www.emory.edu/WHSC/HSNEWS/releases/feb02/plaato.html -
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Published on: 2/27/2002
Last Visited: 3/1/2002
"By permanently occluding this structure, clots that develop there are unable to break off, travel to the brain and result in stroke," explains Emory Heart Center interventional cardiologist Peter Block, M.D., who is heading the PLAATO research team at Emory.
The procedure offers new hope to people at risk of stroke from atrial fibrillation.Affecting approximately 2.2 million Americans, AF results when the upper chambers of the heart contract in a rapid and/or disorganized way.Stroke, the most serious consequence of AF, can develop as a result of blood clots that form in the erratically contracting upper chamber of the heart.AF increases the risk of stroke five fold and accounts for approximately twenty percent of all strokes.
Anticoagulants are the current standard -- and only proven -- therapy for the prevention of stroke due to AF.
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"Chronic warfarin therapy is known to reduce the risk of thromboembolic events among those with AF and clinical risk factors but it is one of the most difficult medications to administer in clinical practice," says Dr. Block, who recently performed the first PLAATO procedures in Georgia and among the first in the nation.He points out that frequent blood testing is required and, in addition, warfarin is difficult to manage because of the large number of drugs and foods that interact with the anticoagulant.Patients also have up to a two percent risk a year for life threatening hemorrhages.
"The PLAATO procedure represents a promising therapeutic alternative to a failed regimen of medication and frequent blood monitoring.It has the potential to prevent thromboembolic stroke in this high-risk population with a single catheter intervention," says Dr. Block."If the trials are successful, the device could be an important interventional cardiology procedure."
Since 1975 Emory Crawford Long Carlyle Fraser Heart Center has been recognized internationally for its work in the diagnosis treatment and prevention of heart and lung disease.The Carlyle Fraser Heart Center is part of the Emory Heart Center, ranked in the top ten AmericaĆs Best Hospitals by US News & World Report.Emory Hospitals include Emory University Hospital, a 587-bed hospital located on the Emory University campus in northeast Atlanta, Crawford Long Hospital, Emory's 583-bed, community-based hospital in midtown and Wesley Woods Geriatric Hospital, a100-bed hospital located on the Emory campus.Emory Hospitals are components of EMORY HEALTHCARE, the most comprehensive health care system in Atlanta.