Dr. Oren Beske

Oren Beske, Ph.D., Director, In Vitro Services
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Oren Beske, Ph.D.

Director, In Vitro Services

Dr. Beske has greater than 15 years of cell biology research experience.He has a Ph.D. in cell biology from the University of California, San Francisco.Following a stint as a professor at San Francisco State University he joined Vitra Bioscience and led a team of scientists developing novel cell based assay technologies with applications in drug discovery and basic science research.Subsequently, he founded Rilato Bioscience (recently acquired) and COREX Scientific where he continues to serve in an advisory role.Dr. Beske has multiple patents and publications pertaining to cell biology, multiplexed assays, and small molecule drug discovery.

Oren Beske, PhD, Director, Aragen Bioscience, Inc..

Dr. Oren Beske, Head of Cell Biology, Virtual Arrays Inc.Virtual Arrays CellCard technology enables the simultaneous interrogation (multiplexing) of receptors in the same microtiter well.Our initial development of this system has focused on GPCRs.Using our encoded particle technology we have been able to mulitplex the identification of both agonists and antagonists to several families of GPCRs.Our data demonstrate that this technology can significantly decrease the amount of time, cost, and compound usage required to generate target specific hits.Our goal is to develop this technology to enable the multiplex screening of hundreds of receptors simultaneously, thereby providing an unprecedented insight into hit specificity in compound libraries, otherwise missed by conventional screens.

"About three years ago, some of the big pharmas started moving toward using more cellular assays in HTS," says Oren Beske, head of cell biology at Vitra Bioscience.

With Virtual Arrays' CellCard technology, simultaneous selectivity and potency data can be obtained from the same assay well," commented Oren Beske, Virtual Arrays' Head of Cell Biology."The ability of the CellCard system to characterize multiple cell lines in the same microtiter well enables researchers to understand and profile the activity of compounds along numerous dimensions, and thereby, further characterize and optimize these compounds."Dr. Beske presented the features and benefits of the CellCard System for the Company's podium presentation at the SBS meeting where the key focus was "High Information Content Screening."

Also at SBS, Virtual Arrays had two poster presentations, each of which highlighted different applications of its CellCard platform.The first, entitled "Multiplexed Cellular Analysis Using CellCard Arrays and a High Throughput Transfection Approach," demonstrated how Virtual Arrays' technology can be combined with reverse transfection to enable rapid generation of cellular arrays for a diversity of applications.

The second poster presentation further demonstrated the broad applicability and high information content capabilities of the CellCard technology.The poster was entitled "Multiplex Identification of Potent and Selective Anticancer Drugs Using CellCard Arrays."It described experiments where proliferation assays were multiplexed demonstrating the ability of the CellCard platform to generate specificity, selectivity and potency data within a single well.

Director Cell Biology - Oren Beske, Ph.D.Dr. Beske has over 10 years of cell biology expertise in cellular imaging technology and applications.Oren joined Vitra Bioscience to develop applications of encoded carrier technology in cell-based assays and has been instrumental in the development and success of the CellCard (TM) technology.

Dr. Beske holds a PhD in Cell Biology from UCSF.
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Oren Beske, Ph.D.

Oren Beske

Head of Cell Biology, Vitra Bioscience, Inc.