Brain Cancer:... - [Cached Version]
  Published on: 12/12/2001    Last Visited: 9/8/2002  

  To see whether autoimmune disease and allergies offer any protection against brain cancer, a team led by Dr. Alina V. Brenner of the National Cancer Institute (news - web sites) in Bethesda, Maryland, compared 782 people hospitalized with a brain tumor with a "control" group of 799 patients hospitalized for other causes.
  
  Having allergies or an autoimmune illness reduced the risk of some, but not all, brain tumors, Brenner and her colleagues report in the International Journal of Cancer.The risk of a type of brain tumor called glioma was reduced 33% in people with a history of allergies and 51% in those with an autoimmune disease.The risk was lowest in people who had both allergies and autoimmune disease.
  
  The risk of another type of brain cancer, meningioma, was lower in people with an autoimmune disease, but not in those with allergies, the report indicates.
  
  The finding of a reduced risk of glioma in people with a history of allergies or autoimmune diseases is in agreement with several previous studies, according to Brenner."Given that so little is known about factors that influence the risk of glioma, this finding is particularly exciting," she told Reuters Health.
  
  She cautioned, however, "At this point, it is premature to draw definite conclusions about the underlying basis of the association."
  
  There are several possible explanations for the apparent reduction in risk, according to Brenner.Immune factors that are involved in or predispose people to autoimmunity or allergies might play a role, she said.It is also possible that medications used to treat these conditions could offer some protection.Other factors including some that are not involved with the immune system may also affect the risk, she noted.
  
  "Clearly, this is a promising area of research that warrants further investigation," Brenner said.
  
  SOURCE:
  
  International Journal of Cancer 2002;99:252-259.
  
  "Reuters content is the intellectual property of Reuters Limited.Any copying, republication or redistribution of Reuters content, including by caching, framing or similar means, is expressly prohibited without the prior written consent of Reuters.

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  Duluth News Tribune | 08/21/2004 | 'What's your sign?'... - [Cached Version]
  Published on: 8/21/2004    Last Visited: 8/21/2004  

  The paper's lead author, cancer institute epidemiologist Alina Brenner, is the first to offer a caveat: The findings could be the result of chance.
  
  But separate studies in Britain and Norway have identified a similar correlation between birth season and risk of brain tumors in children, with a statistical "excess" of births in winter and a "deficit" in summer.
  
  If the association turns out to be real, Brenner said, it suggests that exposures early in a child's development -- at any point from conception to the first few months after birth -- could have a hand in the genesis of the disease.

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  Ed Gorman & Friends: August 2004 Archives - [Cached Version]
  Published on: 8/1/2004    Last Visited: 8/4/2005  

  For one, it's possible that the associations were simply due to chance, lead author Dr. Alina V. Brenner of the National Cancer Institute, Bethesda, Maryland, told Reuters Health.
  
  The aim of the study, the researcher explained, was to unearth possible new clues about the causes of brain tumors -- something that scientists currently know little about. If the association between birth season and brain cancer risk is real, then researchers could investigate the factors that operate during pregnancy and early infancy and vary by season. Some "candidate" factors, according to Brenner and her colleagues, include infections, maternal diet, environmental toxins and hormonal influences during pregnancy.
  
  But, Brenner noted, too little is known to tell which, if any, of these factors could be at work.

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  Epilepsy Fdn.-Epilepsy USA Online Archive - [Cached Version]
  Published on: 11/11/2004    Last Visited: 3/22/2006  

  A study led by Alina Brenner, M.D., Ph.D., of the National Cancer Institute showed that babies born in January and February might be more at risk of developing brain cancer, epilepsy, diseases affecting the nervous system, schizophrenia and bipolar disorder.

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